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Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 124
Published: 15 June 2022
10.1159/000517387
EISBN: 978-3-318-06296-0
...- and hyperpigmentation, mucous membrane changes and severe changes in mood, diminished activity, hypotonia, and developmental delay are common. Loss of appetite, vomiting, and diarrhea are often present when the child is first seen. Clinical signs of vitamin A deficiency should be sought in each child. Those...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 93
Published: 26 February 2020
10.1159/000503347
EISBN: 978-3-318-06649-4
... Abstract Tackling the global burden of acute malnutrition in children remains a major public health challenge and is essential for achieving sustainable development. Despite having effective treatment options, most wasted children go untreated; treatment coverage for severe acute malnutrition...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494911
EISBN: 978-3-318-06471-1
... Abstract Hyperandrogenism with or without polycystic ovary syndrome can be sustained by an extreme form of insulin resistance (IR), and is thus a secondary form of hyperandrogenism, which may be due to a defect in insulin signal transduction or in the adipose tissue. Severe IR due to adipose...
Book Chapter
Series: Frontiers of Hormone Research
Volume: 51
Published: 04 December 2018
10.1159/000491038
EISBN: 978-3-318-06409-4
... Abstract Familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT) are genetically determined variants of primary hyperparathyroidism. FHH usually has a benign course, and patients do not require treatment, whereas NSHPT is a severe disorder often requiring...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 21 August 2017
10.1159/000475956
EISBN: 978-3-318-06085-0
...How Is Moderately Severe Graves' Orbitopathy Defined? In the consensus statement simultaneously published in the European Journal of Endocrinology and in Thyroid , the journal of the American Thyroid Association (ATA) [ 1 , 2 ], the European Group on Graves...
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 21 August 2017
10.1159/000475958
EISBN: 978-3-318-06085-0
... nerve compression at the orbital apex by enlarged extraocular muscles (apical crowding) or optic nerve stretching because of very severe exophthalmos, most likely but not always associated with optic disc swelling. DON occurs in 3-5% of GO patients [ 1 ]. The pathophysiological mechanism of DON...
Book Chapter
Series: Key Issues in Mental Health
Volume: 179
Published: 01 December 2014
10.1159/000365531
EISBN: 978-3-318-02604-7
... Abstract People with schizophrenia or bipolar disorder have increased morbidity and shortened life expectancy compared with the general population. The prevalence of many physical illnesses is increased in people with severe mental illness and accounts for around three quarters of all deaths...
Book Chapter
Series: Frontiers in Diabetes
Volume: 23
Published: 15 September 2014
10.1159/000362469
EISBN: 978-3-318-02700-6
... Abstract Severe resistance to the metabolic actions of insulin is seen in a range of heterogeneous genetic disorders. Traditionally, linkage studies, homozygosity mapping, and candidate gene sequencing have been the mainstay of efforts to discover the genes harbouring the underlying causal...
Book Chapter
Series: Key Issues in Mental Health
Volume: 178
Published: 01 February 2013
10.1159/000342032
EISBN: 978-3-8055-9989-4
... Abstract People suffering from severe mental illness (SMI), which is defined conventionally in terms of certain diagnoses (such as schizophrenia, bipolar disorder, other psychoses, drug and alcohol dependence and some forms of personality disorder), duration of illness and intensity of contact...
Book Chapter
Published: 22 March 2011
10.1159/000322440
EISBN: 978-3-8055-9673-2
... to be excluded before treating IBD. The severity of Crohn’s disease (CD) can be categorized into three levels: mild, moderate and severe. Severe CD has poor prognosis and is characterized by severe lower gastrointestinal bleeding, intestinal stricture or stenosis, intestinal fistula, severe condition, fever...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 67
Published: 15 February 2011
10.1159/000325578
EISBN: 978-3-8055-9587-2
... and zinc, and the high lactose content also seems to support growth due to a prebiotic effect and improved absorption of minerals. The risk that the use of cow’s milk products suppresses breastfeeding should be prevented by supporting mothers in breastfeeding. There is consensus that children with severe...
Book Chapter
Book Chapter
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 68
Published: 03 May 2010
10.1159/000314565
EISBN: 978-3-8055-9317-5
... Abstract Objectives: Due to their embryological development, auricular atresia and severe microtia are, in most cases, combined malformations. The aims of this study were firstly to develop a surgical technique for combined esthetic and functional reconstruction with a minimum of operations...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 67
Published: 25 November 2009
10.1159/000262603
EISBN: 978-3-8055-9287-1
... Abstract Background/Aims: The aim of this study was to describe audiological outcomes and surgical considerations in electric acoustic stimulation for patients with severe to profound high-frequency hearing loss. Methods: In this latest series of patients in our center, all patients were...
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Book Chapter
Series: Endocrine Development
Volume: 11
Published: 20 November 2007
10.1159/000111067
EISBN: 978-3-8055-8348-0
... Abstract Extreme forms of insulin resistance are a rare cause of type 2 diabetes. However, individualswith severe insulin resistance pose unique diagnostic and therapeutic challenges,and have often acted as ‘experiments of nature’ providing important novel informationregarding endocrine...
Book Chapter