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1-20 of 25
Keywords: Clinical trial
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Journal Articles
Ruixue Liu, Chen Chen, Feifeng Liu, Yapeng Lin, Hongling Chu, Hueiming Liu, Craig S. Anderson, Jie Yang, Gang Li, Lili Song, Menglu Ouyang
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis 1–7.
Published Online: 05 September 2024
..., quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Process evaluation Stroke Intensive BP lowering Emergency Clinical...
Journal Articles
Qiang Li, Craig S. Anderson, Rustam Al-Shahi Salman, Graeme J. Hankey, Laurent Billot, Yang Zhao, Guanghai Tang, Jianwen Guo, Lili Song, on behalf of the CHAIN Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis 1–6.
Published Online: 23 July 2024
..., instructions or products referred to in the content or advertisements. 2024 Intracerebral hemorrhage Stroke Clinical trial Chinese herbal medicine Statistical analysis plan The Chinese Herbal medicine in Acute INtracerebral hemorrhage (CHAIN) trial involves an investigation of a promising...
Journal Articles
Laurent Billot, Chen Chen, Lili Song, Yapeng Lin, Feifeng Liu, Xiaoying Chen, Hisatomi Arima, Philip M. Bath, Gary A. Ford, Thompson G. Robinson, Else Charlotte Sandset, Jeffrey L. Saver, Nikola Sprigg, H. Bart van der Worp, Jie Yang, Gang Li, Craig S. Anderson, on behalf of the INTERACT4 Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis 1–4.
Published Online: 30 May 2024
..., instructions or products referred to in the content or advertisements. 2024 Acute stroke Clinical trial Ambulance Hypertension Statistical analysis plan Timely treatment of acute stroke is important for both intracerebral hemorrhage (ICH) and acute ischemic stroke (AIS) [ 1‒3 ]. Continuous...
Journal Articles
Weili Li, Ming Wei, Lan Liu, Jing Lan, Chuanjie Wu, Wenbo Zhao, Chuanhui Li, Jian Chen, Chengbei Hou, Qingfeng Ma, Xunming Ji, OPENS-2 Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis 1–8.
Published Online: 03 July 2023
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Acute ischemic stroke Normobaric hyperoxia Endovascular treatment Clinical trial Protocol Intravenous thrombolysis (IVT) and endovascular treatment (EVT...
Journal Articles
Subject Area:
Cardiovascular System
,
Karger e-Journal Backfile Collection 2023
,
Neurology and Neuroscience
Laurent Billot, Lili Song, Xin Hu, Lu Ma, Menglu Ouyang, Xiaoying Chen, Chao You, Craig S. Anderson, on behalf of the INTERACT3 Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (3): 251–254.
Published Online: 23 May 2023
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2022 Intracerebral hemorrhage Stroke Clinical trial Hypertension Cluster Statistical analysis plan This study is jointly funded by the Department for International...
Journal Articles
Subject Area:
Cardiovascular System
,
Karger e-Journal Backfile Collection 2023
,
Neurology and Neuroscience
Christopher Li Hsian Chen, Yogesh Pokharkar, Narayanaswamy Venketasubramanian, for the CHIMES and CHIMES-E Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (2): 160–165.
Published Online: 02 May 2023
..., is associated with functional recovery assessed by the modified Rankin Score (mRS). A secondary objective was to apply this new tool in the context of a clinical trial. Methods: The analysed population considered for this research included subjects from a large published, double-blind, multicentre trial...
Journal Articles
Subject Area:
Cardiovascular System
,
Karger e-Journal Backfile Collection 2023
,
Neurology and Neuroscience
Lei Si, Xiaoying Chen, Menglu Ouyang, Xia Wang, Guofang Chen, Yong-jun Cao, Guojun Wu, Jinli Zhang, Jingfen Zhang, YuKai Liu, Shihong Zhang, Lili Song, Candice Delcourt, Hisatomi Arima, Lidan Wang, Thomas Lung, Mingsheng Chen, Craig S. Anderson, Stephen Jan, for the ENCHANTED Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (2): 145–152.
Published Online: 02 May 2023
... stroke Clinical trial Health economics Alteplase Cost-effectiveness In the second scenario analysis, the equivalence margin for costs was set as an average inpatient cost of stroke in China, where the average hospitalization cost for a case of AIS was 17,731 Chinese Yuan (USD 5,153) [ 24...
Journal Articles
Subject Area:
Cardiovascular System
,
Karger e-Journal Backfile Collection 2023
,
Neurology and Neuroscience
Lan Gao, Marj Moodie, Christopher Levi, Longting Lin, Xin Cheng, Timothy Kleinig, Ken Butcher, Bernard Yan, Andrew Bivard, Mark Parsons
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2023) 52 (2): 137–144.
Published Online: 14 December 2022
...Lan Gao; Marj Moodie; Christopher Levi; Longting Lin; Xin Cheng; Timothy Kleinig; Ken Butcher; Bernard Yan; Andrew Bivard; Mark Parsons Introduction: We aimed to assess the long-term health outcomes and costs of endovascular thrombectomy (EVT) using clinical trials and real-world evidence...
Journal Articles
Menglu Ouyang, Craig S. Anderson, Lili Song, Stephen Jan, Lingli Sun, Guojuan Cheng, Honglin Chu, Xin Hu, Lu Ma, Xiaoying Chen, Chao You, Hueiming Liu
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2022) 51 (3): 373–383.
Published Online: 20 December 2021
... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2021 Process evaluation Clinical trial Care bundle Management...
Journal Articles
Chen Chen, Xia Wang, Xiaoying Chen, Menglu Ouyang, Lingli Sun, Hisatomi Arima, Thompson Robinson, Richard I. Lindley, John Chalmers, Gang Li, Lili Song, Craig S. Anderson, for the ENCHANTED Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2021) 50 (5): 560–566.
Published Online: 21 June 2021
... (OR 1.51, 95% CI 1.23–1.86; p = 0.0001) and neurological deterioration within 24 h (OR 1.58, 95% CI 1.18–2.12; p = 0.002). Conclusions: Within the context of an international clinical trial of thrombolyzed AIS patients, demography, risk factors, management, and odds of early neurological deterioration...
Journal Articles
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2020) 49 (3): 244–252.
Published Online: 25 June 2020
... Hemorrhage 2 trial. Design: Randomized, multicenter, 2 group, open-label clinical trial. Setting: A total of 110 sites in the USA, Japan, China, Taiwan, South Korea, and Germany. Patients: A total of 1,000 patients underwent randomization from May 2011 till September 2015. Interventions: We analyzed...
Journal Articles
Narayanaswamy Venketasubramanian, Rajesh B. Moorakonda, Qingshu Lu, Christopher L.H. Chen, On behalf of the CHIMES Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2020) 49 (2): 192–199.
Published Online: 03 March 2020
...Narayanaswamy Venketasubramanian; Rajesh B. Moorakonda; Qingshu Lu; Christopher L.H. Chen; On behalf of the CHIMES Investigators Background: Most comparative clinical trials are designed to assess the treatment effect for efficacy endpoints, with less emphasis on the analysis of safety outcomes...
Journal Articles
Nijasri C. Suwanwela, Christopher L.H. Chen, Chun Fan Lee, Sherry H. Young, San San Tay, Thirugnanam Umapathi, Annabelle Y. Lao, Herminigildo H. Gan, Alejandro C. Baroque II, Jose C. Navarro, Hui Meng Chang, Joel M. Advincula, Sombat Muengtaweepongsa, Bernard P.L. Chan, Carlos L. Chua, Nirmala Wijekoon, H. Asita de Silva, John Harold B. Hiyadan, Ka Sing Lawrence Wong, Niphon Poungvarin, Gaik Bee Eow, Narayanaswamy Venketasubramanian, CHIMES-E Study Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2018) 46 (1-2): 82–88.
Published Online: 05 September 2018
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Acute stroke Stroke recovery MLC601 NeuroAiD Rehabilitation Combination Clinical trial Long-term outcome Stroke recovery is complex and is likely to occur...
Journal Articles
Narayanaswamy Venketasubramanian, Chun Fan Lee, Sherry H. Young, San San Tay, Thirugnanam Umapathi, Annabelle Y. Lao, Herminigildo H. Gan, Alejandro C. Baroque II, Jose C. Navarro, Hui Meng Chang, Joel M. Advincula, Sombat Muengtaweepongsa, Bernard P.L. Chan, Carlos L. Chua, Nirmala Wijekoon, H. Asita de Silva, John Harold B. Hiyadan, Nijasri C. Suwanwela, K.S. Lawrence Wong, Niphon Poungvarin, Gaik Bee Eow, Christopher L.H. Chen, for the CHIMES-E Study Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2017) 43 (1-2): 36–42.
Published Online: 15 November 2016
... results in experimental studies [ 3 ], but have failed in many clinical trials due to a variety of factors including patient selection and length of follow-up. Acute stroke Stroke recovery MLC601 NeuroAiD Prognosis Clinical trial Long-term outcome 5 08 2016 4 10 2016 15 11...
Journal Articles
Narayanaswamy Venketasubramanian, Sherry H. Young, San San Tay, Thirugnanam Umapathi, Annabelle Y. Lao, Herminigildo H. Gan, Alejandro C. Baroque II, Jose C. Navarro, Hui Meng Chang, Joel M. Advincula, Sombat Muengtaweepongsa, Bernard P.L. Chan, Carlos L. Chua, Nirmala Wijekoon, H. Asita de Silva, John Harold B. Hiyadan, Nijasri C. Suwanwela, K.S. Lawrence Wong, Niphon Poungvarin, Gaik Bee Eow, Chun Fan Lee, Christopher L.H. Chen, for the CHIMES-E Study Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2015) 39 (5-6): 309–318.
Published Online: 22 April 2015
... or advertisements. Acute stroke Traditional Chinese medicine Stroke recovery MLC601 NeuroAiD Clinical trial Long-term outcome Stroke is a major cause of death and disability with only a limited number of treatment options to improve functional outcome after stroke, including thrombolytic therapy...
Journal Articles
Xia Wang, Hisatomi Arima, Rustam Al-Shahi Salman, Mark Woodward, Emma Heeley, Christian Stapf, Pablo M. Lavados, Thompson Robinson, Yining Huang, Jiguang Wang, Candice Delcourt, Craig S. Anderson, for the INTERACT Investigators
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2015) 39 (3-4): 242–248.
Published Online: 25 March 2015
... follow-up at 7, 28, and 90 days, post-randomization. Clinical trial registration information: http://www.clinicaltrials.gov , NCT00226096 and NCT00716079. Results: Intensive BP lowering resulted in a significant favorable distribution of mRS scores for better functioning (odds ratio 1.13, 95% confidence...
Journal Articles
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2001) 11 (Suppl. 1): 100–104.
Published Online: 01 April 2010
... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Anticoagulants Aspirin Secondary prevention Clinical trial Oral anticoagulation...
Journal Articles
Nerses Sanossian, Sidney Starkman, David S. Liebeskind, Latisha K. Ali, Lucas Restrepo, Scott Hamilton, Robin Conwit, Jeffrey L. Saver
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2009) 28 (6): 539–544.
Published Online: 16 October 2009
.... National Institutes of Health (NIH) 10.13039/100000002 Prehospital trials Stroke Magnesium Informed consent Clinical trial Original Paper Cerebrovasc Dis 2009;28:539 544 DOI: 10.1159/000247596 Received: February 9, 2009 Accepted: June 3, 2009 Published online: October 16, 2009 Simultaneous...
Journal Articles
Keng He Kong, Seng Kwee Wee, Chwee Yin Ng, Karen Chua, Kay Fei Chan, N. Venketasubramanian, Christopher Chen
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2009) 28 (5): 514–521.
Published Online: 09 October 2009
... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Stroke Neuroaid Motor rehabilitation Functional recovery Clinical trial Original Paper Cerebrovasc Dis 2009;28:514 521 DOI: 10.1159/000247001 Received: May 13, 2009...
Journal Articles
Geneviève Demarquay, Laurent Derex, Norbert Nighoghossian, Patrice Adeleine, Frédéric Philippeau, Jérôme Honnorat, Paul Trouillas
Journal:
Cerebrovascular Diseases
Cerebrovasc Dis (2005) 19 (2): 65–68.
Published Online: 03 February 2005
... the modalities of informed consent in urgent therapeutic stroke trials, the awareness of patients and relatives regarding stroke clinical trials and the impact of decision making on patients and relatives. Methods: We present a study of 56 acute ischemic stroke patients who were randomized in 4 trials (2 trials...
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