This article summarizes the contents of posters which were presented at the San Antonio Breast Cancer Symposium in sessions dealing with familial breast cancer,prevention, risk factors and genetics. Genetic testing for inherited or high-risk breast cancer was one of the main topics, focusing on the genetic counseling in women with hereditary breast cancer from different social and ethnic backgrounds. Information and training in breast self-awareness are important factors for reducing cancer anxiety. In mice, chemoprevention in breast cancer using retinoids showed to be effective by reducing tumor multiplicity. Vitamin A derivatives and COX 2 inhibitors could be potentially used to prevent breast cancer in woman at increased risk. Inhibition of EGFR (epidermal growth factor receptor) kinase reduces tumor multiplicity and could re-sensitize tumors to taxane chemotherapy. Analysis of histological subtypes of breast cancer demonstrated differences in DNA methylation and molecular marker expression. Lifestyle, e.g. oral contraception or hormone replacement therapy, is affecting patients at both basic and high risk of developing breast cancer.

This content is only available via PDF.
2006
Copyright / Drug Dosage / Disclaimer
Copyright: All rights reserved. No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.
Drug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. However, in view of ongoing research, changes in government regulations, and the constant flow of information relating to drug therapy and drug reactions, the reader is urged to check the package insert for each drug for any changes in indications and dosage and for added warnings and precautions. This is particularly important when the recommended agent is a new and/or infrequently employed drug.
Disclaimer: The statements, opinions and data contained in this publication are solely those of the individual authors and contributors and not of the publishers and the editor(s). The appearance of advertisements or/and product references in the publication is not a warranty, endorsement, or approval of the products or services advertised or of their effectiveness, quality or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements.
You do not currently have access to this content.