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Keywords: Diazepam
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Journal Articles
Treatment with Diazepam in Acute Stroke Prevents Poststroke Seizures: A Substudy of the EGASIS Trial
Open AccessJulia H. van Tuijl, Elisabeth P.M. van Raak, Robert J. van Oostenbrugge, Albert P. Aldenkamp, Rob P.W. Rouhl
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2021) 50 (2): 216–221.
Published Online: 19 January 2021
... early administration of diazepam prevents the development of seizures in acute stroke patients. Methods: We performed a substudy of the EGASIS trial, a multicenter double-blind, randomized trial in which acute stroke patients were treated with diazepam or placebo for 3 days. Follow-up was after 2 weeks...
Journal Articles
Diazepam to Improve Acute Stroke Outcome: Results of the Early GABA-Ergic Activation Study In Stroke Trial: A Randomized Double-Blind Placebo-Controlled Trial
Available to Purchase
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2006) 21 (1-2): 120–127.
Published Online: 13 January 2006
...J. Lodder; L. van Raak; A. Hilton; E. Hardy; A. Kessels Background: We tested whether diazepam, a GABA-ergic drug that also inhibits brain nitric monoxide formation, improves acute stroke prognosis. Methods: 880 patients, randomized within 12 h of acute stroke, received diazepam 10 mg or placebo...
Journal Articles
Diazepam Treatment to Increase the Cerebral GABAergic Activity in Acute Stroke: A Feasibility Study in 104 Patients
Available to Purchase
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2000) 10 (6): 437–440.
Published Online: 27 October 2000
...J. Lodder; G.J. Luijckx; L. van Raak; F. Kessels In preparation of a trial on the neuroprotective effect of GABAergic activation by a benzodiazepine, we performed a feasibility study in 104 patients with acute (less than 24 h) stroke. 5 mg diazepam twice daily for 5 days (n = 44) was well tolerated...