... Abstract Tobacco smoke contains thousands of organic and inorganic chemicals. Two thirds of these originate from pyrolysis and pyrosynthesis in the burning or smoldering of tobacco products. The rest is transferred unchanged from the tobacco into the smoke. The components in tobacco leaves...

... Abstract Recent years have seen an explosion of animal models of cigarette smoke-inducedchronic obstructive lung disease (COPD). Almost all of these have concentrated on theinduction and prevention of emphysema. Neutrophils and neutrophil elastase,macrophages and macrophage-derived...

... work has been done investigating the mechanisms by which tobaccosmoke and excessive alcohol intake interfere with retinoid metabolism and signaling.Exposure to cigarette smoke subjects tissues to increased reactive oxygen species, which caninduce cytochrome P450 enzymes and result in the degradation...

... Abstract Epidemiologically, it has been suggested that inhalation of cigarette smoke (CS) isclosely associated with increased risk of human cancers in various organs such as the lung,oropharynx, stomach, pancreas, liver and colon. Nevertheless, except for a recent studyshowing that lifetime...

... chapter 1). Though he acknowledged that tobacco smoke had a mystical ability to take hold of the soul, the King laid out his carefully considered arguments against the behavior, suffused them with calls for fealty, patriotism and rationality, and strongly emphasized the anticipated ill effects...