... among stroke patients. This study aimed to assess how pre-stroke frailty, an aging-related syndrome characterized by a loss in the physiologic reserve of numerous body functions, affected the degree of leptomeningeal collateral flow in the setting of acute ischemic stroke. Methods: A consecutive series...

...Bingyang Zhao; Congping Wang; Wenzhao Liang; Zhongyu Zhao; Jing Mang Introduction: Selecting thrombectomy techniques for acute ischemic stroke due to large vessel occlusion significantly affects outcomes and costs. This study introduces the Bifurcation-Invisible (BI) sign identified on initial...

... objective of this trial is to investigate the efficacy and safety of selective endovascular brain hypothermia with edaravone dexborneol for endovascular treatment in acute ischemic stroke (AIS). Methods: The SHE study is a multicenter, single-blind, randomized controlled clinical trial. Patients with acute...

...Ali Hammed; Almonzer Al-Qiami; Ahmad Alzawahreh; Josef Rosenbauer; Eman Ayman Nada; Zina Otmani; Nada G. Hamam; Asmaa Zakria Alnajjar; Elsayed Mohamed Hammad; Rawan Hamamreh; Karel Kostev; Gregor Richter; Christian Tanislav Introduction: The treatment of acute ischemic stroke due to large artery...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2024 Acute ischemic stroke 23Na-MRI Edema Ischemic cerebral stroke is a dynamic process with a complex...

...Jonathan Ince; Ronney B. Panerai; Angela S.M. Salinet; Man Y. Lam; Osian Llwyd; Victoria J. Haunton; Thompson G. Robinson; Jatinder S. Minhas Introduction: Cerebral autoregulation (CA) is impaired in acute ischemic stroke (AIS) and is associated with worse patient outcomes, but the underlying...

...Alejandro M. Brunser; Pablo M. Lavados; Paula Muñoz-Venturelli; Verónica V. Olavarría; Eloy Mansilla; Gabriel Cavada; Pablo Enrique González Introduction: Scarce data exist about clinical/radiological differences between acute ischemic strokes diagnosed in the emergency room (AISER) and stroke...

... treated with mechanical thrombectomy (MT) for acute ischemic stroke (AIS) remains unresolved. We aimed to elucidate these differences by employing computed tomography perfusion (CTP) imaging before MT and examining the influence of perfusion deficits on the 90-day functional outcome. Methods: This single...

... of stroke patients at two centers who met the following criteria: (i) anterior large vessel occlusion acute ischemic stroke, (ii) attempted EVT, and (iii) had 3T MRI post-EVT at 24-h and 5-day. We defined “early” and “late” lesion growth as ≥10 mL lesion growth between baseline and 24-h diffusion-weighted...

...Kun An; Chun Chen; Meijuan Dong; Wei Chen; Yongjun Cao Introduction: Post-thrombectomy intraparenchymal hyperdensity (PTIH) in patients with acute ischemic stroke is a common CT sign, making it difficult for physicians to distinguish intracerebral hemorrhage in the early post-thrombectomy period...

...Sonia Torres-Riera; Adrià Arboix; Olga Parra; Luís García-Eroles; María-José Sánchez-López Introduction: There are limited data on the outcome of acute ischemic stroke in oldest old women. We assessed clinical risk factors for in-hospital mortality in women aged 85 years or more with acute ischemic...

... of the ENCHANTED BP-arm in which thrombolyzed patients with acute ischemic stroke (AIS) were randomized to intensive (target 130–140 mm Hg within 1 h) or guideline-recommended (target <180 mm Hg) management within 6 h of symptom onset. Primary outcome is the early change in renal function, defined...

...Wei Yu; Chao Xia; Bo Tao; Yuan Xiao; Ziyang Gao; Fei Zhu; Qiannan Zhao; Su Lui Background: The hyperdense lesion on non-contrast CT (NCCT) is a common postoperative phenomenon in acute ischemic stroke patients who are treated with endovascular therapy (EVT). Both contrast extravasation...

.... 2023 Fibrinogen-to-albumin ratio Acute ischemic stroke Adverse outcomes Poor functional outcomes Ischemic stroke is characterized by high incidence, poor prognosis, and high economic burden [ 1, 2 ]. Inflammation is a common risk factor for adverse outcomes after ischemic stroke [ 3‒6...

...Bingyang Zhao; Wenzhao Liang; Xinzhao Jiang; Zhongyu Zhao; Lei Yan; Jing Mang; Zhongxin Xu Introduction: The truncal-type occlusion (TTO) sign observed during endovascular thrombectomy is thought to predict the etiology and prognosis of acute ischemic stroke (AIS) due to large vessel occlusion (LVO...

... those receiving BMM alone. Our findings support the idea that age alone should not be used as an absolute criterion for determining eligibility for MT. The 2018 AHA/ASA guidelines for the management of acute ischemic stroke recommend the use of MT in qualifying LVO cases [ 19 ]. Several of the large...

... outcomes and all-cause mortality post-stroke. However, the association between TyG index and recurrent stroke after acute ischemic stroke (AIS) has not been well described. We aimed to identify whether the TyG index was associated with 1-year recurrent stroke after AIS. Methods: Baseline patient...

...%) but not within 0–3 h (65.84 vs. 63.95%). However, there was no interaction effect regarding all outcomes after the Bonferroni correction. Conclusions: Our results did not support thrombectomy-alone administration within 3–4.5 h in patients with acute ischemic stroke from large-vessel occlusion in the subgroup...

... rhythm dysfunction in ischemic stroke remains unknown. This study observed the characteristics of melatonin secretion in acute ischemic stroke patients and evaluated whether melatonin rhythm impacts the prognosis after stroke by assessing the neurological function, cognition, emotion, and quality of life...

... endovascular treatment (EVT) and were randomized within 6 h from symptom onset. Based on the data of the modified Rankin Scale (mRS) score at 90 days from the normobaric hyperoxia combined with EVT for acute ischemic stroke (OPENS: NCT03620370) trial, 284 patients will be included to achieve a 90% power...