In order to obtain performance data and biocompatibility characteristics of the two new Gambrane FD 100 polycarbonate hollow-fiber dialyzers (y-sterilized, dry or prefilled with isotonic saline) a paired in vivo evaluation was carried out. The measured data indicate that residual blood volume and small molecular weight clearances of Gambrane hollow-fiber dialyzers are not significantly different from comparable Cuprophan dialyzers. Small molecular clearance values are not affected by the significantly different ultrafiltration coefficients of the two tested FD 100 dialyzers. Biocompatibility of Gambrane as reflected by white blood cell count, platelet count and C3d is superior to Cuprophan.

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