Search Results for primary

... Abstract Primary fusion of the first metatarsophalangeal joint is a commonly performed procedure with good outcomes and high patient satisfaction rate. A variety of fixation techniques and implants have been described over the past decades. Of the different fixation methods, the use of a dorsal...

... avoiding the need for an interposition arthrodesis with a cortical graft, which is known for a higher nonunion rate than primary fusion. Postoperatively the patient was weightbearing as tolerated in a cast boot for 4 weeks followed by a shoe with stiff sole for 2 weeks. Radiographs at 6 weeks...

... Abstract Molar incisor hypomineralisation (MIH) and hypomineralised second primary molars (HSPMs) are commonly seen dental developmental problems with a mean prevalence of around 14% and 9%, respectively, but with a large variability in the reported prevalences. From the dental development, we...

... cancers (e.g., adenoid cystic carcinoma), sinonasal undifferentiated carcinoma (SNUC), and sinonasal neuroendocrine carcinoma (SNEC) are also reported [ 1 , 2 ]. Sinonasal primary mucosal melanoma, olfactory neuroblastoma (ONB), different types of sarcoma, hematolymphoid tumors, germ cell tumors...

... microsurgery (TLM) or transoral robotic surgery (TORS). Oncologic outcomes reported are comparable whatever modality is chosen, but better functional outcomes are observed in the RT/CRT and TLM/TORS-treated patients. Because of the high rate of second primary malignancies, which influences overall survival...

... analysis of multi-site head and neck trials and retrospective reviews [ 4 ]. Direct comparison between different treatment options is difficult due to the variable inclusion criteria, stages of disease, follow-up periods, primary and secondary end points, statistical analyses and confounded further...

...” designed for recurrent disease after an interval free of disease, TNM does not include patients with persistent disease. This is especially important in HPC, where local recurrence after CRT and primary surgery, has been reported to be around 40 and 15% respectively [ 39 ]. Evaluation of Recurrent...

... concentrations. Hypercalcemia may be distinguished in parathyroid-hypercalcemia and nonparathyroid hypercalcemia. The most common disorders include primary hyperparathyroidism (PHPT), malignancy, granulomatous diseases, and medications. PHPT is a disease characterized by excessive secretion of PTH. PHPT is most...

... Abstract Asymptomatic primary hyperparathyroidism has become the most common presentation of primary hyperparathyroidism in Europe and North America, and an increasingly common presentation in other parts of the world. As many as 25% of asymptomatic patients may develop indications...

... Abstract Individuals with a familial predisposition to the development of parathyroid tumors constitute a small minority of all patients with primary hyperparathyroidism (PHPT). These familial syndromes exhibit Mendelian inheritance patterns and the main causative genes in most families have...

... Abstract In line with reducing the invasiveness of interventions in permanent teeth and changes towards more biological approaches, there have also been moves away from traditional restorative approaches to managing primary teeth where carious dentine/lesions were completely excised...

... Abstract Primary hyperparathyroidism (PHPT) is a common disorder of mineral metabolism characterized by hypercalcemia and incompletely regulated, excessive secretion of parathyroid hormone from one or more of the parathyroid glands. PHPT is most often asymptomatic, but it does increase the risk...

... Abstract Treatment of advanced PCLs is limited and rarely reaches complete remission despite aggressive treatment modalities, such as polychemotherapy with various adverse effects. However, several monoclonal antibodies drug agents in patients with advanced primary cutaneous lymphomas...

... Abstract Primary adrenal hypercortisolism is mainly due to cortisol-producing adrenocortical adenomas, bilateral micronodular or macronodular disease, and adrenal carcinomas. Important advances in the pathophysiology of primary adrenal hypercortisolism have been made in the last few years...

... of primary adrenocortical insufficiency (PAI) in around 80-90% of cases [ 1 ]. Autoimmune PAI is also known as autoimmune Addison's disease (AAD), after the name of the physician who in 1855 described the disease and attributed it to a pathology of the adrenal glands. In AAD, autoimmune adrenalitis...

... Abstract In the sensory hair cells of the mammalian cochlea, the primary cilia in the planar cell polarity as well as the tight junctions in the epithelial cell polarity and the barrier are important to maintain normal hearing. Temperature-sensitive mouse cochlear precursor hair cells were used...

... that are performed, including imaging and tissue biopsy. A systematic approach to ensure resection with clear margins, management of the facial nerve, applicable extensions of the primary resection and management of the neck are presented. The key determinants of disease control, including the stage (early...