...: In patients with acute ischemic stroke (AIS) secondary to intracranial large vessel occlusion, optimal blood pressure (BP) management following endovascular treatment (EVT) has not yet been established. The randomized trial on Hemodynamic Optimization of Cerebral Perfusion after Successful Endovascular...

... is a major safety concern of intensive systolic blood pressure (SBP) lowering. We aimed to determine the effect of this treatment on early change in renal function in participants of the international Enhanced Control of Hypertension and Thrombolysis Stroke Study (ENCHANTED). Methods: Post hoc analysis...

... min), of whom 101 patients (35%) had lobar haematoma. Mode of referral was stroke code in 129 patients (38%), transfer from other hospital in 143 patients (43%), and arrival by other means in 60 patients (18%). Overall, 143 of 216 (66%) patients with systolic blood pressure >150 mm Hg received IV...

... was determined from either “high blood pressure,” “HTN,” or “hypertension” listed in the free text for relevant past medical history. Pre-existing TIA and/or stroke was determined from either “TIA,” “Transient ischaemic attack,” or “stroke” listed in the free text for relevant past medical history. Pre-existing...

...Sritheja Reddy; Naveen Kumar Paramasivan; Sapna Erat Sreedharan; Sajith Sukumaran; Jissa Vinoda Thulaseedharan; Padmavathy N. Sylaja Introduction: Elevated admission blood pressure (BP) and BP variability have been shown to be associated with poor outcomes in most studies, while few studies have...

...Jun Young Chang; Sang Beom Jeon; Jung Hwa Lee; O-Ki Kwon; Moon-Ku Han Background: Blood pressure variability (BPV) is associated with target organ damage progression and increased cardiovascular events, including stroke. The aim of this study was to evaluate the associations between short-term BPV...

...Simona Lattanzi; Claudia Cagnetti; Leandro Provinciali; Mauro Silvestrini Background: The optimal treatment of high blood pressure (BP) after acute intra-cerebral hemorrhage (ICH) is controversial. Summary: The aim of the study was to evaluate the safety and efficacy of early intensive vs...

...-point score based on 9 items (Intracranial-B 2 LEED 3 S score - low body mass index, blood pressure, lacune, elderly, Asian ethnicity, coronary artery or cerebrovascular disease history, dual antithrombotic agent or oral anticoagulant, gender) was derived from the PERFORM trial. In PERFORM, the observed...

... identified hematoma volume as the key independent predictor of PDR. The volume of perihematomal edema, lobar hematoma location and low diastolic blood pressure at admission were further predictors. Although the occurrence of PDR correlated with in-hospital mortality (75.0 vs. 43.4%, p < 0.001...

...Shuping Liu; Chengyan Li; Tao Li; Jing Xiong; Xueqing Zhao Background: Accumulating evidence suggests that high blood pressure (BP) increases the risk of cerebral oedema and haemorrhagic transformation of the ischaemic stroke (IS), and that low BP in acute ischaemic stroke (AIS) is associated...

... of an association between off-hour (weekend, holiday, or night-time) hospital admission and adverse outcome in intracerebral hemorrhage (ICH). We determined the association between off-hour admissions and poor clinical outcome, and of any differential effect of early intensive blood pressure (BP) lowering treatment...

...Andreas Charidimou; Enikö Kovari aging alzheimer's disease amyloid angiopathy biomarkers bleeding blood pressure brain hemorrhage Brain Imaging cerebral amyloid angiopathy cerebral microangiopathies References 1. Greenberg SM: Small vessels, big problems. N Engl J Med...

... the benefit of cilostazol is sustained in patients with a high risk of bleeding has not been examined. Methods: We conducted a subanalysis of CSPS 2 to examine whether known risk factors for hemorrhagic stroke, such as stroke subtype and systolic blood pressure (SBP), influence the efficacy of the study drugs...

...Christopher Elnan Kvistad; Nicola Logallo; Halvor Oygarden; Lars Thomassen; Ulrike Waje-Andreassen; Halvor Naess Background: Transient elevated blood pressure (BP) is frequent in patients presenting with acute ischemic stroke. The pathophysiology of this response is not clear and its effect...

... proportional hazards regression model that included age, body mass index, cohort and either serum total cholesterol or systolic blood pressure as covariates. Fractions of deaths attributable to the coexistence of these risk factors were also calculated. Results: The multivariate-adjusted hazard ratios in male...

... hemorrhage (SAH) was 27.3, 55.9 and 16.8%, respectively. Mean age and systolic and diastolic blood pressures (BPs) were significantly higher in stroke cases. CH and CI occurred more frequently in men, whereas SAH occurred more frequently in women. Serum total cholesterol (TC) <160 mg/dl was a risk factor...

... repeatedly been reported in stroke patients. We hypothesize that blood pressure (BP) derangements in the acute phase relate to the impairment of baroreflex. Methods: We assessed baroreflex sensitivity (BRS) in 109 acute stroke patients with both ischemic and hemorrhagic stroke using the sequential cross...

...Fiona J. Bath; Philip M.W. Bath Hypertension is associated with a poor outcome in acute stroke. Paradoxically, lowering blood pressure (BP) may also worsen outcome, probably by reducing regional cerebral blood flow and worsening ischaemia. However, no large randomised controlled trials (RCTs) have...

...Gillian M. Sare; Chamila Geeganage; Philip M.W. Bath High blood pressure (BP) is present in 80% of patients with acute ischaemic stroke and is independently associated with poor outcome. Although this epidemiology suggests that BP should be lowered acutely, concerns about dysfunctional cerebral...

... by an oscillometric method. Results: The baPWV was most affected by the instantaneous systolic blood pressure, and was significantly higher in stroke patients than control subjects (1,721 ± 395 cm/s vs. 1,657 ± 366 cm/s, p = 0.03). However, the baPWV did not differ significantly with a specific type of stroke...