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willebrand

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Book Chapter
Published: 20 June 2013
10.1159/000346923
EISBN: 978-3-318-02198-1
...References References 1. Bolton-Maggs PH, Lillicrap D, Goudemand J, Berntorp E: von Willebrand disease update: diagnostic and treatment dilemmas. Haemophilia 2008;14:(suppl 3)56-61 2. Lillicrap D: The basic science, diagnosis and clinical management of von Willebrand disease. Treatment...
Book Chapter
... Abstract Quantitative and qualitative defects of von Willebrand factor (VWF) cause von Willebrand disease (VWD),the most common inborn bleeding disorder being inherited in a mainly autosomal dominant but alsorecessive manner. According to its modular structure characterized by distinct...
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Book Chapter
Published: 20 June 2013
EISBN: 978-3-318-02198-1
...References References 1. Bolton-Maggs PH, Lillicrap D, Goudemand J, Berntorp E: von Willebrand disease update: diagnostic and treatment dilemmas. Haemophilia 2008;14:(suppl 3)56-61 2. Lillicrap D: The basic science, diagnosis and clinical management of von Willebrand disease. Treatment...
Book Chapter
Published: 20 June 2013
10.1159/000346914
EISBN: 978-3-318-02198-1
..., Rand ML, Tosetto A, Silva M, James PD: Evaluation of the diagnostic utility for von Willebrand disease of a pediatric bleeding questionnaire. J Thromb Haemost 2009;7:1418 6. Biss TT, Blanchette VS, Clark DS, Bowman M, Wakefield CD, Silva M, Lillicrap D, James PD, Rand ML: Quantitation of bleeding...
Book Chapter
Published: 20 June 2013
EISBN: 978-3-318-02198-1
..., Rand ML, Tosetto A, Silva M, James PD: Evaluation of the diagnostic utility for von Willebrand disease of a pediatric bleeding questionnaire. J Thromb Haemost 2009;7:1418 6. Biss TT, Blanchette VS, Clark DS, Bowman M, Wakefield CD, Silva M, Lillicrap D, James PD, Rand ML: Quantitation of bleeding...
Book Chapter
Series: Contributions to Nephrology
Volume: 169
Published: 14 January 2011
EISBN: 978-3-8055-9538-4
... 5. Tsai HM Lian EC: Antibodies to von Willebrand factor-cleaving protease in acute thrombotic thrombocytopenic purpura. N Engl J Med 1998; 339: 1585-1594 6. Galbusera M Noris M Remuzzi G: Inherited thrombotic thrombocytopenic purpura. Haematologica 2009; 94: 166-170 7. Thorpe CM...
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Book Chapter
Published: 09 February 1996
10.1159/000425375
EISBN: 978-3-318-04771-4
... that there is a third important inhibitor epitope within the light chain outside C2. Anti-A2 antibodies prevent normal function of the factor Xase complex of the intrinsic pathway of blood coagulation. Anti-C2 antibodies prevent the binding of fVIII to phospholipid and to von Willebrand factor, both of which...
Book Chapter
Series: Progress in Respiratory Research
Volume: 41
Published: 10 April 2012
10.1159/000335815
EISBN: 978-3-8055-9915-3
... of the targets for the currently available therapies [ 20 ], the concept of using ET levels as guidance to therapy has not been appropriately tested. D-Dimer and von Willebrand Factor The presence of prothrombotic mechanisms in the pathogenesis of PH has long been advocated. From endothelial dysfunction...
Book Chapter
Series: Contributions to Nephrology
Volume: 169
Published: 14 January 2011
10.1159/000314579
EISBN: 978-3-8055-9538-4
... (HUS). In TTP, systemic microvascular aggregation of platelets causes ischemia in the brain and other organs. In HUS, platelet-fibrin thrombi predominantly occlude the renal circulation. TTP can be inherited due to deficiencies in the activity of von Willebrand factor cleaving protease (ADAMTS13...
Book Chapter
Series: Endocrine Development
Volume: 22
Published: 30 July 2012
10.1159/000331697
EISBN: 978-3-8055-9337-3
..., and more than 50% of these young women have a coagulopathy such as thrombocytopenia, von Willebrand disease or leukemia [ 10 ]. Systemic bleeding disorders are found in 7-20% of women of all ages presenting with menorrhagia [ 11 ]. von Willebrand factor's deficiency is a common hereditary bleeding disorder...
Book Chapter
Series: Endocrine Development
Volume: 22
Published: 30 July 2012
EISBN: 978-3-8055-9337-3
... North Am 1981;28:369-378 11. Kouides PA: Obstetric and gynaecological aspects of von Willebrand disease. Best Pract Res Clin Haematol 2000;14:381-399 12. Kadir RA, Aledort LM: Obstetrical and gynaecological bleeding: a common presenting symptom. Clin Lab Haematol 2000;22:(suppl 1)12-16 13...
Book Chapter
Published: 20 June 2013
10.1159/000346922
EISBN: 978-3-318-02198-1
... with a platelet function disorder. J Thromb Haemost 2010;8:1416-1419 3. Bowman M, Riddel J, Rand ML, Tosetto A, Silva M, James PD: Evaluation of the diagnostic utility for von Willebrand disease of a pediatric bleeding questionnaire. J Thromb Haemost 2009;7:1418-1421 4. Konkle BA: Acquired disorders...