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Book Chapter
Series: Contributions to Nephrology
Volume: 187
Published: 12 February 2016
10.1159/000442363
EISBN: 978-3-318-05826-0
... Abstract Background: Despite increased understanding of the pathophysiology of septic acute kidney injury (AKI), treatment options are limited, and mortality remains high. Summary: Septic AKI is triggered by pathogen-associated molecular patterns from bacteria and damage-associated...
Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
10.1159/000329238
EISBN: 978-3-8055-9811-8
... with septic AKI had significantly larger hospital mortality rates than patients with nonseptic AKI (29.7 vs. 21.6%, p < 0.001); interestingly, these differences were similar regardless of the severity of the AKI [ 16 ]. Changes in mortality (bar graph) in patients with acute renal failure over the 47...
Book Chapter
Series: Contributions to Nephrology
Volume: 174
Published: 15 September 2011
10.1159/000329246
EISBN: 978-3-8055-9811-8
... Abstract Acute kidney injury (AKI) is a serious condition that affects many intensive care unit (ICU) patients. The most common causes of AKI in the ICU are severe sepsis and septic shock. The mortality of AKI in septic critically ill patients remains high despite our increasing ability...
Book Chapter
Series: Contributions to Nephrology
Volume: 167
Published: 02 June 2010
10.1159/000315924
EISBN: 978-3-8055-9485-1
... in critically ill patients and its association with organ dysfunction and outcome, as well as in septic shock. EA (EAA TM ) was measured within 24 h from onset of refractory septic shock in an intensive care unit. Our study demonstrated that EA level is independent from the type or the source of infection...
Book Chapter
Series: Contributions to Nephrology
Volume: 165
Published: 04 May 2010
10.1159/000313740
EISBN: 978-3-8055-9473-8
... Abstract Septic acute kidney injury (AKI) is the most common form of AKI seen in critically ill patients in developed countries. Its pathogenesis has been traditionally attributed to ischemia secondary to decreased cardiac output and hypotension, which trigger sustained renal vasoconstriction...
Book Chapter
Series: Contributions to Nephrology
Volume: 165
Published: 04 May 2010
10.1159/000313760
EISBN: 978-3-8055-9473-8
... Abstract Intravenous fluids are commonly administered to patients with developing septic acute kidney injury (AKI). Conversely, fluids are just as commonly removed with diuretics or renal replacement therapy (RRT) techniques or ultrafiltration in patients with cardiorenal syndromes (CRS...
Book Chapter
Series: Contributions to Nephrology
Volume: 156
Published: 10 May 2007
10.1159/000102008
EISBN: 978-3-318-01456-3
... to the syndromeof septic AKI, especially in critically ill patients. In such patients, several assumptionsassociated with the ‘pre-renal azotemia paradigm’ are violated. In particular, there is no evidencethat ATN is the histopathological substrate of septic AKI, there is no evidence thaturine tests can...
Book Chapter
Series: Contributions to Nephrology
Volume: 156
Published: 10 May 2007
10.1159/000102080
EISBN: 978-3-318-01456-3
... Abstract Acute kidney injury (AKI) is a common complication of severe sepsis. Severe sepsis isthe most common cause of AKI in ICU. The widely accepted and practiced initial cornerstoneof treatment for septic AKI is fluid resuscitation. The biological rationale for fluid resuscitationin septic...
Book Chapter
Series: Contributions to Nephrology
Volume: 156
Published: 10 May 2007
10.1159/000102127
EISBN: 978-3-318-01456-3
..., and recover the delayed neutrophil apoptosis in septic patients. Thus, cytokineremoval with PMMA-CHDF would be effective for the treatment of severe sepsis and septicshock. ...
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Series: Contributions to Microbiology
Volume: 10
Published: 28 November 2002
10.1159/000068130
EISBN: 978-3-318-00904-0
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Series: Current Studies in Hematology and Blood Transfusion
Volume: 59
Published: 17 December 1991
10.1159/isbn.978-3-318-03529-2
EISBN: 978-3-318-03529-2