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scleroderma

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Book Chapter
Series: Current Directions in Autoimmunity
Volume: 10
Published: 26 May 2008
10.1159/000131502
EISBN: 978-3-8055-8392-3
... Abstract The prototypic autoimmune diseases involving skin (lupus, dermatomyositis) typicallyresult in epithelial injury and autoantibodies to characteristic cellular antigens. Disease-specificautoantibodies are also found in scleroderma, but scleroderma is different from other...
Book Chapter
Book Chapter
Book Chapter
Book Chapter
Series: Current Problems in Dermatology
Volume: 56
Published: 05 July 2023
10.1159/000529557
EISBN: 978-3-318-07040-8
... and invade the segments of the face, trunk and extremities and form dermatomes, replicating the tissue segments . Early on, CREST cells migrate from behind, from the neural crest, and seed a normally hidden linearity in the tissues, which may appear as scleroderma lines , particularly the vertical “en...
Book Chapter
Series: Current Problems in Dermatology
Volume: 56
Published: 05 July 2023
EISBN: 978-3-318-07040-8
..., London: Williams & Williams Company; 1981. 9. Keegan JJ, Garrett FD. The segmental distribution of the cutaneous nerves in the limbs of man. Anat Rec. 1948;102(4):409–37. 10. Serup J. Clinical appearance of skin lesions and disturbances of pigmentation in localized scleroderma. Acta Derm...
Book Chapter
Series: Current Problems in Dermatology
Volume: 50
Published: 01 September 2016
10.1159/000446044
EISBN: 978-3-318-05889-5
..., cutaneous T-cell lymphoma, aquagenic itch, and scleroderma. UV phototherapy is well tolerated, and no significant relationship between UVB therapy and skin cancer has been found. Experimentally, acupuncture has been shown to reduce allergen-related itch, although this finding has been limited by the small...
Book Chapter
Series: Progress in Respiratory Research
Volume: 41
Published: 10 April 2012
EISBN: 978-3-8055-9915-3
..., Champion HC, Girgis RE, Housten-Harris T, Hummers L, Krishnan JA, Wigley F, Hassoun PM: Clinical differences between idiopathic and scleroderma-related pulmonary hypertension.. Arthritis Rheum 2006;54:3043-3050 9. Kawut SM, Taichman DB, Archer-Chicko CL, Palevsky HI, Kimmel SE: Hemodynamics...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445472
EISBN: 978-3-318-05884-0
... Abstract Secondary nephropathies can be associated with disreactive immunological disorders or with a non-inflammatory glomerular damage. In systemic lupus erythematosus (SLE), scleroderma and rheumatoid arthritis as in other connective tissue diseases, kidney volume and cortex echogenicity...
Book Chapter
Series: Frontiers of Gastrointestinal Research
Volume: 33
Published: 25 March 2014
10.1159/000356743
EISBN: 978-3-318-02579-8
... that impaired gut motor activity is one of the primary factors that predisposes to SIBO. Dysmotility is, indeed, the process underlying the development of SIBO in relation to conditions as diverse as scleroderma, diabetes, and intestinal pseudo-obstruction. Small Intestinal Motility and the Irritable Bowel...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
10.1159/000350056
EISBN: 978-3-318-02404-3
... on patients. The list of skin diseases where an assessment of cumulative life course impairment is relevant can be enlarged considerably. Diseases with functional impairment such as, e.g. scleroderma, diseases with prominent subjective symptoms such as acne or hidradenitis, and diseases with limited physical...
Book Chapter
Series: Progress in Respiratory Research
Volume: 41
Published: 10 April 2012
10.1159/000334354
EISBN: 978-3-8055-9915-3
... with scleroderma-associated PAH (SSc-PAH), has been quite discouraging. This chapter reviews the pathophysiology, clinical manifestations, and current and promising therapy for CTD-associated PAH with a particular focus on SSc-PAH. The lack of clinical response to modern therapies may merely reflect...
Book Chapter
Series: Contributions to Nephrology
Volume: 172
Published: 01 September 2011
10.1159/000328859
EISBN: 978-3-8055-9795-1
... and scleroderma-related digital ulcers. Clinical development of ERAs has been hampered by problems with dosing, with the makeup of study cohorts, and adverse events. More recently, a number of studies evaluated the potential of ERA treatment for proteinuric renal disease. Although several ERAs were found...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 27
Published: 01 April 2010
10.1159/000311189
EISBN: 978-3-8055-9331-1
... Abstract Klee’s symptoms, and the rapid progression of the illness, ending with his death after only 5 years, in all probability indicate the rarest but most serious form of scleroderma, known as diffuse systemic sclerosis. Although his skin and internal organs were heavily stricken...
Book Chapter
Series: Current Problems in Dermatology
Volume: 44
Published: 28 May 2013
EISBN: 978-3-318-02404-3
.... Muller H, Rehberger P, Gunther C, Schmitt J: Determinants of disability, quality of life and depression in dermatological patients with systemic scleroderma. Br J Dermatol 2012;166:343-353. 36. Singh MK, Clements PJ, Furst DE, Maranian P, Khanna D: Work productivity in scleroderma: analysis from...
Book Chapter
Series: Current Directions in Autoimmunity
Volume: 10
Published: 26 May 2008
10.1159/000131754
EISBN: 978-3-8055-8392-3
... and lichen planus-like lesions to generalized scleroderma),and paraneoplastic autoimmune dermatoses are discussed as well. ...
Book
Book Chapter
... in systemic lupus erythematosus (SLE), and reviews the studies which are relevant to the use of apheresis in rheumatoid disease. Vasculitis, polymyositis, and scleroderma are mentioned briefly. The nature of rheumatological disorders is such that they have a long time course, are subject to wide fluctuations...
Book Chapter
Series: Contributions to Nephrology
Volume: 172
Published: 01 September 2011
10.1159/000328704
EISBN: 978-3-8055-9795-1
... to support their use in other areas. Scleroderma (systemic sclerosis) is an autoimmune disease of the connective tissues characterized by chronic inflammation and fibrosis with associated vascular damage [ 57 ]. The kidney is commonly involved [ 58 , 59 ], and almost all renal pathology due to scleroderma...
Book Chapter
Series: Contributions to Nephrology
Volume: 172
Published: 01 September 2011
EISBN: 978-3-8055-9795-1
... 56. Dhaun N, Macintyre IM, Melville V, et al: Effects of endothelin receptor antagonism relate to the degree of renin-angiotensin system blockade in chronic proteinuric kidney disease. Hypertension 2009;54:e19-e20 57. Penn H, Howie AJ, Kingdon EJ, et al: Scleroderma renal crisis: patient...