... Abstract Ultrafiltration in peritoneal dialysis occurs through endothelial water channels (free water transport) and together with solutes across small pores: solute coupled water transport. A review is given of cross-sectional studies and on the results of longitudinal follow-up. ...

...References References 1. Cnossen TT, Smit W, Konings CJAM, Kooman JP, Leunissen KM, Krediet RT: Quantification of free water transport during the peritoneal equilibration test. Perit Dial Int 2009;29:523-527. 2. La Milia V, Limardo M, Virga G, Crepaldi M, Locatelli F: Simultaneous...

..., we will provide a detailed quantitative analysis of the transport processes involved in different hemodialysis (HD) therapies. We will also report some technical aspects of hollow fiber membranes and filters composed of them along with the mechanisms of solute and water removal for such devices...

... Abstract In the last few years, many studies have pinpointed the crucial role of thyroid hormone (TH) transporters for TH action in human target cells. The importance was better documented by the phenotype observed in patients harboring mutations of the monocarboxylate transporter 8 (MCT8...

... Abstract Ultrafiltration failure is one of the main concerns for patients on long-term peritoneal dialysis. According to the three-pore model of peritoneal transport, peritoneal water flows via four pathways: ultrasmall pores, small pores, large pores and through peritoneal or lymphatic...

... Abstract Human essential hypertension and rodent genetic hypertension are associated with increased sodium transport in the renal proximal tubule and medullary thick ascending limb of Henle. The proximal tubule, which secretes endothelin (ET), expresses the ET B receptor. Low (nM...

... involved. Role of Endothelin-1 in Thick Ascending Limb Sodium Chloride Transport Zeidel et al. [ 1 ] first reported that endothelin (ET)-1 inhibited tubular transport in inner medullary collecting duct cells. Direct actions on nephron transport were later supported by in vivo data showing...

... (Na) and water excretion. This review will describe the role of ET-1 in the physiologic regulation of renal Na water transport and discuss the mechanisms by which such regulation occurs. As will become apparent, the CD ET system provides a vital link between extracellular fluid volume (ECFV) and renal...

... Abstract The rate of transport of small solutes across the peritoneal membrane is one of the most important measurements in PD patients. Signifi cant between-patient variability is associated with an impact on small solute clearance, ultrafi ltration and even survival. Cross-sectional...

... Abstract The transport characteristics of the peritoneal membrane will differ between patients, and will change over time in individual patients, which in turn will affect the fluid and solute transport kinetics of peritoneal dialysis (PD) as well as the dialysis efficiency. There are several...

... and theaction of chemoattractants, hormones and transmitters, which frequently alter the electricalproperties of a cell and thus cause cell swelling or shrinkage, respectively. On the otherhand, a migrating cell actively has to govern cell volume regulatory ion transport mechanismsin order to create...

... transcapillary ultrafiltration by a mechanism resembling ‘colloid’ osmosis (with theultrafiltration occurring mainly through the small pores) almost no sieving of solutes isobserved with icodextrin-based solution resulting in increased convective transport andclearance of small solutes. In general, the transport...

... Abstract The cystic fibrosis transmembrane conductance regulator(CFTR) is a unique member of the ATP-binding cassette(ABC) transporter superfamily that plays a critical role in fluidand electrolyte transport across epithelial tissues. CFTR iscomposed of two membrane-spanning domain (MSD...