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Book Chapter
Series: Monographs in Human Genetics
Volume: 20
Published: 26 April 2016
10.1159/000444570
EISBN: 978-3-318-05856-7
... that further supports the promise of gene therapy approaches to improving hearing health. These studies document that both replacing an absent gene and downregulating a dominant mutated gene can restore hearing. It is thus reasonable to predict that the successful treatment approaches increasingly being...
Book Chapter
Series: Developments in Ophthalmology
Volume: 53
Published: 22 April 2014
10.1159/000358531
EISBN: 978-3-318-02585-9
... study, including visual cycle inhibitors [ 2 , 3 ], complement inhibitors [ 1 ], and neurotrophic factors [ 4 ]. A preliminary report of a patient with Stargardt disease [ 5 ] indicates that retinal pigment epithelium (RPE) transplants might preserve or restore vision in conditions where dysfunctional...
Book Chapter
Series: Medicine and Sport Science
Volume: 59
Published: 17 October 2012
10.1159/000341958
EISBN: 978-3-8055-9993-1
... the rehydration success of the drink. It is well known that addition of sodium and some other nutrients to rehydration drinks enhances fluid balance restoration after exercise, but the effects of milk proteins have been less well documented. Skimmed milk is an effective post-exercise rehydration solution...
Book Chapter
Series: Advances in Oto-Rhino-Laryngology
Volume: 66
Published: 26 May 2009
10.1159/000218208
EISBN: 978-3-8055-9036-5
... Abstract Strategies to restore sensorineural hearing loss focus on the replacement of lost hair cells, the specialized mechanoreceptors in the organ of Corti that convert the mechanical energy of sound into electrical energy. Hair cells in mammalian systems do not have the capacity...
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Book Chapter
Series: Monographs in Oral Science
Volume: 27
Published: 24 September 2018
10.1159/000487836
EISBN: 978-3-318-06369-1
... Abstract Atraumatic restorative treatment (ART) is a method of managing dental caries based on 2 pillars: sealants for preventing carious lesions in pits and fissures, and restorations for cavitated dentine carious lesions. ART uses only hand instruments for opening/enlarging the cavity...
Book Chapter
Series: Monographs in Oral Science
Volume: 29
Published: 12 January 2021
10.1159/000510191
EISBN: 978-3-318-06852-8
... Abstract Biofilm formation depends on many factors, one of them being the surface (substrate) on which the biofilm is formed, and dental restorative materials are such substrates. Biofilms play a crucial role for caries formation and inflammation of gingival, periodontal, or mucosal tissues...
Book Chapter
Series: Monographs in Oral Science
Volume: 27
Published: 24 September 2018
10.1159/000487831
EISBN: 978-3-318-06369-1
... Abstract Restoring carious lesions can be challenging, especially for deep lesions in proximity to the pulp. A number of factors can influence restoration longevity. This chapter will discuss aspects that should be considered when restoring carious lesions. In the first part, factors that might...
Book Chapter
Series: Monographs in Oral Science
Volume: 20
Published: 10 May 2006
10.1159/000093364
EISBN: 978-3-318-01331-3
.... As a result of the improvements in composite restorative materials, and inadhesive techniques, it has become possible to rehabilitate eroded dentitions in a less invasivemanner. However, even today advanced erosive destruction requires the placement ofmore extensive restorations such as ceramic veneers...
Book Chapter
Series: Monographs in Oral Science
Volume: 25
Published: 24 June 2014
10.1159/000360562
EISBN: 978-3-318-02553-8
.... As a result of the improvements in resin composite restorative materials, and in adhesive techniques, it has become possible to rehabilitate eroded dentitions in a less invasive manner. However, even today advanced erosive destruction requires the placement of more extensive restorations such as overlays...
Book Chapter
Series: Monographs in Oral Science
Volume: 26
Published: 16 October 2017
10.1159/000479353
EISBN: 978-3-318-06113-0
... Abstract This chapter describes the clinical performance of restorations placed in root caries lesions. The prevalence of root caries and other types of cervical lesions, caused by abfraction, erosion, and abrasion (non-carious cervical lesions) are high, mainly in the elderly; and therefore...
Book Chapter
Series: Monographs in Oral Science
Volume: 30
Published: 08 March 2022
10.1159/000520787
EISBN: 978-3-318-06913-6
... on the longevity of dental restorations has focused almost solely on the technical aspects needed to improve the adhesive properties and longevity of the restorations. Studying the possible individual variations in the quality of dental tissue may enable further developments targeting specific dental tissue...
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