... not confirm this data [ 6 , 7 ]. In our Institute for Pigmentary Disorders, the majority of patients with vitiligo (n = 2,648) are otherwise healthy. The disease often targets the young, starting in 50% of patients before the age of 20 years [ 2 ]. The cause of vitiligo remains, to date, unknown, although...

... youth. The hair follicle (HF) pigmentary unit is a wonderful tissue for studying mechanisms generally regulating aging, often before this becomes evident elsewhere in the body. Given that follicular melanocytes (unlike those in the epidermis) are regulated by the hair growth cycle, this cycle is likely...

.... There are a number of nonprescription but scientifically studied agents that focus specifically on skin texture, pigmentary changes, and elasticity, which will be reviewed here. There has long been a societal interest in products that can reverse the aging process as well as improve skin tone, texture...

... Abstract Age-related macular degeneration (AMD) is the leading cause of visual impairment in adults over the age of 55 years in industrialized countries. The intermediate stage of AMD is defined by the presence of large drusen and/or AMD pigmentary abnormalities on funduscopic examination...

... system. Early AMD is characterized by the presence of drusen and pigmentary abnormalities. Late AMD is associated with central visual loss and is characterized by the presence of choroidal neovascularization and/or geographic atrophy. Early AMD is associated with a number of biochemical abnormalities...

... Abstract Although in knowledgeable hands treatment of vascular lesions is unlikely to result in permanent unwanted sequelae, complications do occur. Erythema and edema are common side effects and can be treated with supportive care. Pigmentary abnormalities and scarring are among the most...

... Abstract Generalized vitiligo is an acquired disorder in which patches of depigmented skin, overlyinghair and oral mucosa result from progressive autoimmune loss of melanocytes from theinvolved areas. Perhaps the most common pigmentary disorder, vitiligo results from a complexinteraction...

... devices was being modified for a new use: fractional delivery of laser light [ 1 ]. Fractional lasers were developed to address the drawbacks of ‘confluent' resurfacing, which was limited by significant downtime and high risks of infection, pigmentary change, and scarring. While full-face resurfacing...

.... Futcher lines: a case report in pregnancy and literature review. Cutis. 2013;92(2):100–1. 25. Nakama T, Hashikawa K, Higuchi M, Ishii N, Miyasato M, Hamada T, et al. Pigmentary demarcation lines associated with pregnancy. Clin Exp Dermatol. 2009;34(8):e573–6. 26. Purnak S, Özcan D, Seçkin D...

..., Metwalli M: Topical liquiritin improves melasma. Int J Dermatol 2000;39:299–301. 18. Halder R, Nordlund J: Topical treatment of pigmentary disorders; in Nordlund J, et al (eds): The Pigmentary System: Physiology and Pathophysiology. Oxford, Blackwell, 2006, pp 1165–1174. 19. Lim JT: Treatment...

... patients. Clin Ophthalmol 2012;6:1935-1940. 44. Seymenoglu G, Baser EF: Efficacy of selective laser trabeculoplasty in phakic and pseudophakic eyes. J Glaucoma 2015;24:105-110. 45. Ritch R, Liebmann J, Robin A, Pollack IP, Harrison R, Levene RZ, Hagadus J: Argon laser trabeculoplasty in pigmentary...

.... Test spots should be made before treating the entire lesion. All of these measures can further enhance clinical outcomes as well as reduce the adverse events. Pigmented Lesions There are several acquired pigmentary conditions that are particularly common in darker-skinned patients...

... common topical skin-lightening agents and their mechanism of actions regarding where they interrupt the process of melanogenesis. Melanin Synthesis Melanin is the pigmentary component of the skin used to protect the DNA of keratinocytes from mutations secondary to ultraviolet (UV) radiation...

..., and treatment options in skin of color.J Clin Aesthet Dermatol. 2010;3(7):20–31. doi: PMC2921758 18. Dlova NC, Akintilo LO, Taylor SC. Prevalence of pigmentary disorders: a cross-sectional study in public hospitals in Durban, South Africa.Int J Womens Dermatol. 2019;5(5):345–8. doi: 10.1016/j.ijwd...

... lesions such as venous lakes and spider angiomas [ 16 - 19 ]. The continuous mode of CW lasers (e.g. argon laser) exceeds the vascular thermal relaxation time and frequently results in nonspecific thermal damage and post-procedural pigmentary changes (i.e. hypopigmentation or hyperpigmentation), thereby...

..., exfoliative, and pigmentary glaucoma, as well as high-risk ocular hypertension when IOP is not satisfactorily controlled with medication or as initial treatment. Mechanism The mechanism of IOP lowering by LT is not completely understood. The mechanical theory suggests that coagulation necrosis...

... and the biggest aesthetic concern for which dermatologists’ care or aesthetic supports are sought. Solar-induced pigmentary disorders are the third most common dermatosis observed in the black skin population, a burden shared by the young and the elderly [ 16 - 19 ]. Reports have shown that the motivation...