Abstract
We present the clinical, radiological and autopsy findings in a 32-year-old woman with primary oxalosis, who suffered recurrent bilateral carotid territory infarcts. The overall features were those of moya-moya syndrome, with bilateral, ultimately thrombotic, occlusion of the distal internal carotid arteries. Vessel pathology suggests an underlying intimal vasculopathy, the possible relation of which to the patient’s metabolic abnormality is discussed.
References
1.
Chaplin AJ: Histopathological occurrence and characterisation of calcium oxalate: A review. J Clin Pathol 1977;30:800–811.
2.
Massie BM, Bharati S, Scheinman MM, Lev M, Desai J, Rubeson E, Schmidt W: Primary oxalosis with pan condution cardiac disease – Electrophysiologic and anatomic correlation. Circulation 1981;64:845–852.
3.
Coltart DJ, Hudson REB: Primary oxalosis of the heart: A cause of heart block. Br Heart J 1971;33:315–319.
4.
Blackburn WE, McRoberts JW, Bhathena D, Vazquez M, Luke RG: Severe vascular complications in oxalosis after bilateral nephrectomy. Ann Intern Med 1975;82:44–46.
5.
Arbus GS, Sniderman S: Oxalosis with peripheral gangrene. Arch Pathol 1974;97:107–110.
6.
Mohr W, Hey D: Oxalose mit Manifestation in Erwachsenenalter. Virchows Arch Pathol Anat 1969;347:185–196.
7.
Di Pasquale G, Ribani M, Andreoli A, Zampa GA, Pinelli G: Cardioembolic stroke in primary oxalosis with cardiac involvement. Stroke 1989;20:1403–1406.
8.
Takeuchi K: Occlusive disease of the carotid artery. Rec Adv Res Nerv Syst (Tokyo) 1961;5:511–543.
9.
Suzuki J, Kodama N: Moya-moya disease – A review. Stroke 1983;14:104–109.
10.
Suzuki J, Takaku A: Cerebrovascular ‘moya-moya’ disease – Disease showing abnormal net-like vessels in base of brain. Arch Neurol 1969;20:288–299.
11.
Nishimoto A, Takeuchi S: Abnormal cerebral vascular network related to the internal carotid arteries. J Neurosurg 1968;29:255–260.
12.
Olsen S: The brain in uremia. Acta Psychiatr Scand 1961;36(suppl 156):1–128.
13.
Sommer BG, Henry ML, Ferguson RM: Cyclosporine-associated arteriopathy. Transplant Proc 1986;18(suppl 1):151–157.
14.
Zoja C, Furci L, Ghilardi F, Zilio P, Benigni A, Remuzzi G: Cyclosporin-induced endothelial cell injury. Lab Invest 1986;55:455–462.
15.
Fogo A, Hakim RC, Sugiura M, Inagami T, Kon V: Severe endothelial injury in a renal transplant patient receiving cyclosporine. Transplantation 1990;49:1190–1192.
16.
Hinchey J, Chaves C, Appignani B, Breen J, Pao L, Wang A, Pessin M, Lamy C, Mas J, Caplan LR: A reversible posterior leukoencephalopathy syndrome. N Engl J Med 1996;334:494–500.
17.
Gotoh F: Annual Report of the Research Committee on Spontaneous Occlusion of the Circle of Willis (Moya-Moya Disease), Japan, Tokyo, Ministry of Health and Welfare, 1982.
18.
Yonekawa Y, Goto Y, Ogata N: Moya-moya disease: Diagnosis, treatment and recent achievement; in Barnett HJM, Mohr JP, Stein BM, Yatsu FM (eds): Stroke, Pathophysiology, Diagnosis and Management, ed 2. New York, Churchill Livingstone, 1992, vol 26, pp 721–747.
19.
Yamashita M, Tanaka K, Kishikawa T, Yokota K: Moya-moya disease associated with renovascular hypertension. Hum Pathol 1984;15:191–193.
20.
Yamashita M, Oka K, Tanaka K: Cervico-cephalic arterial thrombi and thromboemboli in moya-moya disease – possible correlation with progressive intimal thickening in the intracranial arteries. Stroke 1984;15:264–270.
21.
Hosoda Y: Pathology of so-called ‘spontaneous occlusion of the circle of Willis’. Pathol Annu 1984;part 2:221–244.
22.
Kaneko H, Okamura A, Nishida K, Watanabe M: An autopsy case of intracranial rete mirabile. Brain Nerve (Tokyo) 1971;23:1381–1387.
23.
Headache Classification Committee of the International Headache Society: Classification and diagnostic criteria for headache disorders, cranial neuralgias and facial pain. Cephalgia 1988;8:13–28.
24.
Welch KMA, Levine SR: Migraine-related stroke in the context of the International Headache Society Classification of Head Pain. Arch Neurol 1990;47:458–462.
25.
Hughes JT, Schianchi PM: Cerebral artery spasm: A histologic study at necropsy of the blood vessels in cases of subarachnoid haemorrhage. J Neurosurg 1978;48:515–525.
26.
Conway LW, McDonald LW: Structural changes in the intradural arteries following subarachnoid haemorrhage. J Neurosurg 1972;37:715–723.
27.
Jonis I, Majno G: Endothelial changes induced by arterial spasm. Am J Pathol 1981;102:346–358.
28.
Clower BR, Smith RR, Haining JL, Lockard J: Constrictive endarteropathy following experimental subarachnoid haemorrhage. Stroke 1981;12:501–508.
29.
Solomon S, Lipton RB, Harris PY: Arterial stenosis in migraine: Spasm or arteriopathy? Headache 1990;30:52–61.
1998
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.
