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Book Chapter
Series: Contributions to Nephrology
Volume: 148
Published: 16 June 2005
10.1159/000086042
EISBN: 978-3-318-01170-8
... Abstract Renal cell carcinoma (RCC) represents one of the most common cancer types inthe Western World. One third of the RCC patients had metastasis at presentation with a poor5-year survival. Nephrectomy is the most important treatment modality of this disease, sincemost of the RCCs...
Book Chapter
Series: Contributions to Nephrology
Volume: 159
Published: 21 April 2008
10.1159/000125687
EISBN: 978-3-8055-8506-4
... Abstract Recent advances in understanding the molecular events associated with renal cell carcinoma(RCC) are revolutionizing the therapeutic options offered for patients with advancedstageRCC. These targeted approaches for RCC are based primarily on antiangiogenesisand/or specific kinase...
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445475
EISBN: 978-3-318-05884-0
... Abstract Acquired cystic kidney disease (ACKD) and renal cell carcinoma (RCC) are the most important manifestations of end-stage kidneys' structural changes. ACKD is caused by kidney damage or scarring and it is characterized by the presence of small, multiple cortical and medullary cysts...
Book Chapter
Series: Progress in Tumor Research
Volume: 41
Published: 19 February 2014
10.1159/000355906
EISBN: 978-3-318-02542-2
... Abstract Until recently, the standard treatment for metastatic renal cell carcinoma (RCC) was nonspecific immunotherapy based on interleukin-2 or interferon-α. This was associated with a modest survival benefit and with significant clinical toxicities. The understanding of numerous molecular...
Book Chapter
Series: Progress in Tumor Research
Volume: 42
Published: 09 September 2015
10.1159/000436988
EISBN: 978-3-318-05590-0
... Abstract The development of new immunomodulatory monoclonal antibodies targeting the CTLA-4 or PD-1 axis has led to a revival of research on immunotherapies in solid tumours including renal cell cancer (RCC). The initial results observed with these monoclonal antibodies in the treatment...
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 128
Published: 04 October 1999
10.1159/isbn.978-3-318-00465-6
EISBN: 978-3-318-00465-6
Book Chapter
Series: Karger eBooks Non-Series Collection
Published: 22 May 2014
10.1159/000358030
EISBN: 978-3-318-02397-8
... will show CK7 positivity and CK20 negativity, except for gastrointestinal adenocarcinomas which show the reverse immunophenotype (i.e. CK20-positive and CK7-negative) and renal cell carcinomas (RCCs) of a nonpapillary type which are CK7-negative. Thus, morphological features and site-specific immunomarkers...
Book Chapter
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/000125936
EISBN: 978-3-8055-8545-3
... Abstract Renal cell carcinoma (RCC) is associated with a poor prognosis and there is a need forbiomarkers to assist at all stages of disease management including diagnosis, prognosis,monitoring for relapse and predicting response to therapy. Additionally, identification of newtherapeutic...
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 159
Published: 21 April 2008
10.1159/isbn.978-3-8055-8506-4
EISBN: 978-3-8055-8506-4
Book Chapter
Series: Frontiers of Hormone Research
Volume: 45
Published: 21 March 2016
10.1159/000442327
EISBN: 978-3-318-02738-9
... or the ‘fossula hypophyseos' [ 2 ]; - variants from normal, such as unusual intrasellar arteries, an unusually well-developed inferior coronal sinus or a sellar spine [ 2 ]; - intrasellar cysts, such as Rathke's cleft cysts (RCC), that are encountered very frequently [ 2 ]; - a small sella turcica can...
Book
Book Cover Image
Published: 30 April 1996
10.1159/isbn.978-3-318-04356-3
EISBN: 978-3-318-04356-3
Book Chapter
Series: Endocrine Development
Volume: 17
Published: 24 November 2009
10.1159/000262537
EISBN: 978-3-8055-9303-8
... small quantities of other metabolites or absence of any detectable metabolite peak [ 27 , 28 ]. Rathke's Cleft Cysts Rathke's cleft cysts (RCC) are intrasellar and/or suprasellar benign cysts containing mucoid material, accounting for fewer than 1% of all intracranial masses [ 8...
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 148
Published: 16 June 2005
10.1159/isbn.978-3-318-01170-8
EISBN: 978-3-318-01170-8
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 17
Published: 29 November 2013
10.1159/000350348
EISBN: 978-3-318-02423-4
.... All refractory cytopenias without an excess of blasts are pooled into a single category of refractory cytopenia of childhood (RCC) (peripheral blood blast count <2% and bone marrow blasts <5%). In contrast to adult practice, the MDS subtypes 5q- syndrome and refractory anaemia with ring...
Book
Book Cover Image
Series: Progress in Tumor Research
Volume: 41
Published: 19 February 2014
10.1159/isbn.978-3-318-02542-2
EISBN: 978-3-318-02542-2
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/isbn.978-3-318-05884-0
EISBN: 978-3-318-05884-0
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/isbn.978-3-8055-8545-3
EISBN: 978-3-8055-8545-3
Book
Book Cover Image
Series: Frontiers of Hormone Research
Volume: 34
Published: 15 March 2006
10.1159/isbn.978-3-318-01300-9
EISBN: 978-3-318-01300-9
Book Chapter
Series: Contributions to Nephrology
Volume: 188
Published: 18 May 2016
10.1159/000445474
EISBN: 978-3-318-05884-0
... attenuated US beam and (2) the lateral acoustic cones resulting from the attenuation/refraction of incident US beam on the cyst convex edge. Cyst wall remodelling secondary to bleeding or infection requires careful differential diagnosis with cystic renal cell carcinoma (RCC), which accounts for 10...
Book
Book Cover Image
Series: Progress in Tumor Research
Volume: 42
Published: 09 September 2015
10.1159/isbn.978-3-318-05590-0
EISBN: 978-3-318-05590-0