... Abstract Acute kidney injury (AKI) is a common complication among critical illnesses. In severe cases, renal replacement therapy (RRT) is required. It has been reported that hospital mortality of the patients who require RRT is more than 60%. Because of the high mortality, it is quite important...

... Abstract Renal replacement therapy (RRT) is increasingly utilized to support critically ill patients with severe acute kidney injury (AKI). The clinical dilemma of when to ideally start RRT in these patients has been a longstanding issue that is in need of higher quality evidence to guide...

... Abstract Background: Renal replacement therapy (RRT) is commonly and increasingly utilized in critically ill patients with severe acute kidney injury (AKI). The issue of when to start RRT in a critically ill patient with AKI has long troubled clinicians. Summary: Currently...

... Abstract Critically ill patients whose course is complicated by acute kidney injury (AKI) often commence renal replacement therapy (RRT). For these patients, initiation of RRT results in a measurable escalation in both the complexity and associated costs of care. While RRT is commonly used...

... Abstract Renal replacement therapy (RRT) is a form of extracorporeal support for critical patients, especially for those with acute kidney injury. This therapy enables to gain adequate control over the great metabolic and fluids demand when kidneys are not able to do so; this condition...

... Abstract All aspects of current treatment of acute kidney injury (AKI), including renal replacement therapy (RRT), are basically supportive. Emergent RRT is indicated in the management of AKI with refractory pulmonary edema, hyperkalemia or metabolic acidosis, or when uremic symptoms or signs...

... Abstract Renal replacement therapy (RRT) is an important therapeutic and supportive measure for acute kidney injury (AKI) in the critical care setting. While RRT is extensively used in clinical practice, there remains uncertainty about the ideal circumstances of when to initiate RRT...

... and update of definition in AKI, the incidence of CSA-AKI ranges between 8.9 and 39% [ 1 , 2 ]. And about 1-5% developed severe AKI for which renal replacement therapy (RRT) was needed [ 3 ]. The consensus definitions of AKI were based on 1.5- to 2-fold increases in serum creatinine (SCr) [ 4...

... Excellence (NICE) [ 4 ] all strive to make better prevention and management of CSA-AKI care. In recent years, as defined by different criteria, the incidence of CSA-AKI ranges between 20 and 40% [ 5 , 6 ], and 1.6-5.8% of them need RRT [ 7 ]. In a systematic review and meta-analysis, Hu et al. [ 7 ] showed...

... Abstract World wide, heparins are the most commonly used anticoagulants for renal replacementtherapy (RRT). In the intensive care unit (ICU) keeping the RRT circuit patent is more difficultthan during routine outpatient hemodialysis, as ICU patients typically have sepsis and/orinflammation...

... extrapulmonary manifestations commonly occur, and a substantial proportion of patients with severe COVID-19 exhibit signs of kidney damage. Clinically, kidney involvement ranges from mild/moderate proteinuria and hematuria to acute kidney injury (AKI) requiring renal replacement therapy (RRT...

... Abstract Background: Current practices for renal replacement therapy (RRT) in ICU remainpoorly defined. The observational DOse REsponse Multicentre International collaborativeinitiative (DO-RE-MI) survey addresses the issue of how the different modes of RRT are currentlychosen and performed...

... Abstract Acute kidney injury (AKI) is a process that can lead to renal failure. No biologicalmarkers are available for predicting the cause or prognosis of AKI. Tests that can predictwhich patients will need renal replacement therapy (RRT) are needed. In this chapter, wereview the recent...

... Abstract Background: The practice of renal replacement therapy (RRT) has reached an optimalstandard of care worldwide. Nevertheless, some aspects of acute renal failure treatment andsupport still present wide variability between different centers. This is especially true for themode and dose...

... replacement therapy (RRT). The metabolic situation is not only affected by renal dysfunction and the type and intensity of RRT, but also by the underlying disease process and associated complications. Nevertheless, renal failure per se is associated with a broad spectrum of specific metabolic alterations...

... of supportive cares that do not target the mechanisms of tissue injury: for this reason, several clinical trials aimed at selectively blocking “the magic bullet” involved in sepsis-associated tissue injury failed [ 4 ]. Furthermore, classical renal replacement therapies (RRTs) are not associated...

... Abstract Background: End-stage renal disease (ESRD) in children is considered a rare but serious condition. Information on the epidemiology, demographics, treatment modality at the start of renal replacement therapy (RRT), and mortality of pediatric patients with ESRD is essential...

... Abstract Adequate selection of the modality of renal replacement therapy (RRT), ideally based on well-planned predialysis care, informed decision by the patient and timely initiation of dialysis, is essential to optimize the outcome of patients with chronic kidney disease. However...

... patients, especially in those with acute kidney injury, and positive or negative fluid balance (FB) is common. Indeed, positive FB is reported in up to 40% of patients admitted to the Intensive Care Unit [ 1 ]; and among critically ill patients receiving renal replacement therapy (RRT), more than two...