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Book Chapter
Book Chapter
Series: Translational Research in Biomedicine
Volume: 8
Published: 10 May 2022
10.1159/000522661
EISBN: 978-3-318-07054-5
... This monograph is humbly and fondly dedicated to those patients whose passing away and those experimental animals and cell lines whose sacrifice have made our task to understand brain stem death forthcoming. ...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 121
Published: 01 December 2020
10.1159/000507489
EISBN: 978-3-318-06698-2
... development. To emphasize the interrelations between economics and sustainable diets, the first two of the 17 Sustainable Development Goals (SDG) are: (1) No Poverty and (2) Zero Hunger. Every country has marginalized populations with food insecurity, aggravated by natural and man-made disasters and whose...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 42
Published: 06 December 2017
10.1159/000475680
EISBN: 978-3-318-06089-8
... Abstract The delusional misidentification syndromes (DMS) are a group of disorders, characterized by patients mistaking the identity of people they know, although they recognize them physically. The term DMS is an umbrella term which may cover disorders whose definition extends to objects other...
Book Chapter
Series: Monographs in Human Genetics
Volume: 16
Published: 17 April 2008
10.1159/000126561
EISBN: 978-3-8055-8521-7
... Abstract The NF1 gene encodes the giant protein neurofibromin (320 kDa), whose activity isimpaired in patients with neurofibromatosis type 1 (NF1). Understanding the biochemicalfunctions of neurofibromin is a key requirement for understanding NF1-associated diseasemechanisms at the molecular...
Book Chapter
Series: Contributions to Nephrology
Volume: 147
Published: 07 December 2004
10.1159/000082540
EISBN: 978-3-318-01169-2
... acid clearance through an inhibition of its renal tubularreabsorption (as probenecid), or through its metabolic conversion to a more solublecompound (as urate oxidase). Allopurinol is rapidly converted in the body to the activemetabolite oxypurinol whose total body exposure may be 20-fold greater than...
Book Chapter
Published: 10 July 1973
10.1159/000428679
EISBN: 978-3-318-04429-4
... concentration of propranolol. Eight patients formed a distinct group whose ratio of ß-blockade to plasma concentration was 2.6 times lower and whose ratio of plasma level to dosage was 2.5 times higher than those of the remaining 20 subjects. Since patients are dichotomous in their concentration-effect ratio...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 90
Published: 13 March 2019
10.1159/000490486
EISBN: 978-3-318-06341-7
... of infants to the establishment of normal gut colonization of the newborn in the prevention of the development of disease. She then provided vivid examples of that power illustrating that milk is more than just a nourishing biofluid, it is a metabolic system containing highly enriched metabolites whose...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 45
Published: 27 May 2021
10.1159/000514957
EISBN: 978-3-318-06844-3
..., and optogenetic mimicry of orexin cell activation rapidly causes locomotion. Neural ensemble calcium imaging experiments reveal that the same orexin cells whose activity underlies movement initiation display subsecond-latency responses to diverse sensory stimuli. These findings establish orexin neurons as rapid...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 55
Published: 31 October 2024
10.1159/000539936
EISBN: 978-3-318-07354-6
... presentation (related to the age of presentation, disease severity, concomitant hormone defects, and pre-existing comorbidities), the multi-organ involvement, and the variable outcome, whose determinants remain to be clarified. In the meanwhile, the evolution of radiological, histological, and molecular...
Book Chapter
Series: Frontiers in Diabetes
Volume: 29
Published: 31 August 2020
10.1159/000506560
EISBN: 978-3-318-06734-7
... Abstract The American Diabetes Association (ADA) was founded in 1940, and the European Association for the Study of Diabetes (EASD) was founded in 1965. In a little more than half a century, the EASD has evolved from a small association of academics into an effective medical society whose voice...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 44
Published: 20 May 2019
10.1159/000494952
EISBN: 978-3-318-06463-6
..., kanji-kana dissociation has been the central topic in Japanese aphasiology. Recent advancements in lesion-to-symptom analyses and functional imaging studies have identified some areas whose damage causes dissociative disturbances of reading or writing between kanji and kana. That is, (1) angular alexia...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 43
Published: 16 October 2018
10.1159/000490403
EISBN: 978-3-318-06394-3
... (1887-1961), are well-known. The cases of painters and sculptors who suffered from First World War neurological wounds are scarce. Nevertheless, their injuries led to intense modifications of artistic practice. We detail four examples of artists whose creative mind was impacted by their First World War...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 43
Published: 16 October 2018
10.1159/000490442
EISBN: 978-3-318-06394-3
... Abstract Raymond Roussel (1877-1933) was an eccentric writer whose strange novelistic and theatrical work was launched by the surrealists and is still worshipped by the French intelligentia. While writing his first text at the age of 19 years, he presented a delusional episode marked...
Book Chapter
Series: Current Problems in Dermatology
Volume: 54
Published: 21 August 2018
10.1159/000489518
EISBN: 978-3-318-06385-1
... of endogenous mechanisms - this is especially true for the skin whose pH is quite unique within the body. In this chapter, we summarize key endogenous factors and mechanisms that can influence the pH of the skin. Moreover, we highlight the significance of certain molecular systems (i.e., pH-sensing ionotropic...
Book Chapter
Series: Contributions to Nephrology
Volume: 196
Published: 09 August 2018
10.1159/000485715
EISBN: 978-3-318-06298-4
... like icodextrin to optimize volume control are important. PD patients whose BP is consistently >140/90 mm Hg should be treated to maintain SBP at <140 mm Hg and DBP at <90 mm Hg. There are no randomized studies examining different BP targets in relation to clinical outcomes in PD patients...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 89
Published: 06 August 2018
10.1159/000486501
EISBN: 978-3-318-06352-3
... given DHA-/ARA-supplemented formula, and similar results were shown for infants whose mothers were supplemented with DHA during pregnancy and breastfeeding. Long-term benefits of LC-PUFA supplementation in infancy have been reported in children aged 3-6 years. Follow-up studies of infants given DHA-/ARA...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 50
Published: 20 April 2018
10.1159/000486075
EISBN: 978-3-318-06339-4
.... While ergo- or chole-calciferol are rarely used alone as the sole source of vitamin D in hypoparathyroidism, these parental forms of vitamin D can be helpful, particularly in those whose 25(OH)D is low, as is common throughout the world. The availability of recombinant human PTH (1-84) as replacement...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 42
Published: 06 December 2017
10.1159/000475676
EISBN: 978-3-318-06089-8
... Abstract Ganser's syndrome is a rare and controversial condition, whose main and most striking feature is the production of approximate answers (or near misses) to very simple questions. For instance, asked how many legs a horse has, Ganser patients will reply “5”, and answers to plain...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 42
Published: 06 December 2017
10.1159/000475694
EISBN: 978-3-318-06089-8
... is that there is a linguistic trend, whose basic component is a stream of speech. This stream is suggested to use early-acquired rules of phonation, adapted according to socially meaningful values and attitudes, in an unconscious way. Therefore, the act of glossolalia is out of the “glossolalists” control. It would appear...