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steroid

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Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 195
Published: 22 May 2018
10.1159/000486930
EISBN: 978-3-318-06350-9
... Abstract Minimal change nephrotic syndrome (MCNS) usually responds to steroids but frequently relapses, requiring additional treatment with immunosuppressive agents. Rituximab is a chimeric murine/human monoclonal immunoglobulin G1 antibody that targets CD20, a B-cell differentiation marker. B...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438891
EISBN: 978-3-318-02789-1
... hypogonadotropic hypogonadism and hypergonadotropic hypogonadism. Treatment of isolated CDGP involves expectant observation or short courses of low-dose sex steroid supplementation. More complex and involved management is required in males with hypogonadism to achieve both development of secondary sexual...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438892
EISBN: 978-3-318-02789-1
... in estrone (E 1 ) [ 3 ] and androgens [ 6 ]. Most endogen anabolic steroid hormones found in the circulation have a circadian pattern during puberty in both sexes with low levels around midnight and high in the morning [ 5 , 6 , 7 , 8 ]. This circadian rhythm becomes less pronounced at the time of menarche...
Book Chapter
Series: Endocrine Development
Volume: 27
Published: 15 September 2014
10.1159/000363612
EISBN: 978-3-318-02559-0
... Abstract Accurate analysis of steroid hormones represents an essential part in the evaluation of a patient with disorders or differences in sex development. Analytical methods based on mass spectrometry (MS) have become the state-of-the-art methodology allowing for the most specific qualitative...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 72
Published: 10 August 2011
10.1159/000324592
EISBN: 978-3-8055-9723-4
... Abstract IgA nephropathy (IgAN), the most common form of primary glomerulonephritis progressing to end-stage renal disease (ESRD), has been regarded as an incurable disease. However, in recent years, it has been demonstrated that combined tonsillectomy with steroid pulse (TS) therapy...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 72
Published: 10 August 2011
10.1159/000324606
EISBN: 978-3-8055-9723-4
... Abstract Tonsillectomy combined with steroid pulse therapy has been a popular approach to treating IgA nephropathy (IgAN) in Japan for several years. However, little is understood about how such combined therapy affects the clinical course of IgAN. We therefore compared the effects...
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/000125925
EISBN: 978-3-8055-8545-3
... Abstract Long-term outcomes for patients with nephrotic syndrome (NS) correlate closely withthe degree of steroid responsiveness. There are currently no diagnostic tests that accuratelypredict steroid responsiveness in NS. In children in particular, a prolonged course of daily,high-dose...
Book Chapter
Series: Contributions to Nephrology
Volume: 157
Published: 25 May 2007
10.1159/000102310
EISBN: 978-3-318-01467-9
... stage 4. The number of subjects with steroid monotherapy were 1 (stage 1), 7(stage 2), 9 (stage 3) and 1 (stage 4). The primary endpoint in this study was normalized urinalysisas clinical remission. The remission rate treated with combined therapy was 86.2% instage 1, 73.1% in stage 2, and 43.8...
Book Chapter
Series: Endocrine Development
Volume: 8
Published: 15 February 2005
10.1159/000084100
EISBN: 978-3-318-01178-4
... clinical cases hasshown that many of the growth-promoting effects of the sex steroids are mediated throughestrogens rather than androgens. In addition, skeletal maturation and epiphyseal fusion arealso estrogen-dependent in both sexes. Nevertheless, independent actions of androgens inthese processes also...
Book Chapter
Series: Contributions to Nephrology
Volume: 146
Published: 28 October 2004
10.1159/000082059
EISBN: 978-3-318-01168-5
... Abstract Steroids have accompanied other immunosuppressants throughout the history of renaltransplantation. However, its permanent use has been associated with a myriad of adverseeffects, which especially increase the already high cardiovascular risk of renal transplantpatients. Nevertheless...
Book Chapter
Series: Contributions to Nephrology
Volume: 146
Published: 28 October 2004
10.1159/000082060
EISBN: 978-3-318-01168-5
... Abstract Induction of tolerance has been a longstanding goal in transplantation. Recent preliminarystudies using a steroid-free lymphocyte depletion strategy have been met with great excitementand an equal degree of skepticism. Current studies in this area suggest that immunosuppressioncan...
Book Chapter
Book Chapter
Series: Progress in Respiratory Research
Volume: 31
Published: 08 March 2001
10.1159/000062132
EISBN: 978-3-318-00424-3
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