Since September 1987, all patients under 46 years admitted to our Hospital with cerebral infarcts (CI), the cause of which was unknown, have undergone complete hematological screening (partial thromboplastin time; Prothrombin ratio; flbrinogen level; lupus anticoagulant activity; fibrinolytic capacity; proteins C and S; antithrombin III; AT-III, and hemoglobin electrophoresis when indicated). In 2 out of 22 patients admitted in 1988, sickle cell trait and AT-III deficiency were the only abnormalities identified. We conclude that complete hematological screening should be carried out in every young patient with CI when more common causes are not present.

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