... Academy of Medicine) is customized to the woman’s pregravid BMI. As noted in the report, the amount and rate of weight gain for obese women was primarily based on data from women in the BMI range of 30–35 kg/m 2 , Obesity Grade I [ 43 ]. Thus, women with a BMI >35 kg/m 2 , receiving good prenatal care...

... successful. Fetal hyperandrogenemia and genital ambiguity have been shown to be preventable by prenatal administration of low‐dose dexamethasone initiated before the 9th week of gestation. In 7 of 8 at-risk pregnancies, the unaffected fetus is unnecessarily exposed to dexamethasone for weeks until...

... Abstract The majority of congenital heart defects (CHD) can be detected prenatally, although many patients still go undetected until after birth. The main goal of prenatal diagnosis is to improve the physical condition of the fetus and the outcome for the neonate. The ability to identify...

... and stress biology on fetal programming of body composition, obesity and metabolic function. We review empirical evidence for interactive effects between stress and nutrition, describe findings from some of our own recent studies on prenatal stress and stress biology, and discuss putative maternal-placental...

... (negative life events during pregnancy), fasting glucose levels were similar as in controls, while they showed significantly higher glucose and c-peptide response after an oral glucose load [ 4 ]. Entringer and coworkers also found prenatal stress to be associated with shorter leukocyte telomere length [ 5...

... Abstract There is increasing evidence to suggest that prenatal nutritional factors may have long-term effects on the offspring. Osteoporosis is a worldwide public health problem leading to both morbidity and mortality, through associated bone fractures. Although in clinical practice most effort...

... Abstract High-resolution and 3-dimensional ultrasound opens new possibilities for the examination of fetal bony structures. Prenatal ultrasound screening could potentially reveal most of the cases of craniosynostosis. Detailed expert examination allows for diagnosing most of syndromic...

... Abstract Prenatal treatment of congenital adrenal hyperplasia (CAH) with dexamethasone (DEX) has been in use since the mid- 1980s. Its effectiveness for reducing virilization of external genitalia is well established. DEX treatment has to be started in the 6th–7th postmenstrual week...

..., and is a determinant of later life risk of chronic diseases. Maternal pre-pregnancy weight and height are independently associated with birthweight and also modify the effects of pregnancy weight gain and interventions during pregnancy on birthweight and perinatal mortality. Other prenatal factors commonly known...

... Abstract Prenatal treatment of congenital adrenal hyperplasia (CAH) with dexamethasone to minimize the genital virilizationof external genitalia of affected girls has been in use since the mid-1980s. The positive effect of reducingvirilization is now established. However, experimental data from...

... in the female patient. Recent advances in molecular genetic analysisallow for prenatal diagnosis and treatment of at-risk fetuses. The objective of prenataldiagnosis and treatment of 21-OH deficiency is the prevention of prenatal virilization inaffected female infants, reducing the risks of sex misassignment...

... Abstract There are two main approaches to the prenatal confirmation or exclusion of Fanconianemia: functional testing and molecular testing. Functional testing involves the determinationof crosslink sensitivity either by chromosome breakage analysis or cell cycle testing.Indications...