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Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 84
Published: 31 August 2020
10.1159/000457932
EISBN: 978-3-318-06670-8
... Abstract Squamous cell carcinoma (SCC) is one of the most common malignant neoplasms involving the anterior skull base, resulting from local invasion from an adjacent anatomical region. The primary sites of origin are most frequently the nasal cavity and paranasal sinuses, and less often...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366534
EISBN: 978-3-318-02763-1
... Abstract This manuscript focuses on the use of mice to study the genetics and biology of cutaneous squamous cell carcinoma (SCC). Mice develop actinic keratosis-like lesions and SCC resembling those seen in humans. As an animal model, the mouse provides great experimental flexibility and has...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 77
Published: 29 April 2016
10.1159/000441884
EISBN: 978-3-318-05651-8
... are thought to have critical but contrasting roles through facilitating antitumor immunity and inducing oncogenic factors. However, the role and function of inflammasomes in oropharyngeal carcinoma remain unclear. We analyzed nine specimens of oropharyngeal squamous cell carcinoma (SCC) and determined...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366533
EISBN: 978-3-318-02763-1
... Abstract The link between actinic keratosis (AK), squamous cell carcinoma (SCC), and a fully functional immune system has been frequently observed but is poorly understood. Elderly and immunosuppressed individuals and those with weakened immune systems caused by disease are all at increased...
Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
EISBN: 978-3-318-06608-1
... and in vitro assessment of UVA protection by sunscreen formulations containing either butyl methoxy dibenzoyl methane, methylene bis-benzotriazolyl tetramethylbutylphenol, or microfine ZnO. Int J Cosmet Sci. 2002;24(3):170–85. doi: 10.1046/j.1467-2494.2002.00137.x 13. SCCS. Opinion of the scientific...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 79
Published: 03 August 2016
10.1159/000445137
EISBN: 978-3-318-05854-3
... , 20 ]. One initial hypothesis for extraoral T2R receptors that justified their widespread distribution in the body was that they bind bitter products from pathogenic bacteria or fungi. This theory was supported by early studies of mouse nose contains solitary chemosensory cells (SCCs), which...
Book Chapter
Series: Developments in Ophthalmology
Volume: 40
Published: 27 February 2007
10.1159/000100348
EISBN: 978-3-318-01444-0
... Abstract The vestibulo-ocular reflex (VOR) ensures best vision during head motion by movingthe eyes contrary to the head to stabilize the line of sight in space. The VOR has three maincomponents: the peripheral sensory apparatus (a set of motion sensors: the semicircularcanals, SCCs...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366535
EISBN: 978-3-318-02763-1
... lesions. Cutaneous squamous cell carcinoma (SCC) is the most frequent malignancy found in solid OTRs[ 2 , 3 , 4 , 5 , 6 , 7 , 8 ]. The risk of developing SCC in this population is up to 65- to 250-fold higher than in the general population, and SCC occurs roughly fifteen years earlier in OTRs [ 5 , 7 , 8...
Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
10.1159/000517632
EISBN: 978-3-318-06608-1
... to the definitions of the Scientific Committee on Consumer Safety (SCCS) or the European Pharmacopoeia, ZnO is insoluble or practically insoluble (<100 ng/mL), respectively. Nevertheless, dissolved Zn species can be detected in quantities below the above definition of insoluble or practically insoluble. Since...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366532
EISBN: 978-3-318-02763-1
... Abstract Squamous skin cancer, which is commonly called squamous cell carcinoma (SCC), represents an immunological puzzle. The major skin cancers (SCC, basal cell carcinoma, Merkel cell carcinoma, and melanoma) and actinic keratosis (AK), as a potential precursor lesion of SCC, are common...
Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
10.1159/000517595
EISBN: 978-3-318-06608-1
... of Consumer Safety (SCCS) [ 20 ], a committee jointly organized under the Directorate-General for Internal Market, Industry, Entrepreneurship and Small Businesses and DG Health and Food Safety, issues a scientific opinion on the safety of an ingredient on behalf of the EU Commission. Assessments tend...
Book Chapter
Series: Current Problems in Dermatology
Volume: 55
Published: 29 November 2021
EISBN: 978-3-318-06608-1
... of the European Parliament and of the Council of 30 November 2009 on cosmetic products (version 1.8.2018). Available from: https://eur-lex.europa.eu/legal-content/EN/TXT/PDF/?uri=CELEX:02009R1223–20180801&from=FR, viewed September 6, 2020. 20. SCCS. Scientific Committee on Consumer Safety (SCCS...
Book Chapter
Series: Current Problems in Dermatology
Volume: 43
Published: 29 February 2012
10.1159/000335152
EISBN: 978-3-8055-9856-9
... is recommended before receiving a transplant to screen and treat skin disease, in particular for warts, actinic keratosis (AK), Bowen's disease (BD), and squamous cell carcinoma of the skin (SCC). The patient’s risk for developing skin cancer (level D recommendation) should be assessed (level D recommendation...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366536
EISBN: 978-3-318-02763-1
...-brown over time. These lesions are often clinically indistinguishable from intraepidermal carcinoma (IEC) or superficial squamous cell carcinoma (SCC). Proliferative Actinic Keratosis Proliferative AKs are usually found on the face and are often greater than 1 cm in diameter [ 12...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000367959
EISBN: 978-3-318-02763-1
... early squamous cell carcinoma (SCC) in situ , although debate over their classification continues. Anti-EGFR therapies have been approved for the treatment of several malignancies and are undergoing trials for others [<citeref rid="ref1">1</citeref>], including advanced cutaneous squamous...
Book Chapter
Series: Aesthetic Dermatology
Volume: 3
Published: 09 February 2016
10.1159/000439342
EISBN: 978-3-318-02557-6
... of nonmelanoma skin cancers (NMSCs) are kept, younger patients are reported to be increasingly affected by NMSC [ 17 ]. However, recent reports from Australia show a decreased incidence of basal cell (BCCs) and squamous cell cancers (SCCs) of the skin in men and women younger than 45 years [ 5 ]. This decrease...
Book Chapter
Series: Current Problems in Dermatology
Volume: 43
Published: 29 February 2012
10.1159/000335151
EISBN: 978-3-8055-9856-9
... Abstract As squamous cell cancer (SCC) is the most common malignancy in organ transplant recipients, a viral etiology has been proposed. Human papillomavirus (HPV) is found more often in organ transplant recipients than in the general population, but its role in cancer development has been...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366538
EISBN: 978-3-318-02763-1
... that extend with finger-like projections into the upper dermis or down the hair follicles or acrosyringia. This variant is called proliferative AK and is very difficult to distinguish from a squamous cell carcinoma (SCC) [ 2 , 7 , 8 , 11 .] Similar to cervical intraepithelial neoplasia and vaginal...
Book Chapter
Series: Current Problems in Dermatology
Volume: 43
Published: 29 February 2012
10.1159/000335144
EISBN: 978-3-8055-9856-9
...) are at significantly increased risk to develop a wide variety of skin cancers, particularly epithelial skin cancer, Merkel cell carcinoma and Kaposi's sarcoma (KS) [ 1 , 2 ]. Squamous cell carcinoma (SCC) and basal-cell carcinoma (BCC) account for more than 90% of all skin cancers in OTR [for review see 3...
Book Chapter
Series: Current Problems in Dermatology
Volume: 43
Published: 29 February 2012
10.1159/000335137
EISBN: 978-3-8055-9856-9
... numbers with a 65- to 100-fold increase for squamous cell carcinoma (SCC) as compared to the general population [ 2 ]. The two main driving forces behind this increase are photodamage by ultraviolet light and the use of immunosuppressants. The effects of either photodamage or immunosuppressant or both...