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Series: Nestlé Nutrition Institute Workshop Series
Volume: 94
Published: 09 June 2020
10.1159/000505338
EISBN: 978-3-318-06685-2
... source of potential competitors of viral glycan receptors, which mimic the structures of blood group-active O-glycans. For example, the trisaccharide 2′-fucosyllactose (2′FL) is able to block norovirus binding quite efficiently [ 9 , 10 ], and it has reached market approval as a save food additive...
Book Chapter
Series: Fast Facts Collection 2006-2015
Published: 03 November 2014
10.1159/000491234
EISBN: 978-1-908541-83-3
Book Chapter
Series: Current Problems in Dermatology
Volume: 45
Published: 13 March 2014
10.1159/000355961
EISBN: 978-3-318-02527-9
..., other anogenital cancers, oropharyngeal cancers, and cutaneous malignancies in susceptible individuals, causing an estimated 5.2% of virally associated cancers worldwide. HPVs are small, double-stranded DNA viruses of the Papillomaviridae family; to date 150 genotypes have been characterized...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 16
Published: 07 May 2012
10.1159/000332122
EISBN: 978-3-8055-9830-9
..., while patients infected as adults have a risk of 2–10%. The treatment of chronic hepatitis B should be assessed case by case, depending on viral load, biochemical parameters and inflammation within the liver. Infections due to hepatitis C virus occur most often without symptoms and most patients...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 16
Published: 07 May 2012
10.1159/000332130
EISBN: 978-3-8055-9830-9
... Abstract Non-viral pathogens affecting liver leading on to parenchymal or biliary damage is uncommon, however mild to moderate hepatic dysfunction is not uncommon in bacteremic patients. The etiology of non-viral infection of the liver varies with geographical location as parasitic infestations...
Book Chapter
Series: Progress in Respiratory Research
Volume: 41
Published: 10 April 2012
10.1159/000334362
EISBN: 978-3-8055-9915-3
... lesions of patients with PAH-HIV [ 19 ]. However, viral proteins and their interactions with molecular partners in the infected host may promote apoptosis, growth, and proliferation. Excessive production of endothelin-1 (ET-1) has been implicated in endothelial cell dysfunction and in the pathogenesis...
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
10.1159/000323306
EISBN: 978-3-8055-9687-9
... Abstract Much attention has been focused on the elucidation of mechanisms whereby atopic dermatitis (AD) skin lesions are especially susceptible to certain viral infections, such as herpes simplex virus (HSV). Although one of the most likely hypotheses is that the primary defect...
Book
Book Cover Image
Series: Developments in Biologicals
Volume: 133
Published: 22 March 2011
Book Chapter
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 66
Published: 26 May 2009
10.1159/000218209
EISBN: 978-3-8055-9036-5
... Abstract The lack of effective treatments for many forms of hearing and vestibular disorders has produced interest in virally mediated gene therapies. However, to develop a gene therapy strategy that would successfully treat inner ear disorders, appropriate viral vectors capable of transfecting...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317143
EISBN: 978-3-8055-9596-4
... Abstract Many factors play into the complexity of viral pathogenesis. Understanding viral pathogenesis is key to developing vaccines and treatments for viral diseases. One emerging area of research is proteomics, which is the study of the protein complement and functions of the genome. Many...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317148
EISBN: 978-3-8055-9596-4
... Abstract Bovine viral diarrhoea viruses (BVDV) are significant pathogens of cattle worldwide. These viruses exist in both non-cytopathic and cytopathic biotypes. Non-cytopathic BVDV can establish persistent lifelong infections in cattle and are a frequent contaminant of biological reagents...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317188
EISBN: 978-3-8055-9596-4
... this possibility, we have generated transgenic mice that express RNAi molecules targeting a conserved region of the influenza A NP gene and are testing these mice for resistance to influenza infection. Transgenes were initially developed that express short hairpin RNAs (shRNAs) targeting multiple influenza A viral...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 1
Published: 01 July 2008
10.1159/000141038
EISBN: 978-3-8055-8577-4
... will discuss the pathogenesisof Kaposi sarcoma and KSHV-induced lymphoma, including primary effusion lymphoma and multicentricCastleman disease. We will also provide a brief introduction to the virus itself. We particularly focus onthe viral gene expression pattern together with the current animal models...