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translational

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Book Chapter
Book Chapter
Series: Frontiers in Diabetes
Volume: 25
Published: 19 April 2017
10.1159/000454695
EISBN: 978-3-318-06025-6
... reprogramming technologies are providing new opportunities and challenges for in vitro human cell-based diabetes modelling and for novel drugs and cell-based diabetes therapy discovery.This review chapter focuses on the lessons learned from MODY gene identification to clinical translational research...
Book
Book Cover Image
Series: Frontiers of Neurology and Neuroscience
Volume: 36
Published: 16 December 2014
10.1159/isbn.978-3-318-02791-4
EISBN: 978-3-318-02791-4
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 29
Published: 23 September 2013
10.1159/000353618
EISBN: 978-3-318-02464-7
... the most effective treatment for a patient in a timely and cost-effective way. Translational research that investigates endophenotype predictors of treatment response in OCD and related disorders may pave the way toward personalised medicine. Such research is likely to require multidisciplinary...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 32
Published: 03 July 2013
10.1159/000346414
EISBN: 978-3-318-02309-1
..., a variety of questions or problems still remain to be solved [ 4 , 5 ]. In this review, we present recent progress in basic and translational research on the field of BMSC transplantation for ischemic stroke, and critically discuss what should be clarified to establish BMSC transplantation therapy...
Book Chapter
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343146
EISBN: 978-3-318-02285-8
... Abstract During the past six years, multiple countries have embraced the concept of translational medicine. This is generally understood as improving prevention and treatment strategies for patients and for communities through translating discoveries in basic and clinical research into products...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343010
EISBN: 978-3-318-02285-8
... Abstract The US Clinical and Translational Science Awards (CTSAs) have had a transformative impact on clinical and translational research and research education and training. As a member of the first cohort of funded CTSAs in 2006, the University of California Davis Clinical and Translational...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343024
EISBN: 978-3-318-02285-8
... for the development of new approaches based on scientific discoveries emerging from medical research. The application of translational research has enormous potential for addressing these challenging clinical needs. Fundamental research applied to drug discovery and delivery, biomarkers for medical decision-making...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343028
EISBN: 978-3-318-02285-8
... Abstract The training of a workforce with translational research skills has been an essential part of the Clinical and Translational Science Award Program of the NIH since 2006. This training has emphasized broad multidisciplinary skills to address translational research problems but also...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343019
EISBN: 978-3-318-02285-8
... and translational research based upon the core training components of the National Institutes of Health (NIH) and the NIH founded CTSA institutions. The initial outcomes of training clinical and translational researchers in China were not only advanced the concepts, but also the expertises were able to be adapted...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343027
EISBN: 978-3-318-02285-8
... Abstract A new model for translational medicine has been created at the Center for Translational Research in Biomedical Sciences (CTRBS) at Kaohsiung Chang Gung Memorial Hospital in the southern city of Kaohsiung in Taiwan. This chapter describes how the core value of a private enterprise...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343022
EISBN: 978-3-318-02285-8
... Abstract Translational research in medicine is facing burdens stemming from an increase in the complexity of science, increase in partnerships across national and international collaborations, and reduction in the finite resources to support all research endeavors. Schools of business offer...
Book Chapter
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/000343025
EISBN: 978-3-318-02285-8
... Abstract Evaluators face challenges such as program and intervention variability, time and budgetary constraints, and a complicated range of internal and external stakeholders. The design and implementation of evaluation for translational research (TR) is especially challenging since...
Book Chapter
Book
Book Cover Image
Series: Translational Research in Biomedicine
Volume: 3
Published: 21 December 2012
10.1159/isbn.978-3-318-02285-8
EISBN: 978-3-318-02285-8
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 30
Published: 22 June 2012
10.1159/000338367
EISBN: 978-3-318-02184-4
... Abstract The so-called translational research can be defined as ‘the process of applying ideas, insights and discoveries generated through basic scientific inquiry to the treatment or prevention of human disease’. It also accommodates ‘taking ideas from clinical practice and research back...
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