... Abstract Malignancies of the anterior skull base are rare and recur in 40–80% of treated cases, varying with substantial variance according to histology, stage at primary diagnosis, and other factors. Most recurrences manifest within 2–5 years after primary treatment, but some histologies can...

... Abstract Management options for residual or recurrent glioblastoma multiforme (GBM) are limited despite advances in surgical, chemotherapeutic, and radiotherapeutic techniques. Stereotactic radiosurgery (SRS) is often beneficial in such cases providing improved survival of patients, but still...

... Abstract In cases of recurrent gliomas, the treatment options are limited and not yet standardized. Choices usually include re-operation, systemic chemotherapy, salvage re-irradiation, and supportive care, which can be used either separately or in combination. From a surgical perspective...

... Abstract The most important causes of recurrence of benign pleomorphic adenoma are enucleation with intraoperative spillage and incomplete tumor excision in association with characteristic histologic findings for the lesion (incomplete pseudocapsule and the presence of pseudopodia). Most...

... Abstract The management of malignant salivary gland neoplasms is based on a surgical paradigm, with intraoperative findings and pathology guiding the role of local-regional adjuvant therapy. Despite high rates of local control, local relapse can be a dominant pattern of recurrence, presenting...

.... This chapter outlines an approach to the evaluation and treatment of children with recurrent fractures and describes three common scenarios involving infants, children with chronic illness and children without chronic illness. Introduction With growth, bone undergoes a process of modelling whereby...

... impairment but massive psychosocial impairment in specific communities such as vitiligo, are all suitable for further studies. Life course studies are particularly suitable for skin diseases due to their often chronic recurrent course, low mortality and their psychosocial aspects. The development...

... and insert into the belly of the various strap muscles. Anatomical variations of the ansa cervicalis are common; however, this generally does not preclude dissection of a branch of approximate size of and adequate length to the recurrent laryngeal nerve (RLN). Ansa cervicalis RLN anastomosis. The ansa...

... Abstract Juvenile-onset recurrent respiratory papillomatosis, caused by the human papilloma virus, is the most common benign neoplasm of the larynx in children. Recurrent respiratory papillomatosis is relatively rare, but it can have a significant impact on afflicted children and their family’s...

... Abstract FGFR-associated bone dysplasias and craniosynostosis can have an astonishingly high frequency of recurrent nucleotide substitutions, which are paternally derived and age-dependent. There is increased probability for these point mutations to occur in the paternal germline in an age...

... of Neurosurgery, St. John’s Hospital, Budapest, Hungary. Inall 43 cases, brachytherapy was used for surgically inoperable gliomas: in 32 cases for recurrentgliomas and in 11 cases as a primary treatment. Results of this study suggest that 125Ibrachytherapy for inoperable and recurrent gliomas is an effective...