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schizophrenia

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Book Chapter
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 43
Published: 16 October 2018
10.1159/000490450
EISBN: 978-3-318-06394-3
... Abstract In this essay, we propose an association between Franz Kafka's novel, The Trial , and phenomenological and neurobiological processes in schizophrenia. We begin by presenting a summary of the plot, pointing to some of its remarkable literary aspects. We next compare the mental...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 31
Published: 02 August 2017
10.1159/000470802
EISBN: 978-3-318-06051-5
... Abstract Schizophrenia is a disorder that shows a progressive course in 30-50% of the people concerned. The biology of chronification and progression is unclear. Genetic aspects may play a role, but details are unresolved. The fact that immune-mediated and autoimmune disorders...
Book
Book Cover Image
Series: Fast Facts Collection 2006-2015
Published: 09 November 2015
10.1159/isbn.978-1-910797-09-9
EISBN: 978-1-910797-09-9
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358021
EISBN: 978-3-318-02600-9
... Abstract As a multifactorial mental disorder, schizophrenia presents a complex combination of genetic, neurodevelopmental and environmental components. These lead to difficulties in comprehending the molecular basis of schizophrenia as well as in identifying biomarkers. These issues can...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000362429
EISBN: 978-3-318-02600-9
... Abstract The identification of peripheral biomarkers for schizophrenia is of great clinical importance, with the potential to considerably improve its diagnosis, treatment and prognosis. However, despite intense research efforts and the discovery of several potential candidates for markers...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358024
EISBN: 978-3-318-02600-9
... Abstract Schizophrenia is a severe mental disorder characterized by heterogeneous presentation. Owing to its intricate spectrum of symptoms, the current diagnosis of schizophrenia remains subjective, thus representing a serious burden to the healthcare system. Despite recent progress...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358027
EISBN: 978-3-318-02600-9
... Abstract It has become clear that glial cells play a major role in the pathophysiology of schizophrenia. There are three main glial cell populations in the brain, (1) astrocytes, (2) oligodendrocytes and (3) microglia, and all three glial populations have been implicated in this disorder...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358028
EISBN: 978-3-318-02600-9
... currently employed for protein separation and protein identification will dramatically increase the number of proteomics-based schizophrenia research studies. The advent of high-throughput techniques allows scientists to quantify complex biological mixtures, such as postmortem brain, and to identify...
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 31
Published: 07 March 2013
10.1159/000345527
EISBN: 978-3-318-02272-8
... provides the first complete and convincing description of schizophrenia - 69 years before Kraepelin fully developed the concept of dementia praecox and 76 years before Bleuler coined the word ‘schizophrenia'. We consider the history of the concept of schizophrenia and the intriguing possibility...
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 28
Published: 27 February 2013
10.1159/000343972
EISBN: 978-3-318-02311-4
... Abstract Throughout the last 20 years, numerous studies have indicated pro-inflammatory activity in patients with an acute schizophrenic episode. In this report, the most relevant findings concerning the cytokine systems in schizophrenia are demonstrated, together with recent studies on gene...
Book
Book Cover Image
Series: Advances in Biological Psychiatry
Volume: 26
Published: 29 July 2010
10.1159/isbn.978-3-8055-9512-4
EISBN: 978-3-8055-9512-4
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 101
Published: 03 May 2010
10.1159/000314518
EISBN: 978-3-8055-9428-8
... Schizophrenia is a major psychiatric brain disease with potentially devastating effects. It strikes in adolescence and young adulthood and can last a lifetime. It affects about 1% of the world's population, is destructive for the individual, family and society, and constitutes a major costly...
Book Chapter
Series: Monographs in Human Genetics
Volume: 18
Published: 15 February 2010
10.1159/000287602
EISBN: 978-3-8055-9281-9
.... Over the past two years, cohorts of patients with apparently distinct neuropsychiatric phenotypes such as autism and schizophrenia have also been analyzed for CNVs using genome wide detection methods and chromosomal abnormalities were detected in a significant amount of cases. Surprisingly, mutual...
Book Chapter
Series: Key Issues in Mental Health
Volume: 177
Published: 03 February 2010
10.1159/000284376
EISBN: 978-3-8055-9339-7
... Abstract Over a decade of research has shown that neurocognition and social cognition are highly relevant to functional outcome in schizophrenia. These 2 factors can function as predictors, mediators or moderators of functioning under various conditions. One purpose of this chapter...
Book Chapter
Series: Key Issues in Mental Health
Volume: 177
Published: 03 February 2010
10.1159/000284380
EISBN: 978-3-8055-9339-7
... Abstract Training microskills of emotional intelligence may be a promising opportunity to improve functional recovery in schizophrenia. The chapter details the different components of emotional intelligence and discusses its relevance in the treatment of schizophrenia. The modules...
Book Chapter
Series: Key Issues in Mental Health
Volume: 177
Published: 03 February 2010
10.1159/000284385
EISBN: 978-3-8055-9339-7
... Abstract This chapter reviews the role of motivation in learning outcomes, a relevant topic for cognitive remediation programs which seek to enhance learning of neuropsychological skills. The literature indicates that people with schizophrenia who participate in cognitive remediation are more...
Book
Book Cover Image
Series: Key Issues in Mental Health
Volume: 177
Published: 03 February 2010
10.1159/isbn.978-3-8055-9339-7
EISBN: 978-3-8055-9339-7
Book Chapter
Series: Modern Trends in Psychiatry
Volume: 26
Published: 13 January 2009
10.1159/000189771
EISBN: 978-3-8055-9002-0
... Abstract Physical ill health is a common feature of schizophrenia. Hypertension, elevated cholesterol, obesity and type 2 diabetes are common occurrences and lead to increased morbidity and mortality. The question therefore arises whether these changes are due to an unhealthy life style...