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Book Chapter
Series: Current Problems in Dermatology
Volume: 56
Published: 05 July 2023
EISBN: 978-3-318-07040-8
... of action are identical for cosmetic and medical tattooing, the regulatory requirements are separated in two divergent regulative frameworks. Abstract This chapter explains the international regulative framework on equipment and inks for cosmetic and medical tattooing. In the following text...
Book Chapter
Book Chapter
Series: Progress in Neurological Surgery
Volume: 34
Published: 28 May 2019
EISBN: 978-3-318-06422-3
... Abstract The medical uses of radioactive material are heavily regulated and require a license issued by either the Nuclear Regulatory Commission or an Agreement State. Regulations also require that specific safety checks and calibrations are performed on the Gamma Knife device as part...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 88
Published: 30 May 2017
EISBN: 978-3-318-06031-7
... Abstract Human milk oligosaccharides are key components of human milk and appear in various compositions and concentrations in all human milks. In regulatory sense human milk oligosaccharides are classified as novel foods or novel food ingredients requiring safety assessment. In addition...
Book Chapter
Series: Developments in Ophthalmology
Volume: 55
Published: 27 October 2015
EISBN: 978-3-318-05565-8
... savings which accrue from their clinical benefit. This chapter will discuss the financial and regulatory issues associated with retinal drugs. Financial Implications The financial implications of physician-administered drugs can be considered from both a microeconomic and macroeconomic perspective...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 18
Published: 17 November 2014
EISBN: 978-3-318-02736-5
... and further legal/regulatory initiatives are ongoing and have led to an increase of studies planned for neonates. However, even more efforts specifically for the most vulnerable and heterogeneous population of preterm infants is needed. Introduction Until a few decades ago, the sales and advertising...
Book Chapter
Series: Developments in Ophthalmology
Volume: 53
Published: 22 April 2014
EISBN: 978-3-318-02585-9
... agencies (EMA) and the relevant authority in the USA (FDA) have made significant efforts to establish regulatory guidance for use in the application of the cell-based therapies for human patients. The guidelines surrounding cell-based therapy take into account the current legislation, but focus less...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 99
Published: 21 October 2013
EISBN: 978-3-318-02481-4
... Abstract Regulatory T cells (Treg cells) are crucial in mediating immune homeostasis and promoting the establishment and maintenance of peripheral tolerance. Excess body weight and obesity are typified by ‘low-degree' chronic inflammation and are associated with an increased risk...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 106
Published: 12 February 2013
EISBN: 978-3-318-02266-7
... to be registered and dossiers have to be reviewed and approved by regulatory agencies (e.g. FDA, EFSA) before a new product can be introduced. Growth studies should include the period of exclusive feeding of a new or renovated infant formula (i.e. until 4-6 months of age). A long-term follow-up is under debate...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 28
Published: 23 April 2012
EISBN: 978-3-8055-9803-3
... Abstract Recent progress in understanding the neurobiology and pathophysiology of Alzheimer’s disease (AD) has fostered new interest for more efficacious symptomatic treatments as well as for disease-modifying approaches based on these insights. This has many implications for regulatory...
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
EISBN: 978-3-8055-9687-9
... Abstract Regulatory T (T reg ) cells play a pivotal role in immune suppression and are integral to the control of allergic responses. The chronic inflammatory skin condition atopic dermatitis (AD) is severest in patients who are sensitized to allergens from diverse sources including foods...
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
EISBN: 978-3-8055-9687-9
... is in an impaired epidermal barrier function, alternative hypotheses include an imbalance between antiviral immune responses and regulatory T (T reg ) cells, and the defects in the innate immune system. Eczema herpeticum (EH) occurs almost exclusively in patients with AD, particularly in those who fail to control...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 66
Published: 22 July 2010
EISBN: 978-3-8055-9455-4
... innovation. However, more and more stringent regulations are developed, all based on the general principles adopted by the Codex Alimentarius Commission. In addition to the different regulatory processes and administrative requirements according to the country, the high level (and cost) of scientific...
Book Chapter
Series: Current Directions in Autoimmunity
Volume: 11
Published: 18 February 2010
EISBN: 978-3-8055-9384-7
... Abstract TNF-Α (TNF) is a pleiotropic cytokine which can have proinflammatory or immunosuppressive effects, depending on the context, duration of exposure and disease state. The basis for the opposing actions of TNF remains elusive. The growing appreciation of CD4+FoxP3+ regulatory T cells...
Book Chapter
Series: Forum of Nutrition
Volume: 63
Published: 10 December 2009
EISBN: 978-3-8055-9301-4
... of substances between the CNS and blood. Many of the eating-related peptides and regulatory proteins produced by peripheral tissues and with receptors in the brain have been found to cross the BBB. The consequences of BBB permeability to these substances can be viewed from various perspectives. Here, we briefly...
Book Chapter
Series: Frontiers in Diabetes
Volume: 20
Published: 24 November 2009
EISBN: 978-3-8055-9276-5
.... It describes how activation of Müller glia by pro-inflammatory and pro-angiogenic factors may contribute to the development of neovascularisation and fibrosis, the characteristic pathological features of diabetic retinopathy. The chapter also highlights the regulatory role that Müller glia exert in various...
Book Cover Image
Series: Nestlé Nutrition Institute Workshop Series: Clinical & Performance Program
Volume: 12
Published: 07 August 2009
EISBN: 978-3-8055-8978-9
Book Chapter
Series: Frontiers of Neurology and Neuroscience
Volume: 25
Published: 31 March 2009
EISBN: 978-3-8055-9024-2
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 94
Published: 10 September 2008
EISBN: 978-3-8055-8629-0
... Abstract Foxp3-expressing regulatory T cells (Tregs) have an essential function of preventing autoimmune disease in man and mouse. Foxp3 binds to forkhead motifs of about 1,100 genes and the strength of binding increases upon PMA/ionomycin stimulation. In Foxp3-expressing T-cell hybridomas...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 94
Published: 10 September 2008
EISBN: 978-3-8055-8629-0
... Abstract CD4+CD25+ natural regulatory T (nTR) lymphocytes represent a separate, thymus-derived T-cell lineage that is essential to the maintenance of immunological tolerance in the host. Their deficiency or dysfunction has been implicated in the pathogenesis of allergic and autoimmune diseases...