.... Sarcopenia is one of the principal reasons for or triggers of frailty. It is a disease setting showing decreased muscle volume and quality associated with decreased physical function or quality of life. Recent mean age at dialysis therapy induction is getting near to 70 years old in Japan. Japanese dialysis...

..., sarcopenia, cognitive decline, depression, and cardiovascular disease. However, the evidence to prove the presence of a possible effect of vitamin D supplementation on age-related diseases is for the most part inconsistent or inconclusive. This chapter reviews and discusses the possible effects of vitamin D...

... Abstract Aging is characterized by the catabolism of muscles leading to sarcopenia and frailty. These are two geriatric syndromes with partly overlapping phenotypes. Primary sarcopenia, i.e. loss of muscle mass and function related to aging alone, usually precedes frailty. Thus, robustness...

... Abstract Sarcopenia is a syndrome characterized by the progressive loss of muscle mass and strength with a risk of undesirable effects such as physical disability, poor quality of life and death, and it is a major contributing factor of disability and loss of independence in the elderly. Its...

... Abstract Aging is associated with significant decline in neuromuscular function and performance. Sarcopenia, often defined as age-related loss of muscle mass, strength, and functional decline, is the most characteristic feature of age-related changes in the neuromuscular system. Strength...

... Abstract Sarcopenia is an age-related structural and functional impairment of skeletal muscle leading to loss of strength, contractile capacity and endurance. Among factors implicated in sarcopenia, deregulation of muscle protein synthesis (MPS) has frequently been reported. Thus, the attempts...

... Abstract Understanding age-related sarcopenia and, more importantly, devising counterstrategies require an intimate knowledge of the underlying mechanism(s) of sarcopenia. The mitochondrial theory of aging (MTA) has been a leading theory on aging for the last decade; however...

... of this change is the age-associated decline in skeletal muscle mass and function (sarcopenia). Sarcopenia has been linked to declines in physical function, loss of independence, and mortality. The functional declines associated with sarcopenia are factors that contribute to the syndrome of frailty...

...References References 1. Jeste DV, Savla GN, Thompson WK, et al: Association between older age and more successful aging: critical role of resilience and depression. Am J Psychiatry 2013;170:188-196. 2. Rosenberg IH: Sarcopenia: origins and clinical relevance. J Nutr 1997;127(5 suppl...

...References References 1. Elia M, Zellipour L, Stratton R: To screen or not to screen for adult malnutrition. Clin Nutr 2005;24:867-884 2. Cruz-Jentoft A, Baeyens JP, Bauer JM, et al: Sarcopenia: European consensus on definition and diagnosis. Report of the European Working Group...

...References References 1. Morley JE, von Haehling S, Anker SD, Vellas B: From sarcopenia to frailty: a road less traveled. J Cachexia Sarcopenia Muscle 2014;5:5-8. 2. Kelaiditi E, Cesari M, Canevelli M, et al: Cognitive frailty: rational and definition from an (I.A.N.A./I.A.G.G...

... for nursing home entry in the EU, a period that is crucial to promote useful interventions. Slow gait speed, cognitive decline, weight loss, sarcopenia, undernutrition, and vision and hearing impairments are common in this population [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 ]. It is also important to note...

... factors include sedative or antihypertensive medication, loss of muscle mass (sarcopenia), and the fear of falling. Many elderly persons have multiple risk factors at the same time. Treatable components include benign paroxysmal positional vertigo that can be effectively treated with specific physical...

..., Topinkova E, Vandewoude M, Zamboni M: Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older People. Age Ageing 2010;39:412-423. 9. Fahal IH, Bell GM, Bone JM, Edwards RH: Physiological abnormalities of skeletal muscle in dialysis patients...

... and the potential for prevention and treatment are beginning to be explored. Frailty is multifactorial with aging, comorbidity, sarcopenia, and endocrine immune dysfunction contributing to the condition. Falling testosterone levels with advancing age are associated with muscle loss (sarcopenia) and strength. Among...

... that an increase in dietary protein intake might increase the muscle mass, but this study had certain limitations. Future interventional studies will be needed to investigate whether increases in protein intake have a beneficial effect on sarcopenia, protein-energy wasting, and frailty. The older dialysis...

... unit number estimate after cerebral infarction. J Neurol Sc 2006;250:27-32 5. Scherbakov N, Doehner W: Sarcopenia in stroke - facts and numbers on muscle loss accounting for disability after stroke. J Cachex Sarcopenia Muscl 2011;2:5-8 6. Korpelainen JT, Sotaniemi KA, Myllylä VV: Autonomic...

.... Meehan M, Penckofer S: The role of vitamin D in the aging adult. J Aging Gerontol 2014;2:60-71. 8. Cruz-Jentoft AJ, Baeyens JP, Bauer JM, Boirie Y, Cederholm T, Landi F, et al: Sarcopenia: European consensus on definition and diagnosis: report of the European Working Group on Sarcopenia in Older...

... Aging and Sarcopenia in C. elegans Sarcopenia in Feeding and Locomotory Muscles In addition to increased adiposity, loss of muscle mass is a major body composition change of human aging. This loss of muscle mass is named sarcopenia and the causes remain mysterious, although they are likely...