Search Results for severe

... A 64-year-old female with left forefoot deformities – severe hallux valgus with prominent bunion and pronated big toe, crossover second toe with semi-rigid hammer toe, prominent bunionette with medially deviated crossover fifth toe, and transfer metatarsalgia with multiple plantar forefoot...

...- and hyperpigmentation, mucous membrane changes and severe changes in mood, diminished activity, hypotonia, and developmental delay are common. Loss of appetite, vomiting, and diarrhea are often present when the child is first seen. Clinical signs of vitamin A deficiency should be sought in each child. Those...

... Abstract Tackling the global burden of acute malnutrition in children remains a major public health challenge and is essential for achieving sustainable development. Despite having effective treatment options, most wasted children go untreated; treatment coverage for severe acute malnutrition...

... Abstract Hyperandrogenism with or without polycystic ovary syndrome can be sustained by an extreme form of insulin resistance (IR), and is thus a secondary form of hyperandrogenism, which may be due to a defect in insulin signal transduction or in the adipose tissue. Severe IR due to adipose...

... Abstract Familial hypocalciuric hypercalcemia (FHH) and neonatal severe hyperparathyroidism (NSHPT) are genetically determined variants of primary hyperparathyroidism. FHH usually has a benign course, and patients do not require treatment, whereas NSHPT is a severe disorder often requiring...

...How Is Moderately Severe Graves' Orbitopathy Defined? In the consensus statement simultaneously published in the European Journal of Endocrinology and in Thyroid , the journal of the American Thyroid Association (ATA) [ 1 , 2 ], the European Group on Graves...

... nerve compression at the orbital apex by enlarged extraocular muscles (apical crowding) or optic nerve stretching because of very severe exophthalmos, most likely but not always associated with optic disc swelling. DON occurs in 3-5% of GO patients [ 1 ]. The pathophysiological mechanism of DON...

... Abstract People with schizophrenia or bipolar disorder have increased morbidity and shortened life expectancy compared with the general population. The prevalence of many physical illnesses is increased in people with severe mental illness and accounts for around three quarters of all deaths...

... Abstract Severe resistance to the metabolic actions of insulin is seen in a range of heterogeneous genetic disorders. Traditionally, linkage studies, homozygosity mapping, and candidate gene sequencing have been the mainstay of efforts to discover the genes harbouring the underlying causal...

... Abstract People suffering from severe mental illness (SMI), which is defined conventionally in terms of certain diagnoses (such as schizophrenia, bipolar disorder, other psychoses, drug and alcohol dependence and some forms of personality disorder), duration of illness and intensity of contact...

... to be excluded before treating IBD. The severity of Crohn’s disease (CD) can be categorized into three levels: mild, moderate and severe. Severe CD has poor prognosis and is characterized by severe lower gastrointestinal bleeding, intestinal stricture or stenosis, intestinal fistula, severe condition, fever...

... and zinc, and the high lactose content also seems to support growth due to a prebiotic effect and improved absorption of minerals. The risk that the use of cow’s milk products suppresses breastfeeding should be prevented by supporting mothers in breastfeeding. There is consensus that children with severe...

... Abstract Objectives: Due to their embryological development, auricular atresia and severe microtia are, in most cases, combined malformations. The aims of this study were firstly to develop a surgical technique for combined esthetic and functional reconstruction with a minimum of operations...

... Abstract Background/Aims: The aim of this study was to describe audiological outcomes and surgical considerations in electric acoustic stimulation for patients with severe to profound high-frequency hearing loss. Methods: In this latest series of patients in our center, all patients were...

... Abstract Extreme forms of insulin resistance are a rare cause of type 2 diabetes. However, individualswith severe insulin resistance pose unique diagnostic and therapeutic challenges,and have often acted as ‘experiments of nature’ providing important novel informationregarding endocrine...