Background: Mania is a rare consequence of stroke and according to the sparse published information it is difficult to describe its demographic, clinical and prognostic characteristics. Methods: We performed a systematic review of all cases of mania and stroke to describe those characteristics. Studies were identified from comprehensive searches of electronic databases, reference lists of the studies collected and handbooks. Two authors independently assessed abstracts, and collected and extracted data. Results: From 265 abstracts, 139 were potentially relevant. For the first analysis, which tries to answer the clinical question of the relationship between mania and stroke, 49 studies met the inclusion criteria and described 74 cases. For the second analysis, we looked for an explicit temporal and causal relationship between manic symptoms and stroke, and selected 32 studies describing 49 cases. In both analyses, the typical patient was male, without a personal or family history of psychiatric disorder, with at least one vascular risk factor, but without subcortical atrophy and had suffered a right cerebral infarct. The majority of patients (92%) presented elevated mood as the first symptom. The other frequent symptoms were an increased rate or amount of speech (71%), insomnia (69%) and agitation (63%). Conclusions: Post-stroke mania should be considered in any manic patient who presents concomitant neurological focal deficits and is older than expected for the onset of primary mania. The results of a systematic study of mania in acute stroke with subsequent follow-up and data from diffusion MR or perfusion CT in a multicenter study with a central database would be relevant.

1.
American Psychiatric Association: Mood disorders; in: Diagnostic and Statistical Manual of Mental Disorders, ed 4, text revision. Washington, American Psychiatric Association, 2002, pp 345–428.
2.
Ferro JM, Caeiro L, Santos C: Poststroke emotional and behavior impairment: a narrative review. Cerebrovasc Dis 2009;27(suppl 1):197–203.
3.
Sadock BJ, Sadock VA: Mood disorders; in Sadock BJ, Sadock VA (eds): Kaplan and Sadock’s Synopsis of Psychiatry. Behavioural Sciences/Clinical Psychiatry, ed 9. Philadelphia, Lippincott Williams & Wilkins, 2003, pp 534–572.
4.
Starkstein SE, Manes F: Mania and manic-like disorders; in Bogousslavsky J, Cummings JL (eds): Behaviour and Mood Disorders in Focal Brain Lesions. Cambridge, Cambridge University Press, 2000, pp 65–94.
5.
Vuilleumier P, Ghika-Schmid F, Bogousslavsky J, Assal G, Regli F: Persistent recurrence of hypomania and prosoaffective agnosia in a patient with right thalamic infarct. Neuropsychiatry Neuropsychol Behav Neurol 1998;11:40–44.
6.
Krauthammer C, Klerman G: Secondary mania. Manic syndromes associated with antecedent physical illness or drugs. Arch Gen Psychiatry 1978;35:1333–1339.
7.
Fenn D, George K: Post-stroke mania late in life involving the left hemisphere. Aust NZ J Psychiatry 1999;33:598–600.
8.
Kumar S, Jacobson RR, Sathananthan K: Seasonal cyclothymia to seasonal bipolar affective disorder: a double switch after stroke. J Neurol Neurosurg Psychiatry 1997;63:796–797.
9.
Starkstein SE, Robinson RG: Affective disorders and cerebral vascular disease. Br J Psychiatry 1989;154:170–182.
10.
Robinson RG, Boston JD, Starkstein SE, Price TR: Comparison of mania and depression after brain injury: causal factors. Am J Psychiatry 1988;145:172–178.
11.
Robinson RG: Mood disorders secondary to stroke. Semin Clin Neuropsychiatry 1997;2:244–251.
12.
Starkstein SE, Fedoroff P, Berthier ML, Robinson RG: Manic-depressive and pure manic states after brain lesions. Biol Psychiatry 1991;29:149–158.
13.
Robinson RG, Starkstein SE: Mood disorders following stroke: new findings and future directions. J Geriatr Psychiatry 1989;22:1–15.
14.
Starkstein SE, Boston JD, Robinson RG: Mechanisms of mania after brain injury. 12 case reports and review of the literature. J Nerv Ment Dis 1988;176:87–100.
15.
Starkstein SE, Pearlson GD, Boston JD, Robinson RG: Mania after brain injury. A controlled study of causative factors. Arch Neurol 1987;44:1069–1073.
16.
Cummings JL, Mendez MF: Secondary mania with focal cerebrovascular lesions. Am J Psychiatry 1984;141:1084–1087.
17.
Liu CY, Wang SJ, Fuh JL, Yang YY, Liu HC: Bipolar disorder following a stroke involving the left hemisphere. Aust NZ J Psychiatry 1996;30:688–691.
18.
Jampala VC, Abrams R: Mania secondary to left and right hemisphere damage. Am J Psychiatry 1983;140:1197–1199.
19.
Semiz M, Kavakçı O, Yontar G, Yıldırım O: Case of organic mania associated with stroke and open heart surgery. Psychiatry Clin Neurosci 2010;64:587.
20.
Duggal HS, Singh I: New-onset vascular mania in a patient with chronic depression. Neuropsychiatry Clin Neurosci 2009;21:480–482.
21.
López JD, Araúxo A, Páramo M: Late-onset bipolar disorder following right thalamic injury. Actas Esp Psiquiatr 2009;37:233–235.
22.
Havle N, Ilnem MC, Yener F, Dayan C: Secondary mania after brain stem infarct Anadolu Psikiyatri Dergisi 2009;10:163–164.
23.
Rocha FF, Carneiro JG, Pereira Pde A, Correa H, Teixeira AL: Poststroke manic symptoms: an unusual neuropsychiatric condition. Rev Bras Psiquiatr 2008;30:173–174.
24.
Dervaux A, Levasseur M: Risperidone and valproate for mania following stroke. J Neuropsychiatry Clin Neurosci 2008;20:247.
25.
da Rocha FF, Correa H, Teixeira AL: A successful outcome with valproic acid in a case of mania secondary to stroke of the right frontal lobe. Prog Neuropsychopharmacol Biol Psychiatry 2008;32:587–588.
26.
Nagaratnam N, Wong KK, Patel I: Secondary mania of vascular origin in elderly patients: a report of two clinical cases. Arch Gerontol Geriatr 2006;43:223–232.
27.
Goyal R, Sameer M, Chandrasekaran R: Mania secondary to right-sided stroke-responsive to olanzapine. Gen Hosp Psychiatry 2006;28:262–263.
28.
Mimura M, Nakagome K, Hirashima N, et al: Left frontotemporal hyperperfusion in a patient with post-stroke mania. Psychiatry Res 2005;139:263–267.
29.
Celik Y, Erdogan E, Tuglu C, Utku U: Post-stroke mania in late life due to right temporoparietal infarction. Psychiatry Clin Neurosci 2004;58:446–447.
30.
Huffman J, Stern TA: Acute psychiatric manifestations of stroke: a clinical case conference. Psychosomatics 2003;44:65–75.
31.
Gafoor R, O’Keane V: Three case reports of secondary mania: evidence supporting a right frontotemporal locus. Eur Psychiatry 2003;18:32–33.
32.
Colenda CC: Mania in late life. The challenges of treating older adults. Geriatrics 2002;57:50, 53–54.
33.
Benke T, Kurzthaler I, Schmidauer C, Moncayo R, Donnemiller E: Mania caused by a diencephalic lesion. Neuropsychologia 2002;40:245–252.
34.
Inzelberg R, Nisipeanu P, Joel D, Sarkantyus M, Carasso RL: Acute mania and hemichorea. Clin Neuropharmacol 2001;24:300–303.
35.
Franco K, Chughtai H: Steroid-induced mania in poststroke patient involving the right basal ganglion and right frontal region. Psychosomatics 2000;41:446–447.
36.
Leibson E: Anosognosia and mania associated with right thalamic haemorrhage. J Neurol Neurosurg Psychiatry 2000;68:107–108.
37.
De León OA, Furmaga KM, Kaltsounis J: Mirtazapine-induced mania in a case of post-stroke depression. J Neuropsychiatry Clin Neurosci 1999;11:115–116.
38.
Börnke C, Postert T, Przuntek H, Büttner T: Acute mania due to a right hemisphere infarction. Eur J Neurol 1998;5:407–409.
39.
Kulisevsky J, Berthier ML: A new case of fluoxetine-induced mania in post-stroke depression. Clin Neuropharmacol 1997;20:180–181.
40.
Trillet M, Vighetto A, Croisile B, Charles N, Aimard G: Hemiballismus with logorrhea and thymo-affective disinhibition caused by hematoma of the left subthalamic nucleus. Rev Neurol (Paris) 1995;151:416–419.
41.
Kulisevsky J, Avila A, Berthier ML: Bipolar affective disorder and unilateral parkinsonism after a brainstem infarction. Mov Disord 1995;10:799–802.
42.
Tohen M, Shulman KI, Satlin A: First-episode mania in late life. Am J Psychiatry 1994;151:130–132.
43.
Kumar KR, Kuruvilla K: Secondary mania following stroke. Indian J Psychiatry 1994;36:33.
44.
Berthier ML, Kulisevsky J: Fluoxetine-induced mania in a patient with post-stroke depression. Br J Psychiatry 1993;163:698–699.
45.
Turecki G, Mari Jde J, Del Porto JA: Bipolar disorder following a left basal-ganglia stroke. Br J Psychiatry 1993;163:690.
46.
Kulisevsky J, Berthier ML, Pujol J: Hemiballismus and secondary mania following a right thalamic infarction. Neurology 1993;43:1422–1424.
47.
Berthier ML: Post-stroke rapid cycling bipolar affective disorder. Br J Psychiatry 1992;160:283.
48.
Blackwell MJ: Rapid-cycling manic-depressive illness following subarachnoid haemorrhage. Br J Psychiatry 1991;159:279–280.
49.
Fawcett RG: Cerebral infarct presenting as mania. J Clin Psychiatry 1991;52:352–353.
50.
Snowdon J: A retrospective case-note study of bipolar disorder in old age. Br J Psychiatry 1991;158:485–490.
51.
Drake ME, Pakalnis A, Phillips B: Secondary mania after ventral pontine infarction. J Neuropsychiatry Clin Neurosci 1990;2:322–325.
52.
Starkstein SE, Mayberg HS, Berthier ML, Fedoroff P, Price TR, Dannals RF, Wagner HN, Leiguarda R, Robinson RG: Mania after brain injury: neuroradiological and metabolic findings. Ann Neurol 1990;27:652–659.
53.
Danel T, Comayras S, Goudemand M, et al: Troubles de l’ humeur et infarcts de l’hémisphère droit. Encephale 1989;15:549–553.
54.
Mendez MF, Adams NL, Lewandowski KS: Neurobehavioral changes associated with caudate lesions. Neurology 1989;39:349–354.
55.
Stone K: Mania in the elderly. Br J Psychiatry 1989;155:220–224.
56.
Goldschmidt TJ, Burch EA, Gutnisky G: Secondary mania from cerebral embolization with nonfocal neurologic findings. South Med J 1988;81:1309–1311.
57.
Bogousslavsky J, Ferrazzini M, Regli F, Assal G, Tanabe H, Delaloye-Bischof A: Manic delirium and frontal-like syndrome with paramedian infarction of the right thalamus. J Neurol Neurosurg Psychiatry 1988;51:116–119.
58.
Cohen MR, Niska RW: Localized right cerebral hemisphere dysfunction and recurrent mania. Am J Psychiatry 1980;137:847–848.
59.
Shulman K, Post F: Bipolar affective disorder in old age. Br J Psychiatry 1980;136:26–32.
60.
Rosenbaum AH, Barry MJ Jr: Positive therapeutic response to lithium in hypomania secondary to organic brain syndrome. Am J Psychiatry 1975;132:1072–1073.
61.
Caeiro L, Ferro JM, Albuquerque R, Figueira ML: Mania no AVC agudo. Sinapse 2002;2:90.
62.
de Toledo Ferraz Alves TC, Ferreira LK, Busatto GF: Vascular diseases and old age mental disorders: an update of neuroimaging findings. Curr Opin Psychiatry 2010;23:491–497.
63.
Marijnissen RM, Bakker M, Stek ML: First manic episode in the elderly – Consider a subdural haematoma due to head trauma as cause. Ned Tijdschr Geneeskd 2010;154:A1235.
64.
Vasudev A, Thomas A: ‘Bipolar disorder’ in the elderly: what’s in a name? Maturitas 2010;66:231–235.
65.
Amaladoss A, Le Claire JK: Late onset mania in the elderly. Int J Geriatr Psychiatry 2010;25:870–872.
66.
Bobo WV, Murphy MJ, Heckers SH: Recurring episodes of Bell’s mania after cerebrovascular accident. Psychosomatics 2009;50:285–288.
67.
Etches SM, Schmidt M, Alda M, Hajek T, Kahn DA: Resolution of bipolar II and panic disorders following subarachnoid hemorrhage. J Psychiatr Pract 2009;15:145–149.
68.
Newcomer JW: Comparing the safety and efficacy of atypical antipsychotics in psychiatric patients with comorbid medical illnesses. J Clin Psychiatry 2009;70:30–36.
69.
Braun CM, Daigneault R, Gaudelet S, Guimond A: Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition symptoms of mania: which one(s) result(s) more often from right than left hemisphere lesions? Compr Psychiatry 2008;49:441–459.
70.
Newcomer JW: Introduction: cardiovascular disease and metabolic risk factors in patients with mental illness. CNS Spectr 2008;13(6 Suppl 10):1–14.
71.
Baldwin RC: Recent understandings in geriatric affective disorder. Curr Opin Psychiatry 2007;20:539–543.
72.
Zanetti MV, Cordeiro Q, Busatto GF: Late onset bipolar disorder associated with white matter hyperintensities: a pathophysiological hypothesis. Progr Neuropsychopharmacol Biol Psychiatry 2007;31:551–556.
73.
Woo BK, Sevilla CCJ: New-onset paranoia and bipolar disorder associated with intracranial aneurysm. Neuropsychiatry Clin Neurosci 2007;19:489–490.
74.
Gruber J, Lemoine JN, Knight RT, Harvey AG: Positive mood and sleep disturbance in acquired mania following temporal lobe damage. Brain Injury 2007;21:1209–1215.
75.
Subramaniam H, Dennis MS, Byrne EJ: The role of vascular risk factors in late onset bipolar disorder. Int J Geriatr Psychiatry 2007;22:733–737.
76.
Lin HC, Tsai SY, Lee HC: Increased risk of developing stroke among patients with bipolar disorder after an acute mood episode: a six-year follow-up study. J Affect Disord 2007;100:49–54.
77.
Donovan AL, Freudenreich O: Resolution of late-onset hypomania after repair of carotid artery stenosis: a case of vascular hypomania. J Clin Psychiatry 2007;68:798.
78.
Wijeratne C, Malhi GS: Vascular mania: an old concept in danger of sclerosing? A clinical overview. Acta Psychiatr Scand Suppl 2007;116(suppl 434):35–40.
79.
Roselló PA, Tordera TV: Bipolar disorder and subdural hematoma: difficulties for a dual diagnosis. A case report. An Psiquiatr 2007;23:356–358.
80.
Chemerinski E, Levine SR: Neuropsychiatric disorders following vascular brain injury. Mt Sinai J Med 2006;73:1006–1014.
81.
Senturk V, Bilgic A, Atbasoglu EC: A case of probable bipolar VI disorder? J Clin Psychiatry 2006;67:1309–1310.
82.
Watanabe Y, Shioiri T, Kuwabara H, Someya T: Mania after vascular dementia in a patient with bipolar II disorder. Psychiatry Clin Neurosci 2006;60:117–118.
83.
Baune BT, Adrian I, Arolt V, Berger K: Associations between major depression, bipolar disorders, dysthymia and cardiovascular diseases in the general adult population. Psychother Psychosom 2006;75:319–326.
84.
Kannan K, Tan SMK, Pillai SK, Sinniah D, Raymond AA, Hamzaini AH, Loh SF, Ismail WS, Swami V, Ruzyanie N: Bipolar mood disorder secondary to mitochondrial encephalomyopathy, lactic acidosis and stroke- like episodes (MELAS): a case report. Hong Kong J Psychiatry 2006;16:150–153.
85.
de Filippis S, Salvatori E, Bozzao A, Fantozzi LM, Martelletti P: Migraine with aura, bipolar depression, ACM aneurysm. A case report. J Headache Pain 2005;6:93–96.
86.
Heinrich TW, Junig JT: Recurrent mania associated with repeated brain injury. Gen Hosp Psychiatry 2004;26:490–492.
87.
Nilsson FM, Kessing LV: Increased risk of developing stroke for patients with major affective disorder – A registry study. Eur Arch Psychiatry Clin Neurosci 2004;254:387–391.
88.
Robinson RG: Poststroke depression: prevalence, diagnosis, treatment, and disease progression. Biol Psychiatry 2003;54:376–387.
89.
Jain S, Gibson RH, Guedet PJ, Lehrmann JA, Tsao CI: Aspiration pneumonia as a complication of severe mania. Gen Hosp Psychiatry 2003;25:136–137.
90.
Sasaki M: Organic mixed affective disorder. Ryoikibetsu Shokogun Shirizu 2003;40:180–183.
91.
Suárez-Richards M, Fournes O: Erotomania preceding an aneurysmal subarachnid haemorrhage: is there an association? J Affect Disord 2002;70:333–336.
92.
Okamoto K, Miwa H, Kamiyoshi S, Takagi R, Maeshima S, Kondo T: Recurrent unipolar depression with 48-hour cycle and the state – Dependent abnormal involuntary movements following right thalamic haemorrhage. No To Shinkei 2002;54:595–599.
93.
Varga D: Neuropsychiatric complications after stroke. Ideggyogy Sz 2002;55:128–136.
94.
Cassidy F, Carroll BJ: Vascular risk factors in late onset mania. Psychol Med 2002;32:359–362.
95.
Perez J, Tardito D: The interface between depression and cerebrovascular disease – Some hope but no hype. Clin Exp Hypertens 2002;24:639–646.
96.
Hirose T: Comorbidity in depressive disorders. Seishin Shinkeigaku Zasshi 2001;103:1046–1054.
97.
Novak-Grubic V, Tavcar R, Davis JM: Lithium intoxication secondary to unrecognized pontine haemorrhage. Acta Psychiatr Scand 2001;103:400–401.
98.
Kumar R: Lesion location in mania following stroke. Aust NZ J Psychiatry 2000;34:170.
99.
Mendez MF: Mania in neurologic disorders. Curr Psychiatry Rep 2000;2:440–445.
100.
Taha S, Diaz A, Compeyre S, Cabal P, Comoy J, Leriche B: Krouamania causing an acute subdural hematoma of arterial origin. Rev Neurol (Paris) 1999;155:1079–1081.
101.
Shulman KI, Herrmann N: Bipolar disorder in old age. Can Fam Physician 1999;45:1229–1237.
102.
Braun CM, Larocque C, Daigneault S, Montour-Proulx I: Mania, pseudomania, depression, and pseudo-depression resulting from focal unilateral cortical lesions. Neuropsychiatry Neuropsychol Behav Neurol 1999;12:35–51.
103.
Shulman KI, Herrmann N: The nature and management of mania in old age. Psychiatr Clin North Am 1999;22:649.
104.
Bakchine S: Post-lesional depression and mania. Rev Neuropsychol 1998;8:691–726.
105.
Anderson CA, Camp J, Filley CM: Erotomania after aneurysmal subarachnoid hemorrhage: case report and literature review. J Neuropsychiatry Clin Neurosci 1998;10:330–337.
106.
Kumar SK, Mahr G: CADASIL presenting as bipolar disorder. Psychosomatics 1997;38:397–398.
107.
Ghika-Schmid F, Bogousslavsky J: Affective disorders following stroke. J Eur Neurol 1997;38:75–81.
108.
Fukatsu R, Fujii T, Yamadori A, Nagasawa H, Sakurai Y: Persisting childish behavior after bilateral thalamic infarcts. Eur Neurol 1997;37:230–235.
109.
Robinson RG: Neuropsychiatric consequences of stroke. Annu Rev Med 1997;48:217–229.
110.
Robinson RG, De Carvalho ML, Paradiso S: Post-stroke neuropsychiatric problems – Diagnosis, pathophysiology and treatment. J Bras Psiquiatr 1997;46:527–534.
111.
Berthier ML, Kulisevsky J, Gironell A, Fernández Benitez JA: Post-stroke bipolar affective disorder: clinical subtypes, concurrent movement disorders, and anatomical correlates. J Neuropsychiatry Clin Neurosci 1996;8:160–167.
112.
Verdoux H, Bourgeois M: Manies secondaires à des pathologies organiques cérébrales. Ann Méd Psychol 1995;153:161–168.
113.
Tatter SB, Ogilvy CS: Recurrent manic episode 10 years after arteriovenous malformation resection. J Clin Psychiatry 1995;56:83.
114.
Evans DL, Byerly MJ, Greer RA: Secondary mania: diagnosis and treatment. J Clin Psychiatry 1995;56(suppl 3):31–37.
115.
Fujikawa T, Yamawaki S, Touhouda Y: Silent cerebral infarctions in patients with late-onset mania. Stroke 1995;26:946–949.
116.
Daum I, Ackermann H: Frontal-type memory impairment associated with thalamic damage. Int J Neurosci 1994;77:187–198.
117.
Friedman EH, Kulisevsky J, Pujol J, Berthier ML: Ballismus and mania. Neurology 1994;44:578.
118.
McGilchrist I, Goldstein LH, Jadresic D, Fenwick P: Thalamo-frontal psychosis. Br J Psychiatry 1993;163:113–115.
119.
Gnam W, Flint AJ: New onset rapid cycling bipolar disorder in an 87 year old woman. Can J Psychiatry 1993;38:324–326.
120.
Lehembre P, Graux P: Athymormia, arithmomania or stercoral compulsion in multiple infarcts of the corpus striatum. Ann Med Psychol (Paris) 1992;150:699–701.
121.
Miller BL, Mena I, Giombetti R, Villanueva-Meyer J, Djenderedjian AH: Neuropsychiatric effects of cocaine: SPECT measurements. J Addict Dis 1992;11:47–58.
122.
House A, Dennis M, Mogridge L, Warlow C, Hawton K, Jones L: Mood disorders in the year after first stroke. Br J Psychiatry 1991;158:83–92.
123.
Moskowitz AS, Altshuler L: Increased sensitivity to lithium-induced neurotoxicity after stroke: a case report. J Clin Psychopharmacol 1991;11:272–273.
124.
Berrios GE, Bakshi N: Manic and depressive symptoms in the elderly: their relationships to treatment outcome, cognition and motor symptoms. Psychopathology 1991;24:31–38.
125.
Beckson M, Cummings JL: Neuropsychiatric aspects of stroke. Int J Psychiatry Med 1991;21:1–15.
126.
Wilson D, McLaughlin T: Cerebrovascular disease and secondary mania. Gen Hosp Psychiatry 1990;12:271–275.
127.
Berthier ML, Starkstein SE, Robinson RG, Leiguarda R: Limbic lesions in a patient with recurrent mania. J Neuropsychiatry Clin Neurosci 1990;2:235–236.
128.
Robinson RG, Starkstein SE: Current research in affective disorders following stroke. J Neuropsychiatry Clin Neurosci 1990;2:1–14.
129.
Feinberg WM, Rapcsak SZ: ‘Peduncular hallucinosis’ following paramedian thalamic infarction. Neurology 1989;39:1535–1536.
130.
Bakchine S, Lacomblez L, Benoit N, Parisot D, Chain F, Lhermitte F: Manic-like state after bilateral orbitofrontal and right temporoparietal injury: efficacy of clonidine. Neurology 1989;39:777–781.
131.
Starkstein SE, Berthier ML, Lylyk PL, Casasco A, Robinson RG, Leiguarda R: Emotional behavior after a Wada test in a patient with secondary mania. J Neuropsychiatry Clin Neurosci 1989;1:408–412.
132.
Davison K: Neuropsychiatry of localized brain disorders and encephalopathies. Curr Opin Psychiatry 1989;2:76–83.
133.
Gross RA, Herridge P: A manic-like illness associated with right frontal arteriovenous malformation. J Clin Psychiatry 1988;49:119–120.
134.
Gentilini M, De Renzi E, Crisi G: Bilateral paramedian thalamic artery infarcts: report of eight cases. J Neurol Neurosurg Psychiatry 1987;50:900–909.
135.
Kwentus JA, Hart RP: Normal pressure hydrocephalus presenting as mania. J Nerv Ment Dis 1987;175:500–502.
136.
Caplan LR, Kelly M, Kase CS, Hier DB, White JL, Tatemichi T, Mohr J, Price T, Wolf P: Infarcts of the inferior division of the right middle cerebral artery: mirror image of Wernicke’s aphasia. Neurology 1986;36:1015–1020.
137.
Kahn D, Sackeim H, Malitz S: Evaluating lesion activity in manic patients. Am J Psychiatry 1984;141:1016.
138.
Scherrer P: The case of Marie-Louise N... A manic-depressive patient confined to a general hospital after a stroke followed by aphasia. Ann Med Psychol (Paris) 1982;140:530–539.
139.
Whitlock FA: The neurology of affective disorder and suicide. Aust NZ J Psychiatry 1982;16:1–12.
140.
Scherrer P, Houillon M: A manic-depressive patient isolated in a general hospital after an ictus followed by aphasia. Ann Med Psychol 1982;140:530–539.
141.
Trimble MR, Cummings JL: Neuropsychiatric disturbances following brainstem lesions. Br J Psychiatry 1981;138:56–59.
142.
Bourgeois M, Campagne A: Manic-depressive and Garcin’s syndrome. Ann Med Psychol (Paris) 1967;125(suppl 2):451–460.
143.
van der Lugt PJ, de Visser AP: Two patients with a vital expansive syndrome following a cerebrovascular accident. Psychiatr Neurol Neurochir 1967;70:349–359.
144.
Symons HS: Mania due to cerebral fat embolism following fracture of the tibia. Med J Aust 1960;47:980–981.
145.
Dunne JW, Leedman PJ, Edis RH: Inobvious stroke: a cause of delirium and dementia. Aust NZ J Med 1986;16:771–778.
146.
McDonald WM: Epidemiology, etiology, and treatment of geriatric mania. J Clin Psychiatry 2000;61(suppl 13):3–11.
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