Background: Breast cancer is a public health problem and it is the most common gynecologic neoplasia worldwide. The risk factors for its development are of both hereditary and environmental origin. Certain foods have been clearly associated with modifying the breast cancer risk. The aim of the present analysis was to evaluate the effects of cow's milk and meat consumption on the development of breast cancer in a population from Western Mexico (Colima). Material and Methods: We studied 97 patients presenting with a histopathologic diagnosis of breast cancer and 104 control individuals who did not present with the disease (Breast Imaging Report and Data System (BI-RADS) 1-2). 80% of the population belonged to a low socioeconomic stratum. The main clinical characteristics were analyzed along with the lifetime consumption of meat and milk. Results: High milk consumption increased the breast cancer risk by 7.2 times (p = 0.008) whereas the consumption of meat was not significantly associated with the disease. Conclusions: High consumption of cow's milk was a risk factor for the development of breast cancer. Further studies are needed to evaluate the effects of dietary patterns on the development of breast cancer in diverse populations with ethnic, cultural, and economic differences.

Keywords:
Breast cancer, Risk factors, Tumorigenesis
1.
Arce C et al.: Cáncer de mama. Cancerología 2011;6:77-86.
2.
Cárdenas-Sánchez J, Erazo-Valle A, Maafs-Molina E: Consenso Nacional sobre diagnóstico y tratamiento del cáncer mamario, ed 4. Rio de Janeiro, Elsevier, 2011, pp 6-8.
3.
Guliano A, Hurvitz S: Trastornos de las mamas; Papadakis M, McPhee SJ, eds : Diagnóstico Clínico y Tratamiento, ed 50. New York, McGraw-Hill 2012, pp 697-698.
4.
Macon MB, Fenton SE: Endocrine disruptors and the breast: early life effects and later life disease. J Mammary Gland Biol Neoplasia 2013;18:43-61.
5.
De Stefani E, Boffetta P, Ronco AL, Deneo-Pellegrini H, Correa P, Acosta G, Mendilaharsu M, Luaces ME, Silva C: Processed meat consumption and risk of cancer: a multisite case-control study in Uruguay. Br J Cancer 2012;107:1584-1588.
6.
Karimi Z, Jessri M, Houshiar-Rad A, Mirzaei HR, Rashidkhani B: Dietary patterns and breast cancer risk among women. Public Health Nutr 2014;17:1098-1106.
7.
Fung TT, Hu FB, Holmes MD, Rosner BA, Hunter DJ, Colditz GA, Willett WC: Dietary patterns and the risk of postmenopausal breast cancer. Int J Cancer 2005;116:116-121.
8.
Torres-Sánchez L, Galván-Portillo M, Lewis S, Gómez-Dantés H, López-Carrillo L: Diet and breast cancer in Latin-America. Salud Publica Mex 2009;51(suppl 2):S181-S190.
9.
Voguel V: Epidemiologia del cáncer de mama; in Bland KI, Copeland EM, eds: La Mama, Manejo Multidisciplinario de las Enfermedades Benignas y Malignas, ed 3. Buenos Aires, Médica Panamericana, 2007, pp 355-366.
10.
Missmer SA, Smith-Warner SA, Spiegelman D, Yaun SS, Adami HO, Beeson WL, van den Brandt PA, Fraser GE, Freudenheim JL, Goldbohm RA, Graham S, Kushi LH, Miller AB, Potter JD, Rohan TE, Speizer FE, Toniolo P, Willett WC, Wolk A, Zeleniuch-Jacquotte A, Hunter DJ: Meat and dairy food consumption and breast cancer: a pooled analysis of cohort studies. Int J Epidemiol 2002;31:78-85.
11.
Hjartåker A, Laake P, Lund E: Childhood and adult milk consumption and risk of premenopausal breast cancer in a cohort of 48,844 women - the Norwegian women and cancer study. Int J Cancer 2001;93:888-893.
12.
Hanf V, Körner W: Consumption of cow's milk and possible risk of breast cancer. Breast Care 2010;5:44-45.
13.
Dong JY, Zhang L, He K, Qin LQ: Dairy consumption and risk of breast cancer: a meta-analysis of prospective cohort studies. Breast Cancer Res Treat 2011;127:23-31.
14.
Moorman PG, Terry PD: Consumption of dairy products and the risk of breast cancer: a review of the literature. Am J Clin Nutr 2004;80:5-14.
15.
Parodi PW: Dairy product consumption and the risk of breast cancer. J Am Coll Nutr 2005;24(6 suppl): 556S-568S.
16.
Zhang J, Kesteloot H: Milk consumption in relation to incidence of prostate, breast, colon, and rectal cancers: is there an independent effect? Nutr Cancer 2005;53:65-72.
17.
Institute of Grocery Distribution: Portion Size: A Review of Existing Approaches. Watford, Institute of Grocery Distribution, 2008.
18.
Medina-Mora MA, Peña-Corona MP, Cravioto P, Villatoro J, Kuri P: Del tabaco al uso de otras drogas: el uso temprano de tabaco aumenta la probabilidad de usar otras drogas. Salud Publica Mex 2002;44:S109-S115.
19.
Domingo JL: Nutrients and chemical pollutants in fish and shellfish. Balancing health benefits and risks of regular fish consumption. Crit Rev Food Sci Nutr 2014, in press. DOI: 10.1080/10408398.2012.742985
20.
Zhu H, Yang X, Zhang C, Zhu C, Tao G, Zhao L, Tang S, Shu Z, Cai J, Dai S, Qin Q, Xu L, Cheng H, Sun X: Red and processed meat intake is associated with higher gastric cancer risk: a meta-analysis of epidemiological observational studies. PLoS One 2013;8:e70955.
21.
Drewnowski A, Hann C: Food preferences and reported frequencies of food consumption as predictors of current diet in young women. Am J Clin Nutr 1999;70:28-36.
22.
Steyn NP, Labadarios D, Nel JH: Factors which influence the consumption of street foods and fast foods in South Africa - a national survey. Nutr J 2011;10:104.
23.
World Health Organization: Cancer de mama: prevención y control. www.who.int/topics/cancer/breastcancer/ es/index1.html.
24.
dos Santos Silva I: Cancer Epidemiology: Principles and Methods. Lyon, IARC Press, 1999.
25.
LaMorte WW, Sullivan L: Confounding and effect measure modification. Boston University School of Public Health, http://sphweb.bumc.bu.edu/otlt/MPH-Modules/BS/BS704-EP713_Confounding-EM/BS704-EP713_Confounding-EM7.html, 2014.
26.
Farlow DW, Xu X, Veenstra TD: Quantitative measurement of endogenous estrogen metabolites, risk factors for development of breast cancer, in commercial milk products by LCMS/MS. J Chromatogr B Analyt Technol Biomed Life Sci 2009;877:1327-1334.
27.
Rossi RE, PericleousM, Mandair D, Whyand T, Caplin ME: The role of dietary factors in prevention and progression of breast cancer. Anticancer Res 2014;34:6861-6875.
28.
Hanf V, Gonder U: Nutrition and primary prevention of breast cancer: foods, nutrients and breast cancer risk. Eur J Obstet Gynecol Reprod Biol 2005;123:139-149.
29.
Bernier MO, Plu-Bureau G, Bossard N, et al.: Breastfeeding and risk of breast cancer: a metaanalysis of published studies. Hum Reprod Update 2000;6:374-386.
30.
Faupel-Badger JM, Arcaro KF, Balkam JJ, et al.: Postpartum remodeling, lactation, and breast cancer risk: summary of a National Cancer Institute-sponsored workshop. J Natl Cancer Inst 2013;105:166-174.
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2015
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