...Clara Isabell Brozat; Michael Zoller; Sandra Frank; Mathias Bruegel; Caroline Gräfe; Diana Rebholz; Michael Paal; Helen Graf; Uwe Liebchen; Christina Scharf Introduction: Adsorption devices like CytoSorb ® (CS) are increasingly used in critically ill patients. However, potential adverse effects...

...-OH-midazolam were not removed during CVVHD and CVVHDF. However, 1-OH-midazolam-glucuronide was removed reasonably, approximately up to 43%. CRRT modality, filter integrity, and downtime affect this removal. These data imply a personalized titration of midazolam in critically ill patients with renal...

...Taniya Charoensareerat; Weerachai Chaijamorn; Pathakorn Kerdnimith; Nutsinee Kosumwisaisakul; Piyakamol Teeranaew; Dhakrit Rungkitwattanakul; Apinya Boonpeng; Nattachai Srisawat; Sutthiporn Pattharachayakul Introduction: The optimal meropenem dosing regimens in critically ill patients receiving...

... n a l d o s e * b o d y w e i g h t * S d / 60 Rapid identification and optimal treatment of bacterial infections are essential in intensive care unit (ICU) patients. Vancomycin is used in critically ill patients for the treatment of severe infections...

... the impact of HA 330 treatment on biochemical and hemodynamic parameters and cytokine levels in adult patients with septic shock. Methods: Critically ill patients with septic shock who received continuous veno-venous hemodiafiltration and HA 330 treatment were included in this prospective observational study...

... kidney injury in critically ill patients. However, a practical consensus for discontinuing CRRT is lacking. We aimed to develop a prediction model with simple clinical parameters for successful discontinuation of CRRT. Methods: Adult patients who received CRRT at Samsung Medical Center from 2007 to 2017...

... fluids Volume assessment Critically ill patients Fluid homeostasis in humans is tightly regulated under physiological conditions. Alterations of fluid volume and electrolyte balances can have multiple deleterious effects. In this review, we integrate old and new knowledge with in-depth...

...Eva Klijn; A.B. Johan Groeneveld; Michel E. van Genderen; Michiel Betjes; Jan Bakker; Jasper van Bommel Aim: Peripheral perfusion may predict harmful hypovolemic hypotension during fluid withdrawal by continuous veno-venous hemofiltration (CVVH) in critically ill patients with acute kidney injury...