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pubertal

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Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438957
EISBN: 978-3-318-02789-1
... Abstract In humans, there is a considerable variation in age of onset of puberty. Twin studies have indicated that pubertal timing is a highly heritable trait. Recently, a few rare genetic causes of precocious puberty have been reported as well as genetic mutations associated with isolated...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438877
EISBN: 978-3-318-02789-1
... for a better understanding and eventually management of pubertal disorders of escalating prevalence worldwide. Maturation of the Hypothalamic-Pituitary-Gonadal Axis and Puberty: A Developmental Continuum Puberty is a fascinating developmental period when sexual and somatic maturation is achieved...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438883
EISBN: 978-3-318-02789-1
... Abstract Sexual maturation is closely tied to growth and body weight gain, suggesting that regulative metabolic pathways are shared between somatic and pubertal development. The pre- and postnatal environment affects both growth and pubertal development, indicating that common pathways...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438884
EISBN: 978-3-318-02789-1
... Abstract Caloric-protein malnutrition can slow growth and cause pubertal delay. This chapter focuses on endocrine abnormalities and pubertal alterations in patients with eating disorders, childhood obesity, the female athlete triad and children cancer survivors. Patients with anorexia nervosa...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438885
EISBN: 978-3-318-02789-1
... Abstract The aim of this chapter is to revise some common views on changes in pubertal timing. This revision is based on recent epidemiological findings on the clinical indicators of pubertal timing and data on environmental factor effects and underlying mechanisms. A current advancement...
Book
Book Cover Image
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/isbn.978-3-318-02789-1
EISBN: 978-3-318-02789-1
Book Chapter
Series: Pediatric and Adolescent Medicine
Volume: 19
Published: 27 January 2015
10.1159/000368112
EISBN: 978-3-318-02799-0
... Abstract The process of pubertal development is only partly understood but is thought to be influenced by many partially unknown factors. During the 20th century, there was a secular trend towards earlier pubertal development. Due to the rising epidemic of childhood obesity, the relationship...
Book Chapter
Series: Medicine and Sport Science
Volume: 55
Published: 29 September 2010
10.1159/000321969
EISBN: 978-3-8055-9559-9
... Abstract Historical data suggest that body composition is intricately involved in pubertal development. Progression through puberty is dependent on the interaction between the growth hormone-insulin-like growth factor-1 (GH-IGF-1) axis, reproductive and metabolic hormones as well as pro...
Book Chapter
Series: Medicine and Sport Science
Volume: 55
Published: 29 September 2010
10.1159/000321976
EISBN: 978-3-8055-9559-9
... markers are products of osteoblasts and osteoclasts which can be measured in urine or blood. The increase in different markers of bone turnover coincides with the pubertal growth spurt and thereafter markers decline until they converge into adult values. The initiation of puberty is accompanied...
Book Chapter
Series: Medicine and Sport Science
Volume: 55
Published: 29 September 2010
10.1159/000321979
EISBN: 978-3-8055-9559-9
... mentioned study [ 37 ] may be due to the lower exercise intensity used. Results of the study indicated that there are no changes in ghrelin and leptin in response to moderately intense aerobic exercise in young boys regardless of the pubertal stages of development. Souza et al. [ 39 ] examined the effect...
Book Chapter
Series: Endocrine Development
Volume: 17
Published: 24 November 2009
10.1159/000262530
EISBN: 978-3-8055-9303-8
... thyroid hormone and growth hormone (and its downstream product, IGF-1). At adolescence there is the reawakening of the hypothalamic-pituitary-gonadal axis and its interaction with the GH/IGF-1 axis to subserve the pubertal growth spurt. The fat tissue-derived hormone, leptin and its receptor are likely...
Book Chapter
Series: Endocrine Development
Volume: 15
Published: 26 February 2009
10.1159/000207616
EISBN: 978-3-8055-9038-9
... puberty. As a consequence of these alterations of pubertal timing, both male and female survivors of childhood cancer may be at risk of adult short-stature, decreased bone-mineral density, absent or incomplete sexual development, and ultimately, reduced rates of fertility. Appropriate and timely...
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Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 106
Published: 12 February 2013
10.1159/000342545
EISBN: 978-3-318-02266-7
.... Childhood obesity is a growing and alarming problem, associated with several short-term and long-term metabolic and cardiovascular complications. In addition, there is evidence suggesting that excess adiposity during childhood influences growth patterns and pubertal development. Several studies have shown...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
10.1159/000438892
EISBN: 978-3-318-02789-1
... Abstract The overall goal of pubertal sex hormone replacement therapy (HRT) in girls is not only about development of secondary sexual characteristics, but also to establish an adult endocrine and metabolic milieu, as well as adult cognitive function. Estradiol (E 2 ) is the first choice...
Book Chapter
Series: World Review of Nutrition and Dietetics
Volume: 106
Published: 12 February 2013
EISBN: 978-3-318-02266-7
...-Yablonski G, Yackobovitch-Gavan M, Phillip M: Nutrition and bone growth in pediatrics. Pediatr Clin N Am 2011;58:1117-1140 4. Burt Solorzano CM, McCartney CR: Obesity and the pubertal transition in girls and boys. Reproduction 2010;140:399-410 5. Kaplowitz PB: Link between body fat and the timing...
Book Chapter
Series: Endocrine Development
Volume: 29
Published: 22 December 2015
EISBN: 978-3-318-02789-1
... of the world's adolescents: a synthesis of internationally comparable data. Lancet 2012;379:1665-1675. 3. Patton GC, Viner R: Pubertal transitions in health. Lancet 2007;369:1130-1139. 4. Tylee A, Haller DM, Graham T, Churchill R, Sanci LA: Youth-friendly primary-care services: how are we doing and what...
Book Chapter
Series: Endocrine Development
Volume: 22
Published: 30 July 2012
10.1159/000326624
EISBN: 978-3-8055-9337-3
... determinants are suggested by the still evolving pattern of the pubertal process both clinically and mechanistically. For instance, secular trends towards earlier breast development have been observed during the two past decades in some countries, resulting in possible skewing of the age distribution...