...Yupei Li; Xinyao Luo; Mei Yang; Baihai Su Oxidative stress is prevalent in end-stage kidney disease patients receiving chronic hemodialysis and is associated with heavy cardiovascular disease burdens and increased mortality risks. Hemoincompatible hemodialysis membranes per se contribute...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. 2023 Leukocytes ER stress JNK Apoptosis Autophagy Uremia Uremic toxins Protein carbonyls Oxidative stress...

... not statistically different for the 2 types of dialysis membranes. Conclusions: MCO membrane was superior to HF membrane in the removal of cytokines in septic patients with AKI. However, a similar effect was not observed for oxidative stress markers. This prospective study was conducted in the Internal Diseases...

...Takeshi Shigematsu; Takahiro Kuragano; Takenobu Kamimura; Sayuri Kawada; Rie Imamura; Yoshihiko Nishian; Miki Miyamoto; Takashi Miyamoto; Takeshi Nakanishi Background/Aim: In this study, we compared the dialysis efficiency, oxidative stress, and nutritional conditions between predilution on-line...

...-flux membrane High cut-off membrane Cytokines Oxidative stress Acute kidney injury (AKI) requiring renal replacement therapy (RRT) occurs in 5–6% of critically ill patients and is associated with high mortality and significant health resource utilization [ 1-5 ]. Currently available...

...-analysis of RCTs comparing ViE-m to conventional HD. Endpoints of interest were a series of biomarkers pertaining to anemia status, inflammation, oxidative stress and dialysis efficacy/status. Results: Sixty studies were included. ViE-m significantly improved the Erythropoietin Resistance Index but had...

... or safety. The publisher and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Chronic kidney disease Dialysis Oxidative stress Free radicals The prevalence...

... and increased oxidative stress are underlying the uremia-associated immune deficiency. Summary: In this review, the differential impact of uremia on the cellular immune system is summarized. Virtually all immune cells studied show a combination of an activated status and loss of function. However, uremia...

..., Kossari N, Guérin A, Geffroy S, Delavaud G, Marin-Esteban V, Glotz D, Charron D, Toubert A: Oxidative stress mediates a reduced expression of the activating receptor NKG2D in NK cells from end-stage renal disease patients. J Immunol 2009;182:1696-1705. The NK cell compartment represents about 10...

... and other biomolecules such as unsaturated lipids [ 52 ]. The development of unbiased analytical techniques is a prerequisite to future and reliable investigation of NO and HSA-SNO in CKD and other human diseases associated with oxidative stress and modified HSA levels/function. Unfortunately...

...Silvia D. Rodrigues; Giuseppe B. Batista; Max Ingberman; Roberto Pecoits-Filho; Lia S. Nakao Background/Aims: Oxidative stress has been considered a nontraditional risk factor for cardiovascular disease in the chronic kidney disease (CKD) population, possibly triggered by uremic toxicity. Methods...

... is associated with oxidative stress on the leukocyte membrane due to the HD process. Methods: Expressions of Cu/Zn-SOD mRNA in leukocytes, contents of plasma SOD, and malondialdehyde (MDA) in leukocyte and erythrocyte membranes, respectively, were examined in 25 HD patients and 14 healthy volunteers. These were...

... as described by Witko-Sarsat et al. [ 4 ] using spectrophotometry on a microplate reader. Concentrations of AOPP are expessed in µ M /l of chloramine-T equivalent. Peritoneal dialysis Hemodialysis Oxidative stress Nitrosative stress Chronic renal failure Increased oxidative stress has been...

.... Acute kidney injury Hemofiltration Interleukin-6 Oxidative stress Sepsis Polysulfone Sieving coefficient High cut-off membrane In spite of recent progress in critical care medicine, mortality of severe sepsis and septic shock still remains high [ 1 ]. Many critically ill patients...

... in patients with SAS, oxidative stress has been suggested to play a major role. In patients with SAS, the repetitive ischemia-reperfusion state causes excessive production of oxygen free radicals and may subsequently lead to oxidative injury of various biomolecules. Due to the high prevalence of SAS...

... (HD) patients. However, it is unclear whether increasing dialysate purity affects chronic inflammation, oxidative stress, and lipid abnormalities. Methods: In a prospective cohort study, 126 patients undergoing maintenance HD using conventional dialysate (CD) with one endotoxin cut filter were...

... dialysate, tested ex vivo on cultured MC, induced oxidative stress (+39%, p < 0.01), slowed their proliferation (–20%, p < 0.01), and stimulated MCP-1 synthesis (+46%, p < 0.01). Iron content in MCs exposed to dialysate obtained after IS infusion was increased by 32% (p < 0.01). Conclusion...

... individuals. Methods: Total antioxidant capacity (TAC), antioxidants, i.e., superoxide dismutase (SOD) glutathione peroxidase (GPX), reduced glutathione (GSH) and catalase, and biomarkers of oxidative stress were evaluated in plasma, whole blood and lymphocytes. Results: The study showed decreased plasma TAC...

...Tomoko Sakata; Ryuichi Furuya; Takako Shimazu; Mari Odamaki; Sakae Ohkawa; Hiromichi Kumagai Background: Increased oxidative stress is associated with various complications in hemodialysis (HD) patients. Methods: We examined the effect of coenzyme Q10 (CoQ10) administration on the plasma oxidative...

...Marion Morena; Valérie Gausson; Nadya Mothu; Jean-Louis Bouchet; Monique Chanas; Mireille Grandvuillemin; Alain Robert; Carlos Vela; Bernard Canaud; Jean-Paul Cristol; Michel Olmer Background/Aims: This study aimed at evaluating oxidative stress (OS) markers (i) in a cross-sectional study...