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tfh

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Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441902
EISBN: 978-3-318-05651-8
..., Alox5 −/− mice were unable to fully foster the development of T follicular helper (Tfh) cells, even after immunization with foreign antigens of sheep red blood cells [ 8 ]. Our results illustrated the novel role of Alox5 in adaptive humoral immunity by managing primary B cells and Tfh cells. However...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441878
EISBN: 978-3-318-05651-8
... emerging studies have implicated follicular helper T (Tfh) cells as critical regulators of antigen-specific humoral immunity [ 3 ] because they secrete IL-4 and help B cells to produce immunoglobulin E (IgE) [ 4 ]. Regulatory B (Breg) cells, which regulate immune responses mediated by other immune cells...
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Book
Book Cover Image
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published online: 28 April 2016
Published in print: 29 April 2016
10.1159/isbn.978-3-318-05651-8
EISBN: 978-3-318-05651-8
Book Chapter
Series: Current Directions in Autoimmunity
Volume: 11
Published: 18 February 2010
10.1159/000289195
EISBN: 978-3-8055-9384-7
... and the production of arthritogenic antibodies is drastically reduced [ 165 ]. We also found that the differentiation of arthritogenic CD4 T cells to a Tfh phenotype and their CXCR5-dependent migration into B cell follicles are critical steps for autoreactive GC formation, autoantibody production and disease...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 100
Published: 27 May 2014
10.1159/000358622
EISBN: 978-3-318-02195-0
... mainly occur within germinal centers, and the CD4+ T cells that enter the germinal centers to mediate their helper function for antibody production have been termed T follicular helper (Tfh) cells [ 10 ]. The possibility that Tfh cells represent an independent lineage, essentially parallel to Th1, Th2...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 43
Published: 04 May 2020
10.1159/000504479
EISBN: 978-3-318-06678-4
... to the light zone as centrocytes where rescue signals are provided by follicular dendritic cells (FDC) and T follicular helper (Tfh) cells. Since germinal centre centrocytes do not have the anti-apoptotic protein Bcl2, they will die by apoptosis unless they receive rescue signals which are conditional...
Book Chapter
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 43
Published: 04 May 2020
10.1159/000504487
EISBN: 978-3-318-06678-4
... antigen re-exposure. By upregulating the expression of eomesodermin, cytotoxic memory CD4 T cells are also capable of directly lysing viral infected cells. CD4 T cells, particularly T follicular helper cells (Tfh), are recognised for their essential roles in supporting the formation of germinal centres, B...
Book
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Series: Fast Facts Collection 2016
Published: 18 August 2016
10.1159/isbn.978-1-910797-28-0
EISBN: 978-1-910797-28-0
Book
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Published: 16 October 2018
10.1159/isbn.978-1-910797-95-2
EISBN: 978-1-910797-95-2
Book
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Published: 25 April 2019
10.1159/isbn.978-1-912776-31-3
EISBN: 978-1-912776-31-3
Book
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Series: Current Directions in Autoimmunity
Volume: 11
Published: 18 February 2010
10.1159/isbn.978-3-8055-9384-7
EISBN: 978-3-8055-9384-7
Book
Book Cover Image
Series: Interdisciplinary Topics in Gerontology and Geriatrics
Volume: 43
Published online: 09 April 2020
Published in print: 04 May 2020
10.1159/isbn.978-3-318-06678-4
EISBN: 978-3-318-06678-4
Book
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Series: Advances in Oto-Rhino-Laryngology
Volume: 72
Published: 10 August 2011
10.1159/isbn.978-3-8055-9723-4
EISBN: 978-3-8055-9723-4
Book
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Series: Advances in Oto-Rhino-Laryngology
Volume: 79
Published online: 28 July 2016
Published in print: 03 August 2016
10.1159/isbn.978-3-318-05854-3
EISBN: 978-3-318-05854-3
Book
Book
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Series: Chemical Immunology and Allergy
Volume: 100
Published: 27 May 2014
10.1159/isbn.978-3-318-02195-0
EISBN: 978-3-318-02195-0
Book
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Series: Monographs in Human Genetics
Volume: 11
Published: 04 April 1986
10.1159/isbn.978-3-318-04003-6
EISBN: 978-3-318-04003-6
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Published: 31 December 1918
10.1159/isbn.978-3-318-04592-5
EISBN: 978-3-318-04592-5
Book
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Published: 29 August 1980
10.1159/isbn.978-3-318-05074-5
EISBN: 978-3-318-05074-5