... Abstract Trabeculectomy with antifibrotic treatment is still the most popular incisional procedure for glaucoma filtration surgery (GFS) worldwide. The advent of antifibrotic agents reduced failure due to scarring but resulted in increased complications. Advances in trabeculectomy surgery have...

... Abstract Trabeculectomy with anti-fibrotic treatment is still the most popular incisional procedure for glaucoma filtration surgery (GFS) worldwide. The advent of anti-fibrotic agents reduced failure due to scarring but resulted in increased complications. Advances in trabeculectomy surgery...

...References References 1. Cairns JE: Trabeculectomy: preliminary report of a new method. Am J Ophthalmol 1968;66:673-679. 2. Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL: Treatment outcomes in the Tube versus Trabeculectomy study after one year of follow-up. Am J...

... use in trabeculectomy surgery. J Glaucoma 2008;17:423-430. 5. Loon SC, Chew PT: A major review of antimetabolites in glaucoma therapy. Ophthalmologica 1999;213:234-245. 6. Francis BA, Du LT, Najafi K, Murthy R, Kurumety U, Rao N, Minckler DS: Histopathologic features of conjunctival filtering...

... culture, MMC induces apoptosis, which explains its long-lasting antiproliferative effect even after a single administration in trabeculectomy [ 5 ]. As a consequence, several filtering blebs that developed after a single intraoperative application of MMC showed diffusely enhanced filtration, microcysts...

...References References 1. Cairns JE: Trabeculectomy. Preliminary report of a new method. Am J Ophthalmol 1968;66:673-679 2. Gedde SJ, Schiffman JC, Feuer WJ, Herndon LW, Brandt JD, Budenz DL: Treatment outcomes in the Tube Versus Trabeculectomy Study after one year of follow-up. Am J...

... in trabeculectomy surgery. J Glaucoma 2008;17:423-430 5. Loon SC, Chew PT: A major review of antimetabolites in glaucoma therapy. Ophthalmologica 1999;213:234-245 6. Francis BA, Du LT, Najafi K, Murthy R, Kurumety U, Rao N, Minckler DS: Histopathologic features of conjunctival filtering blebs. Arch...

... explains its long-lasting antiproliferative effect even after a single administration in trabeculectomy [ 5 ]. As a consequence, several filtering blebs developed after a single intraoperative application of MMC showed diffusely enhanced filtration, microcysts, and hypocellularity, avascularity, decreased...

..., Jayagandan A: Surgical results of combined trabeculotomy-trabeculectomy for developmental glaucoma. Ophthalmology 1998;105:974-982. 25. Campos-Mollo E, Moral-Cazalla R, Belmonth-Martinez J: Combined trabeculotomy-trabeculectomy as the initial surgical procedure of primary developmental glaucoma...

...References References 1. Papadopoulos M, Khaw PT: Improving glaucoma filtering surgery. Eye (London) 2001;15:131-132. 2. Wells AP, Bunce C, Khaw PT: Flap and suture manipulation after trabeculectomy with adjustable sutures: titration of flow and intraocular pressure in guarded filtration...

..., Steinmann WC: The effects of postoperative corticosteroids on trabeculectomy and the clinical course of glaucoma: five-year follow-up study. Ophthalmic Surg 1991;22:724-729. 3. Seibold LK, Sherwood MB, Kahook MY: Wound modulation after filtration surgery. Surv Ophthalmol 2012;57:530-550. 4. Van...

... complications and failures, remain the gold standard of glaucoma surgery. However, trabeculectomy is a surgery in which we create a hole in the eye and hope that this hole will heal, albeit not too much. It is therefore not surprising that it may be affected by complications and failures. Obviously, many...

... to the art of the glaucomologist seeking continually better surgical treatments for the debilitating disease of glaucoma. A major component of guarded filtration surgery since its inception in 1968 has been the trabeculectomy. This surgery involves the creation of a scleral flap with an underlying opening...

... extraction by PE results in a moderate decrease in both IOP (-20%) and the number of drugs required after surgery (-35%) [ 1 ]. IOP spikes after PE have been observed more frequently in exfoliative glaucoma than in primary open-angle glaucoma [ 8 ]. Phacoemulsification following Trabeculectomy in Patients...

...References References 1. Castelli A: Tecnica di ‘fistolizzante profonda' antiglaucomatosa (fistolizzazione sotto lembo sclerocorneale, con iridectomia periferica o totale, con, o senza, iridenclesis a grembiule). Atti Soc Oftalmol Lombarda 1965;1:21-28. 2. Cairns JE: Trabeculectomy...

...-surgeon series. J Cataract Refract Surg 2008;34:1834-1841. 9. AGIS (Advanced Glaucoma Intervention Study) Investigators: The Advanced Glaucoma Intervention Study: 8. Risk of cataract formation after trabeculectomy. Arch Ophthalmol 2001;119:1771-1779. 10. Klink J, Schmitz B, Lieb WE, et al...

... are the preferred initial treatments for primary congenital glaucoma. Trabeculectomy with adjunctive mitomycin C is more likely to succeed in older, phakic patients, but carries the long-term risk of bleb-associated endophthalmitis. Glaucoma drainage devices may be preferred in younger children and in patients...