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Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
10.1159/000517657
EISBN: 978-3-318-06608-1
... is discussed. The EU Commission Recommendation of 2006 (2006/647/EC) [ 16 ] gave preference to methods without a health burden to human volunteers such as in vitro methods. Thus, besides the discussion of clinical in vivo methods like MED testing on protected and unprotected skin, also in vitro and in vivo...
Book Chapter
Series: Monographs in Oral Science
Volume: 29
Published: 12 January 2021
10.1159/000510194
EISBN: 978-3-318-06852-8
...% CHX, c , and 0.25% NYS solution, d ). Magnification ×2,000 ( a , c , d ); ×6,000 ( b ). Discussion This in vitro study investigated the activity of oral health care products (or their ingredients) on C. albicans and C. glabrata . Except for testing activity on planktonic yeast cells...
Book Chapter
Series: Monographs in Human Genetics
Volume: 21
Published: 11 September 2017
10.1159/000477285
EISBN: 978-3-318-06098-0
... Abstract The establishment of a robust and reliable culture system to study the differentiation of male germ cells in vitro has been a topic in developmental biology and reproductive medicine for over 100 years. Although successful approaches resulting in full mammalian spermatogenesis have...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 95
Published: 02 June 2010
10.1159/000315947
EISBN: 978-3-8055-9442-4
... Abstract The application and development of new in vitro techniques aims to enable a diagnosis to be reached while incurring no risk for the patient, a situation which is particularly desirable in the case of severe reactions like anaphylaxis. The in vitro diagnosis of anaphylaxis includes...
Book Chapter
Series: Developments in Ophthalmology
Volume: 45
Published: 11 May 2010
10.1159/000315023
EISBN: 978-3-8055-9419-6
... analysis of DES under particular environmental and treatment conditions a considerable lack of in vitro methods exists. The main disadvantage of current in vitro models is the limited experimental time frame of only several hours and the impossibility to evaluate healing of epithelial defects...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 66
Published: 26 May 2009
10.1159/000218209
EISBN: 978-3-8055-9036-5
... such as vector toxicity and load, viral serotype and backbone, and promoter specificity are discussed and contrasted for both in vivo vs. in vitro inner ear gene transfer. ...
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Book Chapter
Series: Endocrine Development
Volume: 12
Published: 24 September 2007
10.1159/000109604
EISBN: 978-3-8055-8386-2
... play an essentialrole in the proliferation of precursor cells. In the present review, we focused on the roles of fibroblastgrowth factors (FGFs) in pancreas development. Improvements of the in vivo and in vitro techniqueswere used to define the function of FGF10. Experiments on FGF10 knockout mice...
Book Chapter
Published: 31 May 2007
10.1159/000104215
EISBN: 978-3-318-01454-9
... Abstract In clinical practice, side effects of drugs are a major problem.A broad range of drugs can elicit many different immunemediateddiseases with distinct pathomechanisms. In thischapter, we focus on current in vitro techniques for the diagnosisof T-cell-mediated drug hypersensitivity...
Book Chapter
Published: 31 May 2007
10.1159/000104216
EISBN: 978-3-318-01454-9
... allergens and their concentration, can affectthe results of the BATs. The BAT is more sensitive and specificthan other in vitro diagnostic techniques in drug allergy.In various studies, its sensitivity in allergy to musclerelaxantdrugs ranges between 36 and 97.7%, with aspecificity of around 95...
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Series: Chemical Immunology and Allergy
Volume: 88
Published: 11 August 2005
10.1159/000087822
EISBN: 978-3-318-01233-0
... fluids may affect fertilization and early embryonic development. In humans, it hasbeen shown that follicular fluid exerts chemotactic activity towards neutrophilic granulocytesand that the concentrations of this activity are related to the outcome of in vitro fertilization(IVF) treatment. The present...
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Series: Monographs in Oral Science
Volume: 18
Published: 22 October 2001
10.1159/000061647
EISBN: 978-3-318-00704-6
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