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proteomic

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Book Chapter
Series: Frontiers of Hormone Research
Volume: 53
Published: 16 October 2019
10.1159/000494910
EISBN: 978-3-318-06471-1
... “omics” approaches have been applied to create a holistic picture complementing the information generated by genetic studies. Proteomics and metabolomics have the potential advantage over genomics of integrating genetic and epigenetic influences, thereby facilitating interpretation of the molecular...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358021
EISBN: 978-3-318-02600-9
... be tackled by proteomics, which has been used increasingly along with genetics and other ‘-omics' approaches. In the present chapter, we explore some advances in proteomic studies involving brain tissue and cerebrospinal fluid collected from schizophrenic patients. We demonstrate that proteomic findings have...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358027
EISBN: 978-3-318-02600-9
... elucidated by quantification of proteins expressed by these cell populations. Furthermore, non-hypothesis-driven approaches may identify novel glial anomalies and point to new avenues for research. In this review we will discuss proteomic and metabolomic evidence for glial alterations in schizophrenia. While...
Book Chapter
Series: Advances in Biological Psychiatry
Volume: 29
Published: 23 May 2014
10.1159/000358028
EISBN: 978-3-318-02600-9
... Abstract Proteomics offers the ability to monitor and identify changes in protein expression and/or signalling pathways with high precision, accuracy and reproducibility. Proteomic techniques, including bioinformatics software, are steadily advancing, and technical improvements to the methods...
Book Chapter
Series: Contributions to Nephrology
Volume: 170
Published: 08 June 2011
10.1159/000325657
EISBN: 978-3-8055-9743-2
... marker for early detection of DN and a better biomarker is urgently needed. Recently, particularly after the completion of the Human Genome Project, proteomics (systematic analysis of proteins for their identity, quantity and function) has been recognized as anemerging subdiscipline of modern sciences...
Book Chapter
Series: Developments in Biologicals
Volume: 132
Published: 08 August 2008
10.1159/000317143
EISBN: 978-3-8055-9596-4
... Abstract Many factors play into the complexity of viral pathogenesis. Understanding viral pathogenesis is key to developing vaccines and treatments for viral diseases. One emerging area of research is proteomics, which is the study of the protein complement and functions of the genome. Many...
Book Chapter
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/000125936
EISBN: 978-3-8055-8545-3
... targets is a priority. Increased understanding of disease pathogenesis and the molecularchanges underlying tumour formation is essential to assist in the rational design ofsuch molecules. As the technologies underlying proteomics-based research have developed,they have been applied extensively...
Book Chapter
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/000125973
EISBN: 978-3-8055-8545-3
... has been characterized. Polypeptides constitute a heterogeneous group ofuremic molecules. Therefore, proteome analysis represents a new and promising analyticalapproach to identify new uremic toxins. Proteomic technologies cover applicability to abroad molecular mass range. For polypeptides >10 kDa...
Book Chapter
Series: Contributions to Nephrology
Volume: 160
Published: 19 May 2008
10.1159/000125981
EISBN: 978-3-8055-8545-3
... Abstract In the current era of large-scale biology, proteomics has evolved as a powerful, newtechnique that aims to identify, quantify, and analyze a large number of proteins in a functionalcontext. Therefore, proteomics can be used to study cellular pathways and identify diseasebiomarkers...
Book Chapter
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/000074603
EISBN: 978-3-318-01014-5
Book Chapter
Book Chapter
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/000074587
EISBN: 978-3-318-01014-5
Book Chapter
Book Chapter
Book Chapter
Series: Forum of Nutrition
Volume: 60
Published: 17 August 2007
10.1159/000107076
EISBN: 978-3-318-01499-0
... Abstract Proteomics has been widely applied to several biomedical fields in recent years. Thehigh-throughput capability of proteomics allows simultaneous examination of numerous proteinsand offers the possibility of a global analysis of proteins in cells, tissues or biofluids.The rapid progress...
Book Chapter
Series: Progress in Respiratory Research
Volume: 34
Published: 07 October 2005
10.1159/000088488
EISBN: 978-3-318-01240-8
... Abstract Microarrays (or arrays) and proteomics are powerful newtechnologies that have emerged in the post-genomic era andtheir applications in biomedical research fields are rapidlyexpanding.We aim in this chapter to encapsulate advancesmade in cystic fibrosis (CF) research through use...
Book Chapter
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/000074602
EISBN: 978-3-318-01014-5
Book
Book Cover Image
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/isbn.978-3-318-01014-5
EISBN: 978-3-318-01014-5
Book Chapter
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/000074585
EISBN: 978-3-318-01014-5
Book Chapter
Series: Contributions to Nephrology
Volume: 141
Published: 28 October 2003
10.1159/000074593
EISBN: 978-3-318-01014-5