For the purposes of surgical indications and considerations, we prefer that the general, anatomical term ‘pineal tumors’ be used for all tumors in the region of the pineal gland, and that such developmental, histological, or congenital terms as dysgerminoma, pinealoma, and teratoma be reserved exclusively for neuropathological descriptive purposes. Of our 26 children – age range from 7 months to 16 years – treated for pineal tumors during the 9-year period 1972–1980 inclusive, all presented with hydrocephalus necessitating ventriculoperitoneal shunts. This incidence of pineal tumors represents 9.4% of the total number of brain tumors in childhood (275) which were managed by the senior author during this period of time. 23 of the 26 children were operated for direct attack of the tumor, with the postoperative mortality being 1 (as defined by death preceding discharge from hospital): a 7-month-old child with a medulloepithelioma which rapidly, within 3 weeks, invaded the thalamus, corpus callosum, brain stem, and cerebellum, causing death. It is recommended that cerebral spinal fluid (CSF) be taken from the ventricular system at the time of insertion of the ventriculoperitoneal shunt and that this fluid be analyzed for alpha-fetoprotein (AFP), human chorionic gonadotrophins (HCG), and carcinoembryonic antigen (CEA), and that cytology be performed to search for neoplastic cells. If the marker studies are positive, or malignant neoplastic cells identified at cytology, then it is recommended that Roentgen therapy be given to the patient and that no direct surgical attack of the tumor be attempted. On the other hand, if the marker studies and cytology are negative, direct surgical attack is recommended after the ventriculoperitoneal shunt, when all signs of an increase in intracranial pressure disappear. None of our patients had steroid management for the increase in intracranial pressure. The shunt sufficed. We suggest that the surgical approach (parasagittal, occipital-transtentorial, suboccipital-supracerebellar) be planned on the basis of the direction of displacement of the Galenic (internal cerebral vein, and great vein of Galen) and supraculminate (pre-central and superior cerebellar) venous systems: (1) when the Galenic system is displaced inferiorly, a parasagittal approach is recommended; (2) when the Galenic system is displaced superiorly, a suboccipital supracerebellar approach is recommended; (3) when the supraculminate system is displaced posteriorly, an occipital transtentorial approach is recommended.

This content is only available via PDF.
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.