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vca

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Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444967
EISBN: 978-3-318-05867-3
... Abstract Vascularized composite allotransplantation (VCA) can achieve close to optimal aesthetic restoration of devastating tissue defects not amenable to conventional reconstruction, with improved functional outcomes and avoidance of multiple surgeries or donor site morbidity. During the past...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444970
EISBN: 978-3-318-05867-3
... Abstract Vascularized composite allotransplantation (VCA) has demonstrated promising results and potential, expanding possibilities for defects not amenable to reconstruction by means of autologous tissue transplantation. Success in VCA relies on multidisciplinary efforts derived from different...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444966
EISBN: 978-3-318-05867-3
... Abstract Vascularized composite allotransplantation (VCA) is the youngest field in organ transplantation. While not necessarily life-saving per se, VCA was introduced with the intention to treat complex and otherwise untreatable tissue injuries and defects of complex body elements...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444973
EISBN: 978-3-318-05867-3
... Abstract Although vascularized composite allotransplantation (VCA) of the face and extremities has been successfully performed with satisfactory aesthetic and functional outcomes, potentially serious side effects derived from long-term immunosuppression impede broader application of VCA...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444971
EISBN: 978-3-318-05867-3
... Abstract Vascularized composite allotransplantation (VCA) poses different challenges to solid organ transplantation because of the immunogenicity difference of different tissues in a single composite allograft, as well as the difficulties in functional assessment of the allograft. The majority...
Book
Book Cover Image
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/isbn.978-3-318-05867-3
EISBN: 978-3-318-05867-3
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444972
EISBN: 978-3-318-05867-3
... Abstract Vascularized composite allotransplantation (VCA) has emerged as a viable means of restoring forms and functions in patients with significant tissue defects. However, administration of lifelong immunosuppression in VCA is complicated with side effects and reduces immunocompetence...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444975
EISBN: 978-3-318-05867-3
.... Their characteristics prompted their evaluation as candidate molecular markers and therapeutic agents to monitor or treat patients with vascularized composite allotransplantation (VCA): their specific circulating expression profile that could serve as noninvasive predictive tools or surrogate end points for rejection...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444965
EISBN: 978-3-318-05867-3
... (VCA) is the only form of reconstruction that truly upholds Gillies' principle of replacing like with like (fig. 4 ). It is said that the saints Damian and Cosmas performed the first extremity transplant in a cancerous man 348 years after the death of Christ, though there is room for skepticism...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444976
EISBN: 978-3-318-05867-3
... they can be generated from the patient's own somatic cells through various reprogramming techniques, iPSCs have great potential in disease modeling, drug screening, regenerative medicine, and cell therapy. Vascularized composite allotransplantation (VCA) differs from organ transplantation involving...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444974
EISBN: 978-3-318-05867-3
... with tissomic studies, the histological study of an en bloc animal. Bioimaging has established its application in all of the three major domains of vascularized composite allotransplantation (VCA) research, including rejection and tolerance, structural and functional recoveries, and therapeutic assessments...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444969
EISBN: 978-3-318-05867-3
... = 10), followed by the United States (n = 9), Turkey (n = 5), Spain (n = 3), Poland (n = 2), Belgium, and China (n = 1) [ 6 ]. Despite encouraging and ongoing advancements in the field of vascularized composite allotransplantation (VCA), the potential consequences of lifelong immunosuppression...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 5
Published: 04 July 2016
10.1159/000444968
EISBN: 978-3-318-05867-3
.... Vascularized composite allotransplantation (VCA) or reconstructive transplantation is an emerging new era in transplant medicine and has become a viable reconstructive option for patients with large and devastating tissue defects. Advances in microsurgical techniques and transplant immunology...
Book
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Series: Progress in Tumor Research
Volume: 21
Published: 14 March 1978
10.1159/isbn.978-3-318-04174-3
EISBN: 978-3-318-04174-3
Book
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Series: Advances in Oto-Rhino-Laryngology
Volume: 60
Published: 17 May 2002
10.1159/isbn.978-3-318-00764-0
EISBN: 978-3-318-00764-0
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Series: Antibiotics and Chemotherapy
Volume: 29
Published: 05 August 1981
10.1159/isbn.978-3-318-03204-8
EISBN: 978-3-318-03204-8
Book
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Series: Antibiotics and Chemotherapy
Volume: 38
Published: 08 July 1987
10.1159/isbn.978-3-318-03213-0
EISBN: 978-3-318-03213-0
Book
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Published: 28 February 1990
10.1159/isbn.978-3-318-04949-7
EISBN: 978-3-318-04949-7
Book
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Series: Current Studies in Hematology and Blood Transfusion
Volume: 43
Published: 31 May 1976
10.1159/isbn.978-3-318-03513-1
EISBN: 978-3-318-03513-1
Book
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Series: Contributions to Nephrology
Volume: 161
Published: 30 May 2008
10.1159/isbn.978-3-8055-8567-5
EISBN: 978-3-8055-8567-5