... Abstract Long-term cancer survivors are at high risk of developing cardiac complications from the treatments, both systemic agents and thoracic irradiation, received to cure the primary tumor. Modern advances, particularly in the field of radiotherapy, aim to reduce the risk of cardiovascular...

... Abstract Ideally, each patient with a malignancy who is eligible for radiation therapy should receive the most tumoricidal form of this this treatment with the lowest possible risk of toxicity. To overcome radiotherapy resistance, some patients would benefit from a more aggressive approach...

... Abstract Treatment planning for radiotherapy has become unthinkable without computer algorithms for dose optimization. Although the need for optimization algorithms originated from the complexity of treatment delivery technology such as intensity-modulated radiotherapy, volumetric-modulated arc...

...Historical Overview and Definition of Stereotactic Body Radiotherapy In the mid-1990s, the principles and practice of stereotactic body radiotherapy (SBRT) were transferred from cranial stereotactic radiotherapy/radiosurgery by pioneering work at the Karolinska Hospital in Sweden [ 1...

... Abstract Fractionated radiotherapy (FRT) plays a critical role in the management of gliomas. For glioblastoma, the irradiation dose of 60 Gy in 30 fractions with concomitant and adjuvant temozolomide is currently considered as a standard of treatment, and further dose escalation has failed...

... Abstract There is an established role for post-operative radiotherapy in the treatment of benign and malignant salivary gland tumours. For benign disease, the addition of radiotherapy improves local tumour control in cases with incomplete excision, involved surgical margins or multi-focal...

... Abstract Radiotherapy is an important cornerstone in cancer treatment. Ionizing gamma-irradiation is capable of inducing DNA damage and consequential cell death in a precise and effective manner. In recent years it has become clear, however, that this is not the only relevant mechanism...

.... Technological advances in the last few decades in medical imaging and radiotherapy delivery have led to the development of highly complex radiation delivery systems such as intensity modulated radiotherapy, which can be utilized to conformally treat complex tumor shapes while minimizing radiation dose...

... Abstract Hyperfractionation and hypofractionation combined with acceleration have been investigated in stage I-III NSCLC patients. In stage I tumors, hypofractionated radiation schedules given with highly conformal stereotactic body radiotherapy (SBRT) techniques have been proven safe...

... Abstract The intrathoracic growth of the tumor causes several severe symptoms as cough, dyspnea, chest pain, hemoptysis, hoarseness, anorexia/nausea, and dysphagia. In patients with manifest or threatening symptoms radiotherapy (RT) as an effective measure should be implemented...

... irradiation should now routinely be used for all patients who have responded to chemotherapy. Thoracic radiotherapy is often reserved for palliation. However, the high incidence of residual disease after chemotherapy and the reported beneficial effect of radiotherapy in a single study has led to two clinical...

... Abstract Purpose: To assess the quality of life (QOL) of extremely long-time survivors with germinoma mainly treated with radiotherapy. Patients and Methods: We enrolled 52 of 68 patients who received radiotherapy between 1968 and 1995 at our hospital. They were 41 males and 11 females...