... therapy alone. Treatment with sonic hedgehog pathway inhibitors (vismodegib, sonidegib) is designed to inhibit key signaling proteins and gene pathways involved with BCC to reduce the uncontrolled proliferation of basal cells in complicated disease and can be invaluable in treating patients with advanced...

.... Additionally, there is no consistently recognized treatment for MRH described in the literature. The rarity of the disease contributes to the difficulty in defining a standardized treatment. We present the case of a patient with extensive joint and skin involvement who was successfully treated with infliximab...

... to treat the patient with ixekizumab, an anti-IL-17 antibody known for its rapid action in psoriasis vulgaris, that has also been reported as effective in GPP. The patient improved rapidly, with resolution of the active lesions after the first administration. The treatment has been continued for 2 years...

..., and nondermatologic involvements like neurological and renal disorders. We report a case series of the data regarding the characteristics and treatment of 14 patients diagnosed with scleromyxedema and their follow-up. Patients entered the study based on scleromyxedema diagnosis criteria. Comorbidities were also...

...Kathryn J. Golden; Ryan M. Diana This case report discusses the treatment of brachioradial pruritus (BRP) in a 57-year-old white male veteran with chiropractic and acupuncture. The patient presented with findings consistent with a diagnosis of BRP to include sharp pain, burning, and itching...

... years after that treatment. Dental silicon casts are a novel technique for an appropriate fixation over auricles in the treatment of APs and had an effective therapeutic result in our case. [email protected] 27 01 2021 18 03 2021 9 7 2021 © 2021 The Author(s). Published...

... general health. Topical corticosteroids were the mainstay of treatment. AR-EAC is a benign disorder, the nature of which remains enigmatic. [email protected] 18 02 2021 18 03 2021 10 6 2021 © 2021 The Author(s). Published by S. Karger AG, Basel 2021 Open Access...

.... In this case report, we show our experience with an adolescent patient with a long history of generalized and refractory vitiligo, for which treatment with topical tofacitinib, a JAK inhibitor, associated with phototherapy for 9 months, resulted in near complete repigmentation. sineidaferreira...

... a nasolabial flap. A 66-year-old female was referred to the Department of Plastic and Reconstructive Surgery to receive treatment for a cutaneous tumor on her right lateral nose wall, which had been growing rapidly for 3 months. Histological analysis of a biopsy specimen of the tumor suggested...

.... Microwaves have had limited uses for medical purposes. Recently a new portable microwave device has been approved for the treatment of skin lesions. Prior research has demonstrated immuno-stimulatory effects against HPV infection. We report the application of a novel portable medical microwave unit to treat...

...Aslı Bilgiç Temel; Cumhur Ibrahim Bassorgun; Ayşe Akman-Karakaş; Erkan Alpsoy; Soner Uzun Omalizumab is a humanized monoclonal antibody which is an FDA-approved treatment of severe allergic asthma and inhibits IgE binding to FcεRI. According to increasing evidence of IgE inhibition, omalizumab...

...Alicia Sfecci; Camille Orion; Laure Darrieux; Laurent Tisseau; Gilles Safa Darier disease (DD) is a rare dominantly inherited genodermatosis characterized by loss of intercellular adhesion (acantholysis) and abnormal keratinization. DD is often difficult to manage. Numerous treatments have...

...Yasir Azim Mirza; Davide Altamura; Torkan Hirbod; Roberto Verdolini Classic Kaposi's sarcoma (KS) is a disease with low mortality but high morbidity. The optimum treatment of KS depends upon several factors, including location of lesions, disease progression, severity of symptoms and patient...

... intravenous immune globulin in pyoderma gangrenosum. J Am Acad Dermatol 1995;32:140-142. 3. Cummins DL, Anhalt GJ, Monahan T, Meyerle JH: Treatment of pyoderma gangrenosum with intravenous immunoglobulin. Br J Dermatol 2007;157:1235-1239. 4. Dirschka T, Kastner U, Behrens S, Altmeyer P: Successful...

...Tomoko Shima; Yuki Yamamoto; Takaharu Ikeda; Fukumi Furukawa There are several treatment methods for localized scleroderma, but treatment is difficult when the lesion is widely distributed. We encountered a case who was treated successfully with etretinate, a vitamin A derivative. The usefulness...

...N. Irla; T. Schneiter; E. Haneke; N. Yawalkar Background: Etanercept is a fully human tumor necrosis factor α receptor fusion protein that binds tumor necrosis factor α with greater affinity than natural receptors. Biologics are widely used in the treatment of psoriasis and psoriasis arthritis...

...Tomoko Rind; Naoki Oiso; Akira Kawada Anogenital warts are an infectious disorder of the anogenital lesion caused by one or more human papilloma viruses. Verruca is commonly treated with freezing with liquid nitrogen, laser therapy or application of imiquimod. Such ablative treatment may cause pain...