... to persons or property resulting from any ideas, methods, instructions or products referred to in the content or advertisements. The oXiris membrane (Baxter, IL, USA) is a heparin-coated haemofilter suitable for continuous renal replacement therapy. Interestingly, this device can also be used...

... with heparin-coated or uncoated PMX-F for 2 h at 37°C. Cytokines were quantitated by multiplex bead array assay or ELISA. Results: Interleukin (IL)-8, RANTES, platelet-derived growth factor-bb, and transforming growth factor-β were substantially adsorbed onto PMX-F without heparin coating. The adsorbed...

... therapy. This study tested the effect of citrate compared with acetate on heparin avoidance and other parameters. Methods: Sixty-one chronic hemodialysis (HD) patients were switched from conventional dialysis fluid (acetate) to citrate dialysis fluid and were treated in 3 phases, each lasting 4 weeks: 50...

... at each separate period of investigation. An increasing number of patients over time needed additional tinzaparin to each citrate HD to perform uninterrupted dialyses Biocompatibility Blood purification Citrate Haemodialysis Haemoglobin Heparin Standard haemodialysis (HD) is performed...

.... No previous study has sought to summarize existing evidence on the use of taurolidine-citrate locks. A systematic review and meta-analysis were undertaken to determine whether taurolidine-citrate was more effective than heparin in the prevention of CRB. Methods: The major English (PubMed, EBSCO, Web...

...Solbjørg Sagedal; Bartlomiej J. Witczak; Kåre Osnes; Anders Hartmann; Ingrid Os; Lars Eikvar; Olav Klingenberg; Frank Brosstad Background: We investigated whether the heparin-coated AN69 ST hemodialysis (HD) filter induced less hypercoagulability during HD than a conventional polysulfone filter (F...

...Heleen M. Oudemans-van Straaten Background: Heparins are used for circuit anticoagulation during continuous renal replacement therapy (CRRT). Because heparins cause systemic anticoagulation, they increase the risk of bleeding. Citrate provides regional anticoagulation. Since citrate is a buffer...

...Ralph J. Caruana; Michael C. Smith; David Clyne; James W. Crow; Jacqueline M. Zinn; Jane Hall Diehl We performed a controlled parallel study comparing the effects of heparin sodium to epoprostenol sodium (prostacyclin sodium, Flolan®) during hemodialysis in 30 dialysis patients. Mean fiber bundle...

...G. Zobel; M. Trop; W. Muntean; E. Ring; H. Gleispach Continuous arteriovenous hemofiltration requires continuous anticoagulation to prevent early hemofilter clotting. We used heparin given continuously in the arterial line of the extracorporeal circuit as anticoagulant in children with initially...

...Suhail Ahmad; Kiang-Teck Yeo; William M. Jensen; Del Landicho; Barbara Gregory; Judith L. Moritz; Margaret Kenny Citrate anticoagulation has been used as an alternative to heparin for hemodialysis in high-risk patients; however, its use in hemofiltration has not been well studied. We examined...

...Katharina Kodras; Thomas Benesch; Irmgard Neumann; Martin Haas Background: Heparin-free dialysis (HFD), i.e. only priming of the dialyser and no systemic heparinization, might reduce the risk of bleeding in dialysis patients receiving oral anticoagulation. The efficacy of HFD with two different...

... the safety of anticoagulants other than NM, from the perspective of bradykinin production and the consequent drop in blood pressure during treatment. Methods: For each of 10 patients with ulcerative colitis, we used four types of anticoagulants sequentially [NM (30–50 mg), heparin, low-molecular-weight...

...-hour duration. Fifty-six percent of the time, a mean heparin bolus of 29 units/kg resulted in subtherapeutic activated clotting times. Mean heparin infusion rates of 35 units of heparin/kg/h achieved effective anticoagulation. A calcium infusion rate of 0.11 ± 0.05 mmol/kg/h avoided hypocalcemia. One...

... studies, 16 and 15 patients with acute renal failure during critical illness. Study A compared pre- versus post-dilution, and study B compared regional anticoagulation with heparin (pre-filter) and protamine (post-filter) (HP) versus nadroparin (NP) pre-filter. All CVVH sessions were standardised...

.... Aims: To discuss research performed at our institution which throws light on the causes of premature clotting of the hemofilter, and to highlight our approach to anticoagulation. Discussion: Premature clotting of the circuit is related to low baseline levels of antithrombin III (AT-III), heparin co...

...Mustafa Arıcı; Bülent Altun; Ozkan Dinler; Ahmet A. Kıykım; Celalettin Usalan; Yunus Erdem; Ünal Yasavul; Çetin Turgan; Sali Çağlar Background: There is increasing evidence for the role of nitric oxide (NO) in haemodialysis hypotension but the source of elevated NO is still controversial. Heparin...

... reflecting an effect of the extracorporeal circulation per se. In the present study the effect of heparin administration was investigated in 9 stable HD patients, and compared with that of saline. Blood samples were taken from the arteriovenous fistula before and 45 min after the administration of heparin...