Search Results for structure

... Abstract The spectrum of bone morbidity in childhood cancer survivors (CCS) is broad and extends beyond “low bone mineral density” to structural damage including fracture-induced vertebral deformity, and joint collapse due to osteonecrosis or slipped capital femoral epiphysis. In addition...

... Abstract We here summarize the structures of the laryngeal vocal fold as well as its insertion structures at the anterior commissure and at the area of the vocal process and place these findings within the context of biomechanical, functional, and clinical implications. The paired...

... Abstract Oligosaccharides are a group of complex glycans that are present in the milk of most mammals. However, human milk is unique as the concentrations of human milk oligosaccharides (HMOs) are much higher than those of other mammals, and their structural composition is more complex...

... between the cortex and the medulla. It is mainly composed of small T lymphocytes representing the zone of T cell competence (Fig. 1 a). The medulla is the area below the cortex/paracortex where the lymph is conveyed towards the hilus and the efferent lymphatic ducts. The medulla is mainly structured...

... that the germ line function of the AZF loci in Yq11 may be not only based on the expression of some germ cell proteins, but also on the expression of some germ cell-specific TTTY transcripts and a locally dynamic and specific chromatin folding structure probably controlled by some germ cell-specific nuclear...

... the List has evolved, the processes that make this possible, and look at what new drugs and methods may find their way into future Lists. Legal Context - The Code The structure and contents of the List are defined in the 2003, 2009, and 2015 World Anti-Doping Codes (the Code). The Code...

..., and surface force techniques. Additionally, it highlights recent developments in the use of biocompatible polymeric biomaterials for dialyzers and provides an overview of the progress made in the design of multifunctional biomedical polymers by controlling the biointerfacial water structure through precision...

... the best (and at present the only) model to assess the efficacy, tolerability, and safety of any treatment for all clinical conditions, including neurological disorders. The structure of the trial is based on the need to disentangle the effects of an experimental treatment (to be compared to one or more...

..., these molecular alterations lead to structural modifications of the hair fiber, decrease in melanin production, and lengthening of the telogen phase of the hair cycle. Despite this inevitable progression with aging, there exists an array of treatments such as light therapy, minoxidil, and finasteride which have...

... Abstract The hippocampus is a temporal brain structure belonging to the limbic lobe and is fundamentally involved in memory processing, learning, and emotions. It consists of two allocortex laminae: the gyrus dentatus and the cornu ammonis, one rolled up inside the other, creating a bulge...

... structure that implies dependence on the host for much metabolic capability. Certain groups of genes, including those encoding inclusion membrane proteins and the family of Pmp proteins, have been significantly expanded against this general reductive evolutionary strategy. Pregenomic and postgenomic...

... Abstract This chapter reviews the structure and allosteric regulation of glutamate dehydrogenase (GDH). For decades, it was known that mammalian GDH was regulated by a wide array of metabolites, but the reason for such regulation was not at all clear. The demonstration that hyperinsulinism...

... Abstract Periodontitis is an inflammatory disease of the oral cavity initiated by a microbial biofilm (or ‘dental plaque’). Subgingival biofilms in periodontal pockets are not easily analyzed without the loss of structural integrity. These subgingival plaques are structured communities...

... Abstract Purpose: The structure of the lid margin is insufficiently understood and defined, although it is of obvious importance in ocular surface integrity. Methods: The structure and function of the different zones of the lid margin are explained with a focus on dry eye disease. Results...

... as to the impact of nutrients on regulation of gene expression and disease susceptibility. For example, the classic view of cancer etiology is that genetic alterations (via genotoxic agents) damage DNA structure and induce mutations resulting in non-functional proteins that lead to disease progression. Aberrant...

... for saliva that are described in detail by Tucker [pp.21-31]. Structures and Cell Types of Adult Salivary Glands Mature adult salivary glands consist of a parenchyma, the glandular secretory tissue, and a stroma, which is the supporting connective tissue. The parenchyma is composed of secretory units...

... and enamel formation [ 3‒6 ]. While amelogenins are not the only proteins in the developing enamel matrix, they have nevertheless been attributed a major role in the growth of elongated enamel crystals [ 3‒6 ]. In previous studies from our laboratory, we have characterized the structure of the amelogeninrich...