... specific properties and their functioning is regulated by variousmechanisms. In this chapter we compare the physiological differences between these channelsand discuss the factors involved in modulation of channel properties. Next, we evaluatehow alterations in expression and differential regulation...

... Abstract Gene and RNA interference therapies are promising cures for intractable renal failure.However, low delivery efficiency of the therapeutic nucleic acid into the nucleus of the targetcell is a significant obstacle in the clinical application of nonviral gene therapy. Variousmechanical...