This study was designed to evaluate functional status at a 1-year follow-up in consecutive first-stroke patients after discharge from rehabilitation hospital and to identify reliable prognostic factors associated with changes in their abilities. Functional evaluation was made of consecutive patients 1 year after discharge to their own homes. Two multiple logistic regressions (forward stepwise) were performed using both improvement and worsening of the Barthel Index score between discharge and follow-up as dependent variables. Independent variables were medical, demographic and social factors. The final sample included 157 out of 172 patients. During the follow-up, 10 patients (5.81%) died because of a new cerebrovascular event, 1 patient died of myocardial infarction, 2 patients had new strokes and 2 fractured their paretic legs. Functionally, 43.3% of the patients maintained the level they achieved during inpatient rehabilitation treatment, 23.6% improved and the remaining 33.1% worsened. Patients with hemineglect and aged ≥65 years had a higher probability of functional worsening (odds ratio, OR = 3.77, 95% confidence interval, CI = 1.42– 10.0 and OR = 3.93, 95% CI = 1.72–8.95, respectively). Postdischarge rehabilitation (performed for 46.5% of the final sample) was significantly and positively associated with functional improvement (OR = 7.23, 95% CI = 2.89–18.05), and its absence with functional worsening (OR = 12.32, 95% CI = 4.47–37.01). In conclusion, in nearly half of the cases, functional status was still not stabilized at the time of discharge from the rehabilitation hospital. Postdischarge outpatient treatment was useful for preventing worsening of the functional ability achived during inpatient treatment and increased the possibility of further functional improvement. Age ≥65 years and hemineglect were predictors of functional worsening at follow-up.

1.
Wade DT: Neurological rehabilitation. Curr Opin Neurol Neurosurg 1992;5:667–668.
2.
Chan L, Koepsell TD, Deyo RA, Esselman PC, Haselkorn JK, Lowery JK, Stolov WC: The effect of Medicare’s payment system for rehabilitation hospitals on length of stay, charges, and total payments. N Engl J Med 1997;337:978–985.
3.
Andrews K, Brocklehurst JC, Richards B, Laycock PJ: The rate of recovery from stroke and its measurements. Int Rehabil Med 1981;3:155–161.
4.
Dombovy ML, Basford JL, Whisnant JP, Bergstralh EJ: Disability and use of rehabilitation services following stroke in Rochester, Minnesota, 1975–1979. Stroke 1987;18:830–836.
5.
Garraway WM, Akthar AJ, Hockey L, Prescott RJ: Management of acute stroke in the elderly: Follow-up of a controlled trial. BMJ 1980;281:827–829.
6.
Kotila M, Waltimo O, Niemi ML, Laaksonen R, Lempinen M: The profile of recovery from stroke and factors influencing outcome. Stroke 1994;15:1039–1044.
7.
Thorngren M, Westling B, Norrving B: Outcome after stroke in patients discharged to independent living. Stroke 1990;21:236–240.
8.
Johnston MV, Kirshblum S, Zorowitz RM, Shiflett SC: Prediction of outcomes following rehabilitation of stroke patients. Neurorehabilitation 1992;2:72–97.
9.
Davidoff G, Keren O, Ring H, Solzi P: Long-term effects of rehabilitation and maintenance of gains. Arch Phys Med Rehabil 1991;72:869–873.
10.
Dam M; Tonin P, Casson S, Ermani M, Pizzolato G, Battistin L: The effects of long-term rehabilitation therapy on poststroke hemiplegic patients. Stroke 1993;24:1186–1191.
11.
Ferrucci L, Bandinelli S, Guralnik JM, Lamponi M, Bertini C, Falchini M, Baroni A: Recovery of functional status after stroke. A postrehabilitation follow-up study. Stroke 1993;24:200–205.
12.
Tangeman PT, Banaitis DA, Williams AK: Rehabilitation of chronic stroke patients: Changes in functional performance. Arch Phys Med Rehabil 1990;71:876–880.
13.
Werner RA, Kessler S: Effectiveness of an intensive outpatient rehabilitation program for postacute stroke patients. Am J Phys Med Rehabil 1996;75:114–120.
14.
Foulkes MA, Wolf PA, Price TR, Mohr JP, Hier DB: The Stroke Data Bank: Design, methods, and baseline characteristics. Stroke 1988;19:547–554.
15.
Mahoney F, Barthel DW: Functional evaluation: The Barthel Index. Md State Med J Rehabil 1965;14:61–65.
16.
Wade DT, Wood VA, Hewer RL: Functional abilities after stroke: Measurement, natural history and prognosis. J Neurol Neurosurg Psychiatry 1987;50:177–182.
17.
Kertesz A: Aphasia and Associated Disorders: Taxonomy, Localization and Recovery. New York, Grune and Stratton, 1979.
18.
Pizzamiglio L, Judica A, Razzano C, Zoccolotti P: Toward a comprehensive diagnosis of visual-spatial disorders in unilateral brain-damaged patients. Psychol Assess 1989;5:199–218.
19.
Pizzamiglio L, Antonucci G, Judica A, Montenero P, Razzano C, Zoccolotti P: Cognitive rehabilitation of the hemineglect disorder in chronic patients with unilateral brain damage. J Clin Exp Neuropsychol 1992;14:901–923.
20.
Basso A: Approaches to neuropsychological rehabilitation: Language disorders; in Meyer MJ, Benton AL, Diller L (eds). Neuropsychological Rehabilitation. Edinburgh, Churchill Livingstone, 1989 pp 294–314.
21.
Formisano R, Barbanti P, Catarci T, De Vuono G, Calisse P, Razzano C: Prolonged muscular flaccidity: Frequency and association with unilateral spatial neglect after stroke. Acta Neurol Scand 1993;88:313–315.
22.
Chamie M: What does morbidity have to do with disability? Disabil Rehabil 1995;17:323–327.
23.
Denes F, Semenza C, Stoppa E, Lis A: Unilateral spatial neglect and recovery from hemiplegia – A follow up study. Brain 1982;105:543–552.
24.
Paolucci S, Antonucci G, Emberti Gialloreti L, Traballesi M, Lubich S, Pratesi L, Palombi L: Predicting stroke in patient rehabilitation outcome: The prominent role of neuropsychological disorders. Eur Neurol 1996;36:385–390.
25.
Paolucci S, Antonucci G, Pratesi L, Traballesi M, Lubich S, Grasso MG: Functional outcome in stroke inpatient rehabilitation: Predicting no, low and high response patients. Cerebrovasc Dis 1998;8:228–234.
26.
Gainotti G: Les manifestations de néglicence et d’inattention pour l’hémispace. Cortex 1968;4:64–91.
27.
Zoccolotti P, Antonucci G, Judica A, Montenero P, Pizzamiglio L, Razzano C: Incidence and evolution of the hemineglect disorder in chronic patients with unilateral right brain damage. Int J Neurosci 1989;47:209–216.
28.
Zarit SH, Khan RL: Impairment and adaptation in chronic disabilities: Spatial inattention. J Nerv Ment Dis 1974;159:63–72.
29.
Antonucci G, Guariglia C, Judica A, Magnotti L, Paolucci S, Pizzamiglio L, Zoccolotti P: Effectiveness of neglect rehabilitation in a randomized group study. J Clin Exp Neuropsychol 1995;17:383–389.
30.
Whurr R, Lorch MP, Nye C: A meta-analysis of studies carried out between 1946 and 1988 concerned with the efficacy of speech and language therapy treatment for aphasic patients. Eur J Disord Commun 1992;27:1–17.
31.
Paolucci S, Silvestri G, Lubich S, Pratesi L, Traballesi M, Gigli GL: Poststroke late seizures and their role in rehabilitation of inpatients. Epilepsia 1997;38:266–270.
32.
Wilterdink JL, Easton JD: Vascular event rates in patients with atherosclerotic cerebrovascular disease. Arch Neurol 1992;49:857–863.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.