...: Tumor samples from patients without pathological complete response (non-pCR) were evaluated. Pathological complete response (pCR) was defined as no invasive tumor in breast and lymph nodes (ypT0/is ypN0). HR and HER2 status determined before NAC was compared with the corresponding receptor status...

..., a pathological complete response (pCR) has been described as generally resulting in a favorable prognosis. However, there are subgroups, such as patients with a mutation in BRCA1 or BRCA2 ,in which the effect of pCR on the prognosis is suspected to be weaker. Patients with a family history of breast...

... or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Breast cancer Neoadjuvant treatment Pathological complete response...

... and, therefore, enables a breast-conserving surgery. Furthermore, it allows monitoring of therapy response. In particular, in HER2-positive and triple-negative breast cancer (TNBC) the achievement of a pathological complete response (pCR) is associated with a favorable long-term survival [ 20 ]. However...