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Book Chapter
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
10.1159/000323305
EISBN: 978-3-8055-9687-9
... Abstract Regulatory T (T reg ) cells play a pivotal role in immune suppression and are integral to the control of allergic responses. The chronic inflammatory skin condition atopic dermatitis (AD) is severest in patients who are sensitized to allergens from diverse sources including foods...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 91
Published: 20 January 2006
10.1159/000090279
EISBN: 978-3-318-01266-8
... Abstract Activation-induced cell death, anergy and/or immune response modulation by T regulatorycells (T Reg ) are essential mechanisms of peripheral T-cell tolerance. There is growingevidence that anergy, tolerance and active suppression are not entirely distinct, but rather,represent linked...
Book Chapter
Series: Nestlé Nutrition Institute Workshop Series
Volume: 79
Published: 10 September 2014
10.1159/000360685
EISBN: 978-3-318-02670-2
... + gut-tropic T REG . In contrast, microbiota-specific T REG in the colon do not appear to require RA, but can be regulated by short-chain fatty acids (SCFA), microbial metabolites that signal through the G protein-coupled receptor GPR43. Moreover, T REG do not need CCR9 to home to the colon...
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
10.1159/000323299
EISBN: 978-3-8055-9687-9
... expressions including γ-interferon and IL-12 are elevated in the chronic lesions as well as elevated Th2 cytokines in the acute AD lesions. The discovery of Th17 lineage and regulatory T (T reg ) cells shifted the simple Th1/Th2 balance concept into a 4-way balance system. Th17/22 cells, Foxp3+ T reg and IL...
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 12
Published: 20 May 2008
10.1159/000129063
EISBN: 978-3-8055-8527-9
... toleranceincluding suppression by regulatory T cells (Treg). In addition,a key role in the gut homoeostasis is sustained by immunosuppressivecytokines, such as interleukin (IL)-10 and transforminggrowth factor (TGF) Β , released by T reg. Coeliacdisease is a common, and almost worldwide spread, intoleranceto wheat...
Book Chapter
Series: Current Problems in Dermatology
Volume: 41
Published: 09 May 2011
10.1159/000323306
EISBN: 978-3-8055-9687-9
... is in an impaired epidermal barrier function, alternative hypotheses include an imbalance between antiviral immune responses and regulatory T (T reg ) cells, and the defects in the innate immune system. Eczema herpeticum (EH) occurs almost exclusively in patients with AD, particularly in those who fail to control...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 92
Published: 24 January 2007
10.1159/000099263
EISBN: 978-3-318-01404-4
... inflammation in the eye. Among these is the generation of regulatoryT (T reg) cells, which act to prevent the induction and expression of T cell inflammation.At least four different pathways exist for the development of ocular Treg cells. The redundancyin the generation of T reg cells is a testament...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 91
Published: 20 January 2006
10.1159/000090230
EISBN: 978-3-318-01266-8
.... Several Th2 cytokines have potential to modulate airway inflammation,in particular interleukin-13 which induces airway hyperresponsiveness independently of IgEand eosinophilia in animal models. The identification of transcription factors controllingTh1, Th2 and T-regulatory cell (T Reg ) development...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 91
Published: 20 January 2006
10.1159/000090282
EISBN: 978-3-318-01266-8
... characterized mainly by suppressed proliferative and cytokine responses against themajor allergens and its T-cell recognition sites. It is initiated by autocrine action of IL-10and/or TGF-Β, which are increasingly produced by the antigen-specific T Regulatory (T Reg )cells. Tolerized T cells can be reactivated...
Book Chapter
Series: Chemical Immunology and Allergy
Volume: 91
Published: 20 January 2006
10.1159/000090280
EISBN: 978-3-318-01266-8
... toleranceinduced by T regulatory (T Reg ) cells in several pathways. The diverse effects of histamine onimmune regulation are due to differential expression and regulation of 4 histamine receptorsand their distinct intracellular signals. In addition, differences in affinities of these receptorsare highly decisive...
Book Chapter
Series: Current Problems in Dermatology
Volume: 46
Published: 22 December 2014
10.1159/000366533
EISBN: 978-3-318-02763-1
... to be tightly regulated to avoid the development of immune responses that may potentially damage or destroy the integrity of the skin itself. Multiple immune cell populations, including the classical CD4 + Foxp3 + regulatory T cells [ 5 ](T-regs), invariant natural killer T cells [ 6 , 7 ,] mast cells [see 49...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 107
Published: 29 April 2013
10.1159/000345733
EISBN: 978-3-318-02325-1
... colonization and restriction of antigen uptake [ 1 ]. SIgA also maintains host mutualism with the indigenous microbiota [ 2 ]. Components of the gut microbiota activate not only the secretory antibody system, but also suppressive mechanisms, mainly depending on regulatory T (T Reg ) cells [ 3...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 29
Published: 09 September 2015
EISBN: 978-3-318-02809-6
...: Feasibility of ultrasound-guided percutaneous placement of peripheral nerve stimulation electrodes in a cadaver model: part one, lower extremity. Reg Anesth Pain Med 2008;33:551-557. 20. Huntoon MA, Hoelzer BC, Burgher AH, Hurdle MF, Huntoon EA: Feasibility of ultrasound-guided percutaneous placement...
Book Chapter
Series: Progress in Neurological Surgery
Volume: 33
Published: 22 January 2018
10.1159/000481084
EISBN: 978-3-318-06202-1
Book Chapter
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Book Chapter
Series: Progress in Neurological Surgery
Volume: 21
Published: 15 September 2008
10.1159/000155701
EISBN: 978-3-8055-8371-8