...: For in vitro testing of the removal of protein-bound substances, whole blood and plasma were spiked with uremic retention solutes (homocysteine, hippuric acid, indoxyl sulfate, 3-carboxy-4-methyl-5-propyl-2-furanpropionic acid) and the toxins of liver failure (bilirubin, cholic acid, tryptophan, phenol...

...Anis Chaba; Stephen Warrillow; Caleb Fisher; Akinori Maeda; Sofia Spano; Rinaldo Bellomo Introduction: Liver failure is a life-threatening condition characterized by the accumulation of metabolic toxins. Extracorporeal albumin dialysis (ECAD) has been promoted as a possible therapy. Methods: We...

... with 312 appropriate for assessment and 28 studies meeting eligibility criteria. Most of the studies were case reports. Hyperammonemia was typically secondary to inborn errors of metabolisms in children and to liver failure in adult patients. Ammonia clearance was most commonly reported during continuous...

...Johannes Holle; Alexander Gratopp; Sophie Balmer; Verena Varnholt; Stephan Henning; Philip Bufler; Dominik Müller; Leonard Rosenfeld Background and Aims: Acute and acute on chronic liver failure are life-threatening conditions, and bridging to transplantation is complicated by a paucity of suitable...

... are mainly protein-bound [ 3, 6 ]. Liver failure (LF) is characterized by the release of toxic molecules accumulating in the blood, potentially causing cellular damage and eventually leading to multi-organ dysfunction [ 1 ]. The most widely studied hepatic toxin is bilirubin that is differentiated...

... with or without acute kidney injury, include liver failure, rhabdomyolysis, severe autoimmune exacerbations and poisonings. In this article, we discuss some of the basic principles involved in sorbent technology, and how these may contribute to treatment efficacy, review the actual experiences with CPFA...

... or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Blood purification Liver failure Plasmapheresis Sepsis Adsorption Artificial liver support Extracorporeal blood purification (EBP) is used to ‘clean' blood from endogenous...

... dialysis Plasma separation Liver failure Adsorption Artificial liver support The liver plays critical roles in the maintenance of homeostasis and metabolic balance, and thus, the impairment of liver function below a critical level leads to lethal complications, such as encephalopathy...

..., instructions or products referred to in the content or advertisements. Albumin dialysis Fractionated plasma separation and adsorption dialysis Liver failure Copper Liver transplantation Case Report Blood Purif 2009;28:102 107 DOI: 10.1159/000218090 Received: October 24, 2008 Accepted: February 17...

... responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Prometheus ® Fractionated plasma separation and adsorption Artificial liver support Liver failure Renal failure Hepatorenal syndrome...

... dialyzers and adsorption columns during a single 6-hour treatment. Methods: Nine patients with acute on chronic liver failure were included (6 females, age 49 ± 4 years). Levels of endogenous toxins (urea nitrogen [UN, mg/dl], creatinine [Cr, mg/dl], total bilirubin [tB, mg/dl], and bile acids [BA, µmol/l...

.... Wilson’s disease Molecular adsorbent recirculating system Liver failure Original Paper Blood Purif 2003;21:232 236 DOI: 10.1159/000070695 Accepted: February 6, 2003 Liver Support A Task for Nephrologists? Extracorporeal Treatment of a Patient with Fulminant Wilson Crisis Tanja Manza Andreas Ochsb...

... and the editor(s) disclaim responsibility for any injury to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. Liver failure Albumin dialysis Albumin-bound toxins Original Paper Blood Purif 2003;21:244 252 DOI: 10.1159...

...Rajiv Jalan; Roger Williams The vast majority of patients that are referred to a specialist hepatological centre suffer from acute deterioration of their chronic liver disease. Yet, this entity of acute-on-chronic liver failure remains poorly defined. With the emergence of newer liver support...