... Abstract Establishing a diagnosis of SjÖgren’s syndrome (SS) has been difficult without sensitive laboratory markers, and in light of the non-specificity of the symptoms of dry eyes and mouth. Rather than complaints about dry eyes or dry mouth, objective symptoms and extraglandular...

... Abstract This chapter summarizes recent advances in the pathogenesis and management of Sjögren's syndrome (SS). Major topics are newly described pathomechanisms and cutaneous manifestations of SS, with special references to hypohidrosis and related mucocutaneous manifestations. Although...

...References References 1. Katayama I, Teramoto N, Arai H, et al: Annular erythema: a comparative study of Sjögren's syndrome with subacute cutaneous lupus erythematosus. Int J Dermatol 1991;30:635-639. 2. Katayama I, Yamamoto T, Otoyama K, Matsunaga T, Nishioka K: Clinical...

..., Bjerrum KB, Braga S, Coll J, de Vita S, et al: Preliminary criteria for the classification of Sjögren's syndrome: results of a prospective concerted action supported by the European Community. Arthritis Rheum 1993;6:340-347 3. Hay EM, Thomas E, Pal B, Hajeer A, Chambers H, Silman AJ: Weak association...

..., European Study Group on Classification Criteria for Sjögren's Syndrome: Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus Group. Ann Rheum Dis 2002;61:554-558. 3. Kassan SS, Moutsopoulos HM: Clinical manifestations...

... 1996;429:139-147. 30. Mandel L, Hong J: HIV-associated parotid lymphoepithelial cysts. J Am Dent Assoc 1999;130:528-532. 31. Fox RI, Luppi M, Pisa P, Kang HI: Potential role of Epstein-Barr virus in Sjögren's syndrome and rheumatoid arthritis. J Rheumatol Suppl 1992;32:18-24. 32. Wen S...

... Abstract Xerostomia is the subjective feeling of oral dryness. The major causes are Sjögren's syndrome (SS), medication and radiotherapy to the head and neck. SS is a chronic systemic autoimmune disease characterized by infiltration of the exocrine glands, the salivary and lacrimal ones...

...., Sjögren's syndrome) and irradiation-induced sialadenitis (head and neck radiotherapy, treatment with radioactive iodine) are discussed in the paper by Delli et al. [this vol., pp. 109-125]. Acute Bacterial Sialadenitis Acute bacterial sialadenitis (ABS) is caused by bacteria invading salivary glands...

... morbidity without oncological compromise. Br J Cancer 2003;89:1610-1613 36. Thomas E, Hay EM, Hajeer A, Silman AJ: Sjögren's syndrome: a community-based study of prevalence and impact. Br J Rheumatol 1998;37:1069-1076 37. Vitali C, Bombardieri S, Jonsson R, Moutsopoulos HM, Alexander EL, Carsons SE...

... could be a source of biochemical data capable of detecting certain diseases. What is even more intriguing is that this phenomenon not only applies to local disorders like oral cancer and Sjögren's syndrome, but distant pathologies like autoimmune, cardiovascular and metabolic diseases as well as viral...

... to gland preservation, the dilemmas in diagnosing and managing tumours of the salivary glands, and the international data collection to understand the aetiology and progression of SjÖgren’s disease. Salivary glands in humans include the paired parotid glands, paired submandibular glands, paired...

... 2008;41:298-312 3. Virtanen T, Konttinen YT, Honkanen N, Härkönen M, Tervo T: Tear fluid plasmin activity of dry eye patients with Sjögren's syndrome. Acta Ophthalmol Scand 1997;75:137-141 4. Choy EP, Cho P, Benzie IF, Choy CK, To TS: A novel porcine dry eye model system (pDEM) with simulated...

... Abstract Background: Conjunctival disorders may adversely affect tear film and promote/induce the development of sicca syndrome (also known as SjÖgren’s syndrome). The basic diagnostics of sicca syndrome are slit lamp examination and functional tests (such as the Schirmer test, break-up time...